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Sunday, October 11, 2009

IDiot Logic

 
I'll just post this without comment because I can't, for the life of me, figure out the logic [Denyse O'Leary on Uncommon Descent; Serving the Intelligent Design Community: Off topic: Single payer health care]
Here I was recently treated to an interesting display of Darwinist logic.

A commenter demanded that I provide proof that in a single-payer health system like Canada’s, older people are being abandoned to die. Another suggested I just shut up about it.

Sorry. Go here for how bad it can get.

It’s a matter of simple logic, really. Sarah Palin’s death panels are alive and well in Canada because we have a single government payer health system.


Censorship at McGill

 
I believe that universities are special places. The primary objective of the university community is to learn and investigate. That goal should not be restricted or impeded by outside concerns, especially if those "concerns" are ideologically or politically motivated. Society relies on universities to harbor unconventional and unusual opinions. It's where the minority viewpoint can be protected until it becomes the majority, as happens so often in a progressive society.

The other objective of a university is disseminating knowledge. That's why students come to a university to learn and it's why universities offer public lectures. It's why students and faculty members are encouraged to speak out on controversial topics. Universities thrive on diversity and that's why the most extreme opinions can be heard on campuses. It's part of the deal.

We're all familiar with the attempts to censor unpopular opinions. Mostly we get upset when left-wing protests are suppressed as happened during the 60s when the anti-war demonstrations were opposed [see Kent State Shootings]. We know about attempts to fire communist and gay professors and we are outraged to learn that women are being discriminated against in the universities.

What about opinions that don't fall into the liberal camp? Are we upset when those opinions are suppressed in the universities? No, not so much. I'm constantly surprised and disappointed when I hear some of my colleagues urging the dismissal of creationist professors or trying to block IDiots from lecturing on campus.

That's stupid and hypocritical. The value of a university is only protected when all opinions are respected.1 You can't pick and choose which ones deserve protection and which ones should be censored. Universities don't function once you start down that path.

The McGill student newspaper has started down that path with an article about a student pro-life club: EDITORIAL: Choose Life crossed the line with Ruba event. The editors seem to have set themselves up as sole arbitrators of some kind of imaginary "line" that can't be crossed.
At 6 p.m. tonight, Choose Life, the Students' Society's pro-life club, will host a presentation by Jose Ruba, a co-founder of the Canadian Centre for Bio-Ethical Reform, titled "Echoes of the Holocaust." Ruba's speech will attempt to draw parallels between abortion and the Holocaust, by arguing that "dehumanization and denial of personhood has justified some of the greatest affronts to human dignity that the world has seen." The presentation refers to abortion as a "mass human rights violation" and includes graphic imagery such as photos of dead bodies at concentration camps followed by photos of supposedly aborted foetuses.

On Thursday night, SSMU Council voted to censure the event and to make Choose Life ineligible to receive funding if they go through with tonight's presentation. We commend them for that decision. The comparison of abortion to the Holocaust is not only horribly offensive and inaccurate, it is deliberately designed to be inflammatory. This event is not intended to foster debate - it is designed to be provocative and to distract from meaningful discussion of abortive rights.
These are the sorts of issues that test our mettle. Either you support freedom of expression on the campus or you don't. There's no middle ground where you support some expression but not others.2

The editors of The McGill Tribune have just failed the test.

Let's see how the Student Society of McGill University (SMU) does when they're put to the test. This is part of an An open letter from the SSMU Executive to McGill University regarding Choose Life.
An open letter from the SSMU Executive:

The SSMU Executive is incredibly concerned and upset about the response of McGill University to the recent "Echoes of the Holocaust" event, hosted by the SSMU club Choose Life. We feel that McGill University has not only disrespected the rights of the SSMU as the accredited representative body of all McGill undergraduate students, but also failed to protect students' rights.

McGill University has not respected SSMU Council and the SSMU Executives as representatives of the McGill undergraduate student population. When the SSMU Council passed a resolution officially and publically censuring the event "Echoes of the Holocaust", the SSMU Council clearly stated that for Deputy Provost (Student Life and Learning) Morton Mendelson to permit it to go forward would disregard the desire of the Council. In response Professor Mendelson argued that this resolution is a tyranny of the majority. Firstly, this is an offensive misrepresentation of the purpose of SSMU Council. The SSMU Council was acting on behalf of all undergraduate students, both in its representative capacity and in reaction to many conversations with students. Secondly, it is worrisome that the Deputy Provost interprets a large percentage of students being outraged and appalled at an event to be a tyranny of the majority. The SSMU had hoped that he would consider the impact as well as content of the presentation instead of ignoring the formal intervention of students' representative body by using the rhetoric of academic freedom.
So we're reduced to the point where academic freedom is just "rhetoric"?3

I remember the days when it was students who were advocating freedom of expression and administrators who were trying to suppress it. Now those students are administrators and we have a whole new generation of students who don't understand the meaning of freedom on a university campus. How times change.

Incidentally, a large group of students succeeded in preventing Jose Ruba from speaking at the event according to a report in The National Post: Tim Mak: McGill abortion advocates block opposing opinions. They sang songs for three hours until the organizers gave up and went home.

Here's a video of the first part of the event so you can see for yourselves what transpired. The students do not earn my respect for their behavior. They have the right of freedom of expression and they have the right to express their disagreement but they do not have the right to prevent contrary opinions from being expressed on a university campus.


The event prompts Tim Mak, a former employee of the Fraser Institute, to write ...
But these are university campuses nowadays, ruled by an arrogant minority on the left, who despite their paucity, believe they speak for everyone. "I don't think that this type of talk should be allowed to happen at McGill," said Eisenkraft Klein, one of the protestors arrested, in the McGill Tribune. "This is student space. This is not public property."

What conceit. Klein’s implication was that her opinions represented those of all McGill students, that student space was only for activities that conformed to her parochial political views. I’m by no means a supporter of the pro-life movement. But I am a supporter of the modern conservative movement – a movement that believes that freedom of speech means free speech for all. On the other hand, the left has found it convenient to hide behind the tenets of free speech when they want to, say, condemn Israel, but have found it much harder to extend the protections of free speech to positions they disagree with.

I’ve always found that the most interesting lecturers are those with whom I have the least in common. Who wants to spend a couple hours nodding affirmatively at PowerPoint slides? But we’ll never know what Ruba might have said, and all reasonable students have left to do is sing the free speech blues.
Some of you might be afraid that the world is coming to an end when I agree with someone like Tim Mak. Not so, there really are open-minded conservatives who defend freedom of expression. I'm proud to ally with them on this issue.

Call me an accommodationist ...

A good case can be made that exposing stupid ideas to the light of day—and to serious debate in the university community—is the best way to discredit them. (Ignoring them works, too.) Trying to suppress them is the best way to give them the publicity they thrive on and it has the exact opposite effect to what the protesters desire. So, in addition to objecting to the student's behavior on the grounds of protecting freedom of expression, I object on the grounds that it's a tactically stupid way to oppose kooks.


1. "Respected" doesn't mean you have to agree. You can vigorously oppose any idea that's expressed on a campus but you can't muzzle it on the grounds that you disagree.

2. Don't quibble about this. Yes, we can all think of some examples of expression that must be excluded—yelling "fire" in a crowded classroom—for example.

3. I'm aware of the fact that the term "academic freedom" can be misused. If Morton Mendelson used "academic freedom" to permit the event to go forward then that's unfortunate. There are better ways to describe the principle I defend—it's "freedom of expression on university campuses."

[Hat Tip: Canadian Cynic. I strongly disagree with him on this one.]

Saturday, October 10, 2009

Average Annual Global Temperatures and IDiots

 
Here's a chart of the average annual global temperature change over the past 150 years. I don't know about you, but to me there seems to be a bit of a trend.

The highest recorded temperature was in 1998 and last year the temperature was 0.08° lower than the year before. Nobody with an IQ over 50 thinks that the temperature has to increase every single year in order to demonstrate global warming.



Speaking of IQ, the BBC "climate correspondent" just wrote an article for BBC News: What happened to global warming?.
This headline may come as a bit of a surprise, so too might that fact that the warmest year recorded globally was not in 2008 or 2007, but in 1998.

But it is true. For the last 11 years we have not observed any increase in global temperatures.

And our climate models did not forecast it, even though man-made carbon dioxide, the gas thought to be responsible for warming our planet, has continued to rise.

So what on Earth is going on?
It's actually not quite as bad an article as it sounds. There's some interesting discussion about short-term trends and how to predict them. Unfortunately the author leaves the impression that global warming may not be caused by humans. In seven of the past eight years the global temperature has been higher than it has ever been except for 1998. Isn't that worth mentioning?

The interesting thing about this is that the exact quotation above is presented on Uncommon Descent under the same scary title: What happened to global warming?. There's no additional information to put the headline into context.

Why is there a correlation between the rejection of evolution and the rejection of other scientific discoveries? Isn't it obvious? The IDiots are not in the business of promoting the scientific theory of Intelligent Design Creationism. Their goal is to discredit science and they'll try anything at all to advance that goal.


Human Races

 
A discussion about human races has broken out in the comments to The Problem of Race .... Again. One of quesitions on that thread has come up many times in the past so I'm devoting a separate posting to the answer.

Hopefully, this will stimulate discussion and debate about the scientific data and evidence for genetically distinct humans populations. I want to get away from the other aspects of the debate about races since they always seem to devolve into accusations of racism and/or political correctness. (mea culpa)

anonymous asks,
i always feel in these discussions people are talking past each other, especially when they have differing definitions of words like 'race'. so to clarify matters for me, i would like Dr. Moran to give the likely number of races that currently exist, say something on the stability of such groupings,give examples (if possible) of these racial groupings along with their differing genetic markers e.g. race 1 - geographically located in region A & B, with unique (almost Unique) gene combination 1,3,4,5 occuring at frequencies A,B,C,E.
Are you serious? Please tell me this is a joke.

Are you one of those people who want to deny the existence of races just because your question can't be answered precisely in the manner you phrase it? That sounds very much like the kind of thinking I encounter when dealing with creationists.

Biology is messy. There are no nice and tidy boundaries around terms like race, species, or even higher taxonomic levels. You may not like it but you have to deal with it. If you understand evolution then it all makes sense and you know why things are so messy.

Our species is subdivided into many different genetically isolated(1) populations ranging from very small ones, such as the residents of Tristan da Cunha, to very large ones, such as Africans and Asians.

The term "race" usually refers to the largest populations within a species. In the case of humans, the group who migrated out of Africa founded a genetically isolated population that subsequently split into several different populations. The main ones are Asian, European, Australian, and American.

These are reasonable examples of races. Each of them can be subdivided into numerous examples of demes and populations. Their genetic distinctiveness is so obvious that most of us would have no difficulty identifying their members if we encounter them on the streets of a major cosmopolitan city.(2)

The African group from which the migrants split is "polyphyletic" and deciding how to divide it into races is problematic. However, it's clearly a group that's genetically distinct from the other races so it's not unreasonable to refer to the Africans as a race, as long as you keep in mind that there are subdivisions and that this group is much more genetically divers than the others.

The genetic distinctiveness of Africans is pretty obvious to me. I'm constantly surprised by those who pretend it doesn't exist. People of African ancestry certainly don't have any trouble recognizing that I'm Caucasian and that some of my other neighbors are Asian.

There are dozens of phylogenetic trees on the web showing these major splits and subdivisions. Probably the most famous is the mitochondrial tree but others show roughly the same tree. It would be hard to imagine anyone denying the existence of human races unless they completely reject that kind of analysis.

There are several commercial, for-profit, companies that are more than willing to take your money (and your DNA) and provide you with an analysis that identifies where your ancestors came from. They are able to do this because certain haplotypes evolved in certain parts of the world. The mitochondrial haplotypes are shown on the map above and the Y-chromosome haplotypes are shown on the map on the left.

Given all the publicity about tracing your genealogy by haplotyes and all the scientific papers on the genetic differences between races, it surprises me that in 2009 there are still people who question whether these genetic differences even exist.



1. "Genetically isolated" does not mean that there's no genes flow between populations. It means restricted gene flow. If gene flow was zero they the populations wouldn't be populations. They would be species.

2. This does not mean that there won't be examples where the identification is difficult and it doesn't deny the existence of interbreeding between races. If you're looking for that kind of example then you won't find it in humans or in any other species where the biological term race is commonly used.

[Photo Credit: Downtown Toronto]

Friday, October 09, 2009

Shame on Norway!

 
The 2009 Nobel Peace Prize was announced today by Thorbjørn Jagland, Chairman of the Norwegian Nobel Committee. It goes to President Barack Obama, a man who has been President of the United States for about nine months and is currently conducting two simultaneous invasions and occupations of foreign nations.

The United States "peaceably" threatens both Iran and North Korea with possible military strikes if they do not stop developing a nuclear weapons program. The United States deploys the largest, most deadly, military force the world has ever seen and is in no hurry to reduce its size.

I think Obama is a wonderful choice for President of the USA. He is far, far, better than many others who have sought that office. However, it does not follow from that that he merits the Nobel Peace prize. He doesn't. The Norwegian Nobel Committee should be ashamed of themselves.

Here's the press release. The committee is confusing hope and hype with actual results. Let's hope the promise of a better world works out over the course of the next few years or we might look back on this award with shock and awe. At the very least, we should expect a serious reduction in the American nuclear weapons stockpile, right? And we should expect UN Nuclear inspection teams to be visiting the USA, Russia, France, Great Britain, China, India, Pakistan, and Israel.

Who's holding their breath?
The Nobel Peace Prize for 2009

The Norwegian Nobel Committee has decided that the Nobel Peace Prize for 2009 is to be awarded to President Barack Obama for his extraordinary efforts to strengthen international diplomacy and cooperation between peoples. The Committee has attached special importance to Obama's vision of and work for a world without nuclear weapons.

Obama has as President created a new climate in international politics. Multilateral diplomacy has regained a central position, with emphasis on the role that the United Nations and other international institutions can play. Dialogue and negotiations are preferred as instruments for resolving even the most difficult international conflicts. The vision of a world free from nuclear arms has powerfully stimulated disarmament and arms control negotiations. Thanks to Obama's initiative, the USA is now playing a more constructive role in meeting the great climatic challenges the world is confronting. Democracy and human rights are to be strengthened.

Only very rarely has a person to the same extent as Obama captured the world's attention and given its people hope for a better future. His diplomacy is founded in the concept that those who are to lead the world must do so on the basis of values and attitudes that are shared by the majority of the world's population.

For 108 years, the Norwegian Nobel Committee has sought to stimulate precisely that international policy and those attitudes for which Obama is now the world's leading spokesman. The Committee endorses Obama's appeal that "Now is the time for all of us to take our share of responsibility for a global response to global challenges.
What does the White House have to say? Surprisingly, Obama is being very candid.
"I am both surprised and deeply humbled," Obama said at the White House.

"I do not view it as a recognition of my own accomplishments. But rather as an affirmation of American leadership. ... I will accept this award as a call to action."

Obama said he did not feel he deserves "to be in the company" of past winners, but would continue to push a broad range of international objectives, including nuclear non-proliferation, a reversal of the global economic downturn, and a resolution of the Arab-Israeli conflict.

He acknowledged the ongoing U.S. conflicts in Iraq and Afghanistan, noting that he is the "commander in chief of a country that is responsible for ending" one war and confronting a dangerous adversary in another.
The Associated Press story seems to be typical of the responses from around the world [President Barack Obama wins Nobel Peace Prize]. I think this is going to make Obama's life more difficult, not easier. It may have the exact opposite effect to what well-meaning members of the prize committee expected. This will go down as one of the most controversial awards in recent memory.
Many observers were shocked by the unexpected choice so early in the Obama presidency, which began less than two weeks before the Feb. 1 nomination deadline and has yet to yield concrete achievements in peacemaking.

Some around the world objected to the choice of Obama, who still oversees wars in Iraq and Afghanistan and has launched deadly counter-terror strikes in Pakistan and Somalia.

Members of the Norwegian Nobel Committee said their choice could be seen as an early vote of confidence in Obama intended to build global support for his policies. They lauded the change in global mood wrought by Obama's calls for peace and cooperation, and praised his pledges to reduce the world stock of nuclear arms, ease American conflicts with Muslim nations and strengthen the U.S. role in combating climate change.

Aagot Valle, a lawmaker for the Socialist Left party who joined the committee this year, said she hoped the selection would be viewed as "support and a commitment for Obama."

"And I hope it will be an inspiration for all those that work with nuclear disarmament and disarmament," she told The Associated Press in a rare interview. Members of the Nobel peace committee usually speak only through its chairman.

The peace prize was created partly to encourage ongoing peace efforts but Obama's efforts are at far earlier stages than past winners'. The Nobel committee acknowledged that they may not bear fruit at all.

"He got the prize because he has been able to change the international climate," Nobel Committee chairman Thorbjoern Jagland said. "Some people say, and I understand it, isn't it premature? Too early? Well, I'd say then that it could be too late to respond three years from now. It is now that we have the opportunity to respond — all of us."


The Food Industry Depends on the Fact that Evolution Doesn't Happen!

 
Nobody has ever seen life created in peanut butter.

This is one of those videos where you don't know whether to laugh, or cry.




[Hat Tip: John Pieret at Thoughts in a Haystack: Peanut Butter and Bananas ... Yum!]

I'm Starting an Evolution Revolution

 
The University of Toronto is in the process of reorganizing its introductory biology courses. The new proposal is to offer two half courses in first year and two in second year. The expectation is that all life science students will take all four courses.

To give you an idea of the numbers, the anticipated enrolment for the first year courses is 1920 students and for the second year courses about 1500 students. These are the courses that will make the biggest impact on our students when it comes to understanding basic biology.

Here they are ....

BIO120H: Adaptation and Biodiversity
BIO130H: Molecular and Cell Biology

BIO220H: From Genomes to Ecosystems in a Changing World
BIO230H: From Genes to Organisms

There's a lot that's wrong with this proposal but I'm focusing on the teaching of evolution. Everyone agrees that it's important to teach evolution and teach it correctly. I don't think a course entitled "Adaptation and Biodiversity" is going to do an adequate job, especially since the fossil record is completely ignored and there's no serious attempt to teach the history of life. Population genetics gets only a single lecture in the middle of the course.

I'm trying to start a revolution by convincing my colleagues to vote down these proposals on the grounds that we can do much better. At the very least, the decision should be postponed for a year so we can debate the issues. The proposals were first circulated last week and the recommendation of the Life Sciences Curriculum Committee is going to be decided today. If they recommend in favor of adopting the proposals, then it's highly unlikely that the recommendation will be overturned at the next level. That's no way to run a university.

Yesterday I bumped into my colleague, Paul Hamel, as I was on my way to Tim Hortons. He asked me what I was up to and I told him I was trying to start a revolution. His advice? "Don't quit your day job!"

(In order to appreciate this comment, you probably need to know that Paul is one of the most radical members of our faculty and he's been fighting to change the system, and our society, for several decades.)

I think most of you can see the problem with the BIO120H course title. The first sentence of the course description is, "Principles and concepts of evolution and ecology related to origins of adaptation and biodiversity." Since much of the biodiversity around us is not due to adaptation, it seems like a strange way to describe "principles and concepts."

That's not the only thing wrong with the courses but this isn't the place to go into more detail. The problem I face is that it is very difficult to convince my colleages that there's something wrong with the way we propose to teach evolution since very few of them understand evolution. In my case the problem is compounded by the fact that the course instructor, Spencer Barrett, is a highly respected evolutionary biologist with lots of publications in prestigious journals.

I'm not optimistic. Making changes at a big university is like trying to herd together a bunch of cats and get them to cooperate in turning a full loaded supertanker. It can be done but it's a lot of work.

Anyway, this is a long-winded introduction to the real reason for this posting. I want to highlight a posting by Ryan Gregory who explains why it's important to teach evolution and what level of detail is needed [How detailed an understanding of evolution do we need?]. Here's a teaser, get on over to Genomicron and read the whole thing.
If you mean “students enrolled in science programs,” either undergraduates or grad students (as in our study), then I would say that a good working knowledge of evolutionary theory, though not a full understanding of all its nuances, should be a major goal. Again, evolution is the unifying principle of biology, and without grasping how it works, one cannot make sense of the history and current diversity of life on this planet.

UPDATE: The committee met and the courses were approved without much debate.



Thursday, October 08, 2009

Columbine and Creationism: A Case Study

 
Here's an excellent example of the fallacious argument referred to as "guilt by association." The idea is that you develop an association between some evil person and the position you want to attack.

For example, suppose you wanted to show that fundamentalist Christianity was bad. What you do is find some fundamentalist Christian who behaved immorally—not hard to do—then allow readers to draw the "obvious" conclusion.

Or, you could do the same thing with those who accept evolution as Barry Arrington does on Uncommon Descent [Darwin at Columbine Redux].
As the attorney for the families of six of the students killed at Columbine, I read through every single page of Eric Harris’ jounals; I listened to all of the audio tapes and watched the videotapes, including the infamous “basement tapes.” There cannot be the slightest doubt that Harris was a worshiper of Darwin and saw himself as acting on Darwinian principles. For example, he wrote: “YOU KNOW WHAT I LOVE??? Natural SELECTION! It’s the best thing that ever happened to the Earth. Getting rid of all the stupid and weak organisms . . . but it’s all natural! YES!”

Elsewhere he wrote: “NATURAL SELECTION. Kill the retards.” I could multiply examples, but you get the picture.

It was no coincidence that on the day of the shootings Harris wore a shirt with two words written on it: “Natural Selection.”

I am not suggesting that Auvinen’s and Harris’ actions are the inevitable consequences of believing in Darwinism. It is, however, clear that at least some of Darwin’s followers understand “survival of the fittest” and the attendant amorality at the bottom of Darwinism as a license to kill those whom they consider “inferior.” Nothing could be more obvious.
For the record, I reject all attempts to discredit Christianity by pointing to priests who molest children; the fact the Kent Hovind is in prison; or the tribulations of Jimmy Swaggart. We can gloat about those incidents and revel in the hypocrisy but they say nothing at all about the truth of Christianity.

Similarly, I do not apologize for nor condone the behavior of stupid people who accept evolution. It's irrelevant to the debate over the facts of evolution.

Everyone should adopt this position. Unfortunately, there are quite a few people on the other side who get all uppity whenever a Christian is caught with his pants down but see nothing wrong with blogging about evil evolutionists.

The word you're looking for is "hypocrisy." It seems to be quite common on that side of the debate.



Junk DNA: A Case Study in Scientific Controversy

 
I strongly support the concept of junk DNA and I reject the idea that a significant percentage more than 10% of the DNA in our genome has a function. This is my informed opinion.

This is a genuine scientific controversy, one that I bring to the attention of my students. We are discussing controversies, misunderstandings, and frauds. This one counts as a scientific controversy.

Of course, it's also part of the rationalism vs superstition debate since creationists have a hard time explaining junk DNA. The Intelligent Design Creationists, in particular, are almost duty-bound to oppose the concept. For an excellent example of how the IDiots exploit a genuine scientific controversy see: How The Junk DNA Hypothesis Has Changed Since 1980 by Richard Sternberg .

THEME

Genomes & Junk DNA
It all sounds very much like science. The trick is to put as much science into the discussion as possible, while keeping the distortions and misrepresentations to a mimimum. It's best to omit all references to other points of view 'cause that gives the impression that the scientific community is opposed to junk DNA.


One Nation Under God

 

Here's a little quiz. What nation is being referred to here?

Right. Boy, you guys are clever.

This image is so disgusting on so many levels that one hardly knows where to begin. Fortunately, I suspect most of you have already seen the PZ Myers take-down of a few days ago [The goggles! They do nothing!].

I couldn't resist re-posting the image. If you visit the websit at McNaughton Fine Art you'll get an added bonus. You can mouse over any of the figures and get an explanation.

Look in the lower-right corner. Why is that Supreme Court Justice holding his head in his hands?

Who is that person with his arm partially raised at the bottom of the picture in the lower-left corner? Why that's an immigrant, don't you know?
Why does he have his hand up like that? There are many good people in America, they are not all Christian. I wanted him to have a look of shock when he realizes where the source of America's greatness comes from as he sees Christ holding the Constitution. We live in a country where we are free to worship as we please.
My favorite is the Professor, sitting on the top step in the lower-right.
He tightly hold his "Origin of Speces" book by Charles Darwin. This represents the liberal lefts control of our educational system. His smug expression describes the attitude of many of the educational elite. There is no room for God in education. There is contempt for any other viewpoints. Humanism dominates the educational system of America and I believe that is wrong. Notice that he is the only one sitting on the top step. He tries to place himself on an equal footing with God, but he is still nothing next to the intelligence of the Creator.
For even more fun and games, try and guess which Presidents get to walk with Jesus and which ones are left out?

Who is your favorite person? Can you find Satan? How about Waldo? (Wally?)



Boring ....

 
Chris Mooney, Matt Nisbet, and Josh Rosenau got their knickers in a knot last week for thinking the Richard Dawkins had become an accommodationist [see Is Richard Dawkins an Accomodationist?].

Dawkins promptly denied it. That leaves these three accommodationists will little choice but to apologize for being so stupid. For an example of how Chris Mooney admits he was wrong (not) see his latest posting: How Richard Dawkins Communicates Evolution (Surprise, It's Not the Same Thing as Atheism).

PZ Myers takes the time to demolish the Mooney posting using images of sad puppies [My regrets on your traumatic brain damage!]. It ain't pretty.

My concern is that Chris Mooney isn't holding up his end of the fight. His postings are becoming quite boring.


The Problem of Race .... Again

 
The current politically correct view of human races is that they don't exist. Surprisingly, this view has been adopted by many scientists, including biologists, who should know better.

Bruce T. Lahn and Lanny Ebenstein have published an opinion piece in this week's issue of Nature. Everyone should read it [Let's celebrate human genetic diversity].

They begin by pointing out the problem and then they state their position.
The current moral position is a sort of 'biological egalitarianism'. This dominant position emerged in recent decades largely to correct grave historical injustices, including genocide, that were committed with the support of pseudoscientific understandings of group diversity. The racial-hygiene theory promoted by German geneticists Fritz Lenz, Eugene Fischer and others during the Nazi era is one notorious example of such pseudoscience. Biological egalitarianism is the view that no or almost no meaningful genetically based biological differences exist among human groups, with the exception of a few superficial traits such as skin colour3. Proponents of this view seem to hope that, by promoting biological sameness, discrimination against groups or individuals will become groundless.

We believe that this position, although well-intentioned, is illogical and even dangerous, as it implies that if significant group diversity were established, discrimination might thereby be justified. We reject this position. Equality of opportunity and respect for human dignity should be humankind's common aspirations, notwithstanding human differences no matter how big or small. We also think that biological egalitarianism may not remain viable in light of the growing body of empirical data (see box).
These guys seem to be a bit late in realizing that the scientific data doesn't support the politically correct "biological egalitarianism" viewpoint but, as they say, better late than never.

Here's their bottom line.
  • Promoting biological sameness in humans is illogical, even dangerous
  • To ignore the possibility of group diversity is to do poor science and poor medicine
  • A robust moral position is one that embraces this diversity as among humanity's great assets
Bravo! I'm glad that more and more scientists are speaking out on this issue.


Lahn, B.T. and Ebenstein, L. (2009) Let's celebrate human genetic diversity. Nature 461:726-728 [Nature]

[Hat Tip: Nils Reinton at BIOpinionated: I Wish I Wrote This (me too! -LAM)]

Wednesday, October 07, 2009

Tomorrow's Weather: 40% Chance of Rain

 
When you are told that there's a 40% chance of rain tomorrow, what do you think? When you see the hourly forecasts and learn that for each hour in the morning there's a 40% chance of rain but in the afternoon there's only a 30% chance of rain in each hour, what do you think?

Find out how to interpret these numbers by reading Nick Anthis at The Scientific Activist: Bad Math at The Weather Channel.


[Photo Credit: South African National Parks]

The Ribosome and the Central Dogma of Molecular Biology

The Nobel Prize website usually does an excellent job of explaining the science behind the prizes. The STRUCTURE AND FUNCTION OF THE RIBOSOME is a good explanation of reasons why the 2009 Nobel Prize in Chemistry was awarded for work on the ribosome.

Unfortunately, the article begins by perpetuating a basic misunderstanding of the Central Dogma of Molecular Biology.
The ribosome and the central dogma. The genetic information in living systems is stored in the genome sequences of their DNA (deoxyribonucleic acid). A large part of these sequences encode proteins which carry out most of the functional tasks in all extant organisms. The DNA information is made available by transcription of the genes to mRNAs (messenger ribonucleic acids) that subsequently are translated into the various amino acid sequences of all the proteins of an organism. This is the central dogma (Crick, 1970) of molecular biology in its simplest form (Figure 1)

This is not the Central Dogma according to Crick (1970). I explain this in a posting from two years ago [Basic Concepts: The Central Dogma of Molecular Biology].

In both his original paper (Crick, 1958) and the 1970 update, Crick made it very clear that the Central Dogma of Molecular Biology is ....
The Central Dogma. This states that once “information” has passed into protein it cannot get out again. In more detail, the transfer of information from nucleic acid to nucleic acid, or from nucleic acid to protein may be possible, but transfer from protein to protein, or from protein to nucleic acid is impossible. Information means here the precise determination of sequence, either of bases in the nucleic acid or of amino acid residues in the protein.
The diagram that's usually attributed to the central dogma is actually the Sequence Hypothesis. Crick was well aware of the confusion and that's why he wrote the 1970 paper. It was at a time when the so-called "Central Dogma" had been "overthrown" byt the discovery of reverse transcriptase.

Since then the false version of the Central Dogma has been disproven dozens and dozens of times—it's a minor cottage industry.

Here's what Crick says about this false version of the Central Dogma in his 1970 paper—the one quoted at the top of this page.
It is not the same, as is commonly assumed, as the sequence hypothesis, which was clearly distinguished from it in the same article (Crick, 1958). In particular, the sequence hypothesis was a positive statement, saying that the (overall) transfer nucleic acid → protein did exist, whereas the central dogma was a negative statement saying that transfers from protein did not exist.
Let's try and get it right. It will have the great benefit of stopping us from putting up with any new papers that refute the Central Dogma of Molecular Biology!

It will also encourage critical thinking. Haven't you ever wondered why there is a Central Dogma when reverse transcriptase, splicing, epigenetics, post-translational modification, chromatin rearrangements, small regulatory RNAs, and just about everything else under the sun, supposedly refutes it?


Crick, F.H.C. (1958) On protein synthesis. Symp. Soc. Exp. Biol. XII:138-163,

Crick, F. (1970) Central Dogma of Molecular Biology. Nature 227, 561-563. [PDF file]

2009 Nobel Prize in Chemistry

 
"for studies of the structure and function of the ribosome"

This one's not unexpected. Almost everyone knows that there should be a Nobel Prize for the ribosome [see Nobel Prize Predictions]. Problem is, Harry Noller was on most people's short list. He's been working on the problem since 1968 and has published more than 200 papers on ribosome structure and function. This is going to be a controversial decision.

Here's the press release.
Press Release

7 October 2009

The Royal Swedish Academy of Sciences has decided to award the Nobel Prize in Chemistry for 2009 jointly to

Venkatraman Ramakrishnan, MRC Laboratory of Molecular Biology, Cambridge,
United Kingdom

Thomas A. Steitz, Yale University, New Haven, CT, USA

Ada E. Yonath, Weizmann Institute of Science, Rehovot, Israel


"for studies of the structure and function of the ribosome"


The ribosome translates the DNA code into life

The Nobel Prize in Chemistry for 2009 awards studies of one of life's core processes: the ribosome's translation of DNA information into life. Ribosomes produce proteins, which in turn control the chemistry in all living organisms. As ribosomes are crucial to life, they are also a major target for new antibiotics.

This year's Nobel Prize in Chemistry awards Venkatraman Ramakrishnan, Thomas A. Steitz and Ada E. Yonath for having showed what the ribosome looks like and how it functions at the atomic level. All three have used a method called X-ray crystallography to map the position for each and every one of the hundreds of thousands of atoms that make up the ribosome.

Inside every cell in all organisms, there are DNA molecules. They contain the blueprints for how a human being, a plant or a bacterium, looks and functions. But the DNA molecule is passive. If there was nothing else, there would be no life.

The blueprints become transformed into living matter through the work of ribosomes. Based upon the information in DNA, ribosomes make proteins: oxygen-transporting haemoglobin, antibodies of the immune system, hormones such as insulin, the collagen of the skin, or enzymes that break down sugar. There are tens of thousands of proteins in the body and they all have different forms and functions. They build and control life at the chemical level.

An understanding of the ribosome's innermost workings is important for a scientific understanding of life. This knowledge can be put to a practical and immediate use; many of today's antibiotics cure various diseases by blocking the function of bacterial ribosomes. Without functional ribosomes, bacteria cannot survive. This is why ribosomes are such an important target for new antibiotics.

This year's three Laureates have all generated 3D models that show how different antibiotics bind to the ribosome. These models are now used by scientists in order to develop new antibiotics, directly assisting the saving of lives and decreasing humanity's suffering.