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Friday, August 23, 2013

Some Questions for IDiots

Here's a short quiz for proponents of Intelligent Design Creationism. Let's see if you have been paying attention to real science. Please try to answer the questions below. Supporters of evolution should refrain from answering for a few days in order to give the creationists a chance to demonstrate their knowledge of biology and of evolution.

The bloggers at Evolution News & Views (sic) are promoting another creationist book [see Biological Information]. This time it's a collection of papers from a gathering of creationists held in 2011. The title of the book, Biological Information: New Perspectives suggests that these creationists have learned something new about biochemistry and molecular biology.

One of the papers is by Jonathan Wells: Not Junk After All: Non-Protein-Coding DNA Carries Extensive Biological Information. Here's part of the opening paragraphs.
James Watson and Francis Crick’s 1953 discovery that DNA consists of two complementary strands suggested a possible copying mechanism for Mendel’s genes [1,2]. In 1958, Crick argued that “the main function of the genetic material” is to control the synthesis of proteins. According to the “ Sequence Hypothesis,” Crick wrote that the specificity of a segment of DNA “is expressed solely by the sequence of bases,” and “this sequence is a (simple) code for the amino acid sequence of a particular protein.” Crick further proposed that DNA controls protein synthesis through the intermediary of RNA, arguing that “the transfer of information from nucleic acid to nucleic acid, or from nucleic acid to protein may be possible, but transfer from protein to protein, or from protein to nucleic acid, is impossible.” Under some circumstances RNA might transfer sequence information to DNA, but the order of causation is normally “DNA makes RNA makes protein.” Crick called this the “ Central Dogma” of molecular biology [3], and it is sometimes stated more generally as “DNA makes RNA makes protein makes us.”

The Sequence Hypothesis and the Central Dogma imply that only protein-coding DNA matters to the organism. Yet by 1970 biologists already knew that much of our DNA does not code for proteins. In fact, less than 2% of human DNA is protein-coding. Although some people suggested that non-protein-coding DNA might help to regulate gene expression, the dominant view was that non-protein-coding regions had no function. In 1972, biologist Susumu Ohno published an article wondering why there is “so much ‘ junk’ DNA in our genome” [4].
  1. Crick published a Nature paper on The Central Dogma of Molecular Biology in 1970. Did he and most other molecular biologists actually believe that "only protein-coding DNA matters to the organism?"
  2. Did Crick really say that "DNA makes RNA makes protein" is the Central Dogma or did he say that this was the Sequence Hypothesis? Read the paper to get the answer—the link is below).
  3. Is it true that, in 1970, the majority of molecular biologists did not believe in repressor and activator binding sites (regulatory DNA)?
  4. Is it true that in 1970 molecular biologists knew nothing about the functional importance of non-transcribed DNA sequences such as centromeres and origins of DNA replication?
  5. It is true that most molecular biologists in 1970 had never heard of genes for ribosomal RNAs and tRNAs (non-protein-coding genes)?
  6. If the answer to any of those questions contradicts what Jonathan Wells is saying then why do you suppose he said it?

Crick, F. (1970) Central Dogma of Molecular Biology. Nature 227:561-563. [PDF]

Wednesday, August 21, 2013

Goodbye Copenhagen

We've been in Copenhagen for a few days but today is the last day of our vacation. We fly to Iceland and Toronto in a few hours.



Sunday, August 18, 2013

Saint Petersburg

Here are some photos of Saint Petersburg. I was happy to visit the cruiser Aurora in the Neva river. I first read about its role in the Russian revolution when I was in high school.

The fourth photo shows a typical street scene in the city. You should be able to translate the sign (СТОП) under the stop lights if you were paying attention to my post from a few weeks ago.


Saint Petersburg: Hermitage Museum

The highlight of our Baltic cruise was the visit to Saint Petersburg, Russia. We hired a guide and driver to take us around to the various sites in Saint Petersburg and the outskirts. The Hermitage (Зрмитаж) museum is located on the banks of one of the main channels of the Neva river (Болъшая Нева). The first photo shows a view form across the river.

This is the old winter palace of the Russian Czars so the building itself is part of the history—like the Louvre in Paris.

The second photo is one of the spectacular views from inside the museum. Everyone says that you really need three days to see everything and I agree. However, our guide took us on a brief tour of the major highlights so we got a good impression in just three hours.

The last photo shows us getting into our van at the end of the visit. If you look closely, you’ll see the name of Ms. Sandwalk’s blog on the dashboard (click to embiggen).



A Rainy Day in Helsinki

We visited Helsinki, Finland, a few days ago (August 14, 2013). It was a rainy day. We spent most of our time shopping and walking around the old town.


Wednesday, August 14, 2013

Stockholm: Old Town

We visited Stockholm yesterday and toured the city with my cousin Sharon and her husband Dennis. (That’s them with Ms. Sandwalk in the third photo.) Here are some photos of the Old Town including one of the Swedish Academy where I tried to put in a good word for all my readers.


45 Years Ago

We're celebrating our 45th wedding anniversary by taking a cruise in the Baltic. We were in Oslo, Norway on our anniversary day (August 9) where we met our friends Dag and Robin from graduate student days. They are als0 marride 45 years so we celebrated with champagne at their house. More about that later.




Monday, August 12, 2013

University of Rostock

The University of Rostock was founded in 1419. It’s said to be the oldest university in the Baltic Sea area. The main university building is a prominent landmark in Rostock but I was more interested in the Zoology building off to the side.

Looks like I just missed an important conference. Does everyone know who Willi Hennig is?



Warnemünde and Rostock

Yesterday our boat stopped at the habor in Warnemünde, Germany. There was a lot of activity of the quay in Warnemünde because a number of tall ships were in the harbor.

We took the train to the medieval town of Rostock—a key port in the Hansiatic League (Hansa=guilds). The architecture was similar to that in other leading cities of the Hansiatic League, notably Bruges.



Sunday, August 11, 2013

Cruising

We've been on this boat for three days and we'll be on it for another 8 days as we cruise the Baltic Sea. Internet access costs 70 cents ($0.75 US) per minute so posts will be short and infrequent.




Friday, August 09, 2013

Wednesday, August 07, 2013

Carnival of Evolution #62: The Whig History

The latest issue of Carnival of Evolution is hosted by Joachim D, an evolutionary ecologist who blogs at Ecology and Evolution Footnotes. Read: Carnival of Evolution 62: The Whig History .
When it comes to the history of evolutionary theory, a whiggish image could look something like [the figure below]

I leave it to the readers to come up with a female version (including, for example, Maria Sibylla Merian, Rosalind Franklin, Barbara McClintock, Christiane Nüsslein-Volhard).

Arranging July's posts that I found interesting or entertaining as well as the few submitted by others according to a Whig history of evolutionary theory in the following is purely ornamental and does, of course, not imply any whiggishness on the side of the contributors.


If you want to host a Carnival of Evolution please contact Bjørn Østman. Bjørn is always looking for someone to host the Carnival of Evolution. He would prefer someone who has not hosted before but repeat hosts are more than welcome right now! Bjørn is threatening to name YOU as host even if you don't volunteer! Contact him at the Carnival of Evolution blog. You can send articles directly to him or you can submit your articles at Carnival of Evolution although you now have to register to post a submission. Please alert Bjørn or the upcoming host if you see an article that should be included in next month's. You don't have to be the author to nominate a post.

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Tuesday, August 06, 2013

Carnival of Evolution #61: Crustie Lovin; Edition

I was out of town when the last two Carnivals of Evolution were published so I'm doing a bit of catchup. The July issue of Carnival of Evolution was hosted by Marc Srour at Teaching Biology. He's the only blogger I know who is based in Cyprus. (He may have just moved to Japan.) Read: Carnival of Evolution #61: Crustie Lovin; Edition.
Hello, and welcome to the Carnival of Evolution #61. For this edition, I’ve chosen to celebrate what I perceive as an inexplicably underappreciated group of animals: the Crustacea. Of the major arthropod groups, I notice that crustaceans often get the short end of the stick. Everyone can name insects and recognise spiders, but besides seafood, crustaceans seem to be a question mark with most people. Insects and spiders have movies and songs written about them; crabs are the logo for cancer, the vernacular name for an STD, and they are an astrological sign.

Insulting. Crustaceans are awesome. There may be over a million insect species, but crustaceans take the cake when it comes to disparity, or morphological diversity, a measure in which no other taxon can match them.

If you want to host a Carnival of Evolution please contact Bjørn Østman. Bjørn is always looking for someone to host the Carnival of Evolution. He would prefer someone who has not hosted before but repeat hosts are more than welcome right now! Bjørn is threatening to name YOU as host even if you don't volunteer! Contact him at the Carnival of Evolution blog. You can send articles directly to him or you can submit your articles at Carnival of Evolution although you now have to register to post a submission. Please alert Bjørn or the upcoming host if you see an article that should be included in next month's. You don't have to be the author to nominate a post.

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Monday, August 05, 2013

Carnival of Evolution #60: Party like it’s 1953

I was out of town when the last two Carnivals of Evolution were published so I'm doing a bit of catchup. The June issue of Carnival of Evolution was hosted by Zen Faulkes at NeuroDojo. He's a invertebrate neuroethologist, whatever that is. Read: Carnival of Evolution #60: Party like it’s 1953.
Ladies and gentlemen, this is a special edition of the Carnival of Evolution. It’s the big six oh!

In honor of that achievement, we shall share this carnival’s space with other events celebrating their sixtieth anniversary.


If you want to host a Carnival of Evolution please contact Bjørn Østman. Bjørn is always looking for someone to host the Carnival of Evolution. He would prefer someone who has not hosted before but repeat hosts are more than welcome right now! Bjørn is threatening to name YOU as host even if you don't volunteer! Contact him at the Carnival of Evolution blog. You can send articles directly to him or you can submit your articles at Carnival of Evolution although you now have to register to post a submission. Please alert Bjørn or the upcoming host if you see an article that should be included in next month's. You don't have to be the author to nominate a post.

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Monday's Molecule #212

Last week's molecule was a thymine dimer. The winners were Alex Ling and Matt McFarlane. [Monday's Molecule #211].

Today's molecule is an important part of a major pathway. Give the common name and identify the pathway. Explain briefly why this pathway is important.

Email your answers to me at: Monday's Molecule #212. I'll hold off posting your answers for 24 hours. The first one with the correct answer wins. I will only post the names of people with mostly correct answers to avoid embarrassment. The winner will be treated to a free lunch.

There could be two winners. If the first correct answer isn't from an undergraduate student then I'll select a second winner from those undergraduates who post the correct answer. You will need to identify yourself as an undergraduate in order to win. (Put "undergraduate" at the bottom of your email message.)