Time to Re-write the Textbooks: RNA has a Fifth Base!!!

From Science Daily via a press release from NewYork-Presbyterian Hospital/Weill Cornell Medical Center/Weill Cornell Medical College: RNA Modification Influences Thousands of Genes: Revolutionizes Understanding of Gene Expression.

Over the past decade, research in the field of epigenetics has revealed that chemically modified bases are abundant components of the human genome and has forced us to abandon the notion we've had since high school genetics that DNA consists of only four bases.

Now, researchers at Weill Cornell Medical College have made a discovery that once again forces us to rewrite our textbooks. This time, however, the findings pertain to RNA, which like DNA carries information about our genes and how they are expressed. The researchers have identified a novel base modification in RNA which they say will revolutionize our understanding of gene expression.

Their report, published May 17 in the journal Cell, shows that messenger RNA (mRNA), long thought to be a simple blueprint for protein production, is often chemically modified by addition of a methyl group to one of its bases, adenine. Although mRNA was thought to contain only four nucleobases, their discovery shows that a fifth base, N6-methyladenosine (m6A), pervades the transcriptome.

Those who don't know history are destined to repeat it.

Edmund BurkeWe've known about modified bases in DNA since the early 1970s so there aren't any modern textbooks that don't mention them. If your high school genetics course didn't mention modified bases it isn't because scientists didn't know of their existence—unless, of course, you graduated from high school more than forty years ago.

We've known about the presence of N⁶-methyladenosine in mRNA for several decades. Here's the introduction to a 1984 paper by Horowitz et al. (1984).

The most prevalent internal methylated nucleoside in eukaryotic mRNA is N6-methyladenosine (m6A). This modified nucleoside is found in RNAs of higher eukaryotic organisms (1-6), plants (7-9), and viruses (3, 10-12), and occurs at two specific sequences: Gpm6ApC and Apm6ApC (13-17).

Refereences 1-5 are from 1975 meaning that in the published scientific literature the presence of m6A dates back 37 years. That's more than enough time to make it into the textbooks. It's in the textbooks.

Not only that, textbooks also contain references to two other modified bases in mRNA. N⁷-methylguanylate is common in cap structures and several mRNAs are known to contain inosine (I), a modified form of adenylate.

I blame the science writers at Cornell Medical Center for writing something that is not true and I blame the authors of the paper for hype and exaggeration and for not correcting the press release before it was published. That's not how science is supposed to work.

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[Hat Tip: Uncommon Descent: Is there a fifth base in RNA?]

Horowitz, S., Horowitz, A., Nilsen, T.W., Munns, T.W. and Rottman, F.M. (1984) Mapping of N6-methyladenosine residues in bovine prolactin mRNA. PNAS 81:5667-5671. [PDF]

Advice for High School Graduates

The Chicago Tribune has an opinion piece on Open letter to high school grads. You really should read the entire thing but here's part of it ...

If you haven't posted a good academic performance in high school, don't believe a university, its leadership, advertisements or admissions officers who co-sign your promissory note with no responsibility for its payment obligation. They need paying students.

Stoking a deceitful dream on life support — an underappreciated, overfinanced, media-hyped charade — is the real deception, and the weight falls on your back, not theirs.

A shameful, elaborate sham, when one out of two college graduates this year are unemployable in their chosen field.

Look carefully at the costs and benefits of a university education. University officials may not tell you the truth: Enrollments could drop. Bankers will not tell you the truth: Interest income will fall off. Elected officials will not tell you the truth: Elections will be lost. Listen to those really concerned for you carefully.

Who wrote this? It's Walter V. Wendler, who is listed as director of the School of Architecture and former chancellor at Southern Illinois University.

On the Significance of Student Evaluations

I been interested in the efficacy of students evaluations for a long time [Student Evaluations] [Student Evaluations] [Student Evaluations Don't Mean Much].

There's an extensive pedagogical literature on the issue [Student Evaluations: A Critical Review] [New Research Casts Doubt on Value of Student Evaluations of Professors] [Does Professor Quality Matter? Evidence from Random Assignment of Students to Professors] [Evaluating Methods for Evaluating Instruction: The Case of Higher Education] [Of What Value are Student Evaluations?] [Why Student Evaluations of Teachers are Bullshit, Some Sources ].

Much of this literature points out what is obvious to any university instructor; students evaluations are not very good at measuring teaching effectiveness.

All IDiots Believe in Evolution!

The title of this post may shock you but bear with me for a minute. I've been trying for years to educate creationists on the meaning of evolution and the strawman term "Darwinism." I've pointed out repeatedly that the the standard minimal definition of evolution ("Evolution is a process that results in heritable changes in a population spread over many generations") should be perfectly acceptable to any IDiot. They don't really reject all of evolution, just the part that causes particular problems for their religion.

Finally, we have an Intelligent Design Creationist who is willing to take the bull by the horns and point out the obvious. Johnnyb explains how his fellow IDiots should think about evolution [How to Talk to Your Professors About Your Darwin Doubts].

So what is one to do? Well, thankfully, our friends the evolutionists have given us a way out. In their zeal to claim consensus on the “fact of evolution,” they have had to steamroll together such a large diversity of opinion into the single term “evolution”, that the word “evolution” no longer has the grand meaning it used to. The only real meaning everyone can agree on is “change in allele frequency over time” – and that is a definition that literally everyone can agree with.

In other words, even if you are a young earth creationist, if your professor asks if you believe in evolution, the legitimate answer is “yes”. Given the common definition of “evolution,” the only thing they are really asking with that question is, “do you believe in genetics?”

Therefore, here is how you can, and, I say, should frame yourself – you believe in evolution. However, there are a few parts of the theory that you disagree with. Don’t be obnoxious, but don’t be overly shy either. Just be frank. Do you believe in evolution? “Yes, but I disagree that common ancestry is universal.” Do you believe in evolution? “Yes, but I don’t think that natural selection alone as a mechanism sufficiently explains life’s diversity.” You don’t even have to put the “yes” and the objection in the same sentence. What do you think about evolution? “The study of evolution is fascinating!” How do you think multicellularity evolved? “I think that multicellularity is a fundamental property of certain organisms, and can’t be evolved piecemeal from the presumed single-celled ancestors.” But you do believe in evolution? “Yes, of course.” Do you think multi-cellular organisms evolved? “Certainly!” From what? “Other multi-cellular organisms.”

If someone challenges you on the definition of evolution, simply challenge them back. What definition of evolution are you using? “I’m using the standard population genetics definition of evolution as the change in gene frequencies over time.” That’s not what evolution is. “What is your definition of evolution?” Evolution means natural selection and common ancestry! “Well, that’s a pretty narrow view of evolution in modern biology. So, while I agree with evolution in general, I don’t agree with your specific view of it.” What’s your specific view? “I’m still learning! But I do find it interesting that….[put your favorite evolutionary or non-evolutionary feature of biology here]”

Let's see how many of his fellow creationists take this advice to heart. Are you listening Denyse?

I'm willing to bet that the vast majority will still never admit that evolution, as defined, is a fact because we can directly observe it happening right before our eyes.

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David Klinghoffer Will Bust Your Mark VIII Irony Meter

Back in the days of newsgroups (last century) the howlers in talk.origins developed a running joke about irony meters.

The lastest version (Mark VIII) is pretty sturdy but from time to time the IDiots come up with a real challenge. You might want to turn off your irony meter before reading any further and especially before following the link.

Here's David Klinghoffer's latest posting on the "prestigious" IDiot site, Evolution News & Views [What Is It about Professors and Reading Comprehension?].

How is it that many professors in the humanities and the sciences seem unable to read an opinion they don't like and then accurately relate the argument -- say it back to their interlocutor -- before trying to rebut it? This is a basic skill in communication that comes in handy in many areas of life, including personal relationships

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The Problem with Psychology

Ed Yong of Not Exactly Rocket Science has just published a scathing criticism of the entire field of psychology [Replication studies: Bad copy]. The fact that this article appears in Nature should be of great concern to all psychologists. Here's the two opening paragraphs.

For many psychologists, the clearest sign that their field was in trouble came, ironically, from a study about premonition. Daryl Bem, a social psychologist at Cornell University in Ithaca, New York, showed student volunteers 48 words and then abruptly asked them to write down as many as they could remember. Next came a practice session: students were given a random subset of the test words and were asked to type them out. Bem found that some students were more likely to remember words in the test if they had later practised them. Effect preceded cause.

Bem published his findings in the Journal of Personality and Social Psychology (JPSP) along with eight other experiments1 providing evidence for what he refers to as “psi”, or psychic effects. There is, needless to say, no shortage of scientists sceptical about his claims. Three research teams independently tried to replicate the effect Bem had reported and, when they could not, they faced serious obstacles to publishing their results. The episode served as a wake-up call. “The realization that some proportion of the findings in the literature simply might not replicate was brought home by the fact that there are more and more of these counterintuitive findings in the literature,” says Eric-Jan Wagenmakers, a mathematical psychologist from the University of Amsterdam.

There's lots more where that comes from. Read the entire article.

One of the most remarkable things about Ed Yong's paper is that he doesn't even mention evolutionary psychology! I think that the absurdity of most evolutionary psychology papers is more than sufficient reason to question whether the entire field is fatally flawed [Boobies and Evolutionary Psychologists].

There's clearly something wrong. Can it be possible that an entire discipline has gone off the rails?¹

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1. Saying that there's a problem with a discipline is not the same as saying that there's a problem with every single psychologist. What I'm saying is that the good psychologists don't seem to have the same influence that good biochemists and good evolutionary biologist (mostly) have on their respective disciplines.

Cellphones in the Classroom

Here's an interesting video clip on the advantages (?) of encouraging students to use cellphones in the classroom.


Students have been using laptops in my classes for more than a dozen years. They were never using them for the sole purpose of taking notes, especially since the installation of WiFi. Smart phones don't change anything.

If you teach a class that engages students and gets them to debate and discuss the issues then they won't have time to live tweet or do anything else on their smart phones. If you are teaching difficult and challenging concepts and principles, then you are likely to keep their attention. If you teach a class that allows students to busy themselves with lots of other tasks during the lecture, and still get a good grade, then they will do that.

I pose the following question ... if your students can spend a considerable amount of time using their smart phones during class then they are not giving the class their full attention. Are you teaching effectively?

And whatever happened to note-taking? How can you take notes with a smart phone in your hand? Is taking notes an old fashioned concept that should be abandoned?

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On Changing Education Because It's What the Students Want

In a previous post I mentioned an article by Sidneyeve Matrix who advocates changing the "traditional" form of undergraduate university education by incorporating more technology [Challenges, Opportunities, and New Expectations]. In that post, I concentrated on one of the arguments for online courses [On the Quality of Online Courses].

In this post I want to bring up one of the arguments for introducing new technology into a course. I'm going to pick a quote from Sidneyeve Matrix's article but she's not the only one who brings it up.

There’s a torrent of research demonstrating the costs and benefits of using social, mobile, and digital technology enhancements to teach; yet it’s inconclusive whether these result in higher student outcomes. Of course, there are multiple bottom lines to consider. What’s undeniable is that even though digital divides exist, today’s students expect to see some technology used in their classes. It follows that we can expect increased engagement and higher student satisfaction when profs power-up. In my experience, exceedingly positive end-of-term student surveys and reviews in my ed-tech enhanced courses document a beneficial halo effect.

The first statement is true, as far as I know. There are no sound pedagogical reasons for incorporating social media and other technologies into a course. That means there must be other, not-pedagogical, reasons for change.

The third statement says that it's "undeniable" that students expect to see some technology in their class. What does this mean? Will they be satisfied if they see a power point presentation and a website? Do they expect their professors to befriend them on facebook or follow their tweets? We don't know. The statement is devoid of meaning.

However, what seems to be "undeniable" is that there are some professors who think that it's important to give students whatever they want. These professors seem to think that it's the students, not them, who are the experts on undergraduate education. Is there any evidence for that?

Of course not. The reason for giving students what they want is clearly spelled out in the last sentence. If you give them what they want then you'll get good student evaluations.

In fairness, she also mentions "engagement." If student engagement is one of your goals—it's one of mine—then that's a reason for exploring technology options. That may, or may not, be associated with student satisfaction. My experience suggests that it's not. I first started an online discussion forum for students in 1987-88 using a usenet forum running on a VAX. Very few students used it but the ones who did liked it a lot.

Over the last 25 years, I've tried various ways of encouraging student engagement on the internet including, in the last iteration, trying to get students to read and comment on blogs. The result is always the same. A subset of the class has a great time "engaging" and a larger subset resists all attempts to draw them in. The most effective way to encourage, and reward, engagement is to do it in class with the students right there with you. The downside is that a good chunk of your class are miserable because they don't want to "engage" in their own learning. They would rather be passive learners.

In order for professors to engage in podcasting or online lectures or tweeting, or supporting their colleagues who opt to publish in open source journals or participate in online conferences, they must see real benefits and an immediate, significant return on investment. Perhaps for some profs evidence of increased student satisfaction and engagement will win them over.

I hope that "increased student satisfaction" will never be a primary motive for change. It may be a secondary benefit but that's not the same thing. Our job is to teach effectively. If the proper teaching methods don't "please" the students then our job is to convince them that they need to change their minds about what gives them pleasure. If they can't do that then they might have only two choices: (1) be miserable throughout their stay in university, or (2) drop out.

Option three: (3) make the professor change the course in order to cater to the student's view of how a course should be taught, is not a reasonable option.

Many of these debates and discussions about the use of new technology in the classroom assume that there's resistance from old professors who are uncomfortable with new technology and/or social media. That may be true of some professors but many of my mature colleagues have been computer literate since before many young professors were born. Many of my colleagues have been using email for thirty years. They have had webpages, including course webpages, since the web was created twenty years ago. In spite of the fact that they are not intimidated by technology—what science professor is intimidated by new technology?—they have not radically transformed their way of teaching in the past several decades. Why is that? Is it because they have the wisdom and experience to know that new technology is not the best way to improve undergraduate education?

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On the Quality of Online Courses

Are online courses a good thing, a bad thing, or relatively neutral? There's much to debate.

The main issue, as far as I'm concerned, is pedagogical. Are online courses a good way to teach critical thinking—the primary goal of undergraduate education?

There are tangential issues that often get in the way of dealing with the important questions and I'd like to deal with one of them here.

In a previous post [Is Canada Lagging Behind in Online Education?] I criticized a newspaper article by Michael Geist because he made an incorrect assumption. He assumed that any online course from a "top-tier" university would be serious competition for the average Canadian school. I selected two courses from MIT and showed that the quality of their biochemistry teaching was not a threat.

This point needs to be emphasized. Just because an online undergraduate course comes from Harvard, MIT, or Stanford does not mean that it's a good quality course. In my own field of biochemistry I know of many, many teachers in small schools throughout North America who can teach biochemistry better than famous research professors at the so-called "top-tier" schools.

It still may be true that students will flock to the Harvard, MIT, and Stanford courses and pay those schools for biochemistry credits but let's not assume, without justification, that they are getting a better education.

Today I received a copy of Academic Matters: OCUFA's Journal of Higher Education, a magazine published by the Ontario Federation of University Faculty Associations (OCUFA). The articles are devoted to technology in the classroom ("Professor 2.0." ugh!). An article by Sidneyeve Matrix [Challenges, Opportunities, and New Expectations] caught my eye. She says,

When Stanford University offers massively open online courses (MOOCs) in science and engineering, in one case drawing over 150,000 participants, people take notice. When the Khan Academy wins significant Microsoft funding, posts 3,000 instructional videos online, and attracts massive traffic, stories proliferate about the future of self-directed, online, informal e-learning. ... Critics ask, what’s the value of having students attend a lecture in real time if essentially the same material is covered by world-renowned professors on professional-quality video courtesy of free services at TED-Ed or YouTube Education? ... Why pay enormous fees to learn from faculty in an accredited university program, when MITx offers free online courseware with options for students to get peer-to-peer and professor feedback, assessment and earn branded certificates of achievement? What is the return on investment for students (and perhaps their parents) opting to earn their credentials at a bricks-and-mortar university when they could join the 30,000 others enrolled at the London School of Business and Finance in their Global MBA program—delivered online via a Facebook app?

There's a myth here that needs exposing. The quality of undergraduate education in the sciences¹ should be judged by the content of the course and not the prestige of the university that offers it. Let's not get bamboozled into thinking that just because Stanford and Khan University Academy offer an online course in biochemistry that it's necessarily a good course.

The MIT examples I highlighted in my previous post says that this is a a bad assumption. You can look at the Stanford University Courses and make up your own mind.

Here's the important point: don't just assume that because an online course exists, it is necessarily a good course. You may have legitimate reasons for thinking that online courses are good things, but that doesn't excuse you from actually looking at the quality of an online course before declaring that the producers of such a course did a good job. Putting a bad course online is worse than putting no course online no matter what you might think of online courses.

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1. I restricted myself to the sciences because we are presumably judging quality by the ability to teach critical thinking and factually correct material. There may well be degrees and programs where this isn't important. For example, it may not be important who teaches MBA courses since the goal is just to get a degree to put on your CV. In that case the prestige of the London School of Business and Finance may be far more important than whether you are actually learning something useful, or correct.

Michael Richards on the Sandwalk

Technically, this isn't Michael Richards on the Sandwalk but I'm posting it anyway. He sent me this drawing from a recent visit. It's the same view as in the Steve Watson and Seanna Watson photos (links are below). Thanks Michael.

Larry Moran
PZ Myers
John Wilkins
Ryan Gregory
The God Delusion
Cody
John Hawks
Michael Barton
Seanna Watson
Steve Watson
Michael Richards

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Next Generation Science Standards: Evolution

Next Generation Science Standards is an organization dedicated to developing new K12 science standards for schools in the United States. The partners are the American National Research Council, The American Association for the Advancement of Science (AAAS), The National Science Teachers Association (NSTA), and Achieve, a nonprofit education reform organization.

The draft standards are posted on the website and you are invited to make comments until June 1st. Let's see what the new standards have to say about teaching evolution.

Here's what should be taught in middle school.

LS4.A: Evidence of Common Ancestry and Diversity

• Fossils are mineral replacements, preserved remains, or traces of organisms that lived in the past. Thousands of layers of sedimentary rock not only provide evidence of the history of the Earth itself but also of changes in organisms whose fossil remains have been found in those layers. (a)
• The collection of fossils and their placement in chronological order (e.g., through the location of the sedimentary layers in which they are found or through radioactive dating) is known as the fossil record. It documents the existence, diversity, extinction, and change of many life forms throughout the history of life on Earth. Because of the conditions necessary for their preservation, not all types of organisms that existed in the past have left fossils that can be retrieved. (c)
• Anatomical similarities and differences between various organisms living today, and between them and organisms in the fossil record, enable the reconstruction of evolutionary history and the inference of lines of evolutionary descent. (b)
• Comparison of the embryological development of different species also reveals similarities that show relationships not evident in the fully-formed anatomy. (d)

LS4.B: Natural Selection

• Genetic variations among individuals in a population give some individual an advantage in surviving and reproducing in their environment. This is known as natural selection. It leads to the predominance of certain traits in a population, and the suppression of others. (e),(f)

LS4.C: Adaptation

• Adaptation by natural selection acting over generations is one important process by which species change over time in response to changes in environmental conditions. (g)
• Traits that support successful survival and reproduction in the new environment become more common; those that do not become less common. Thus, the distribution of traits in a population changes. (f)
• In separated populations with different conditions, the changes can be large enough that the populations, provided they remain separated (a process called reproductive isolation), evolve to be separate species. (g)

Not bad, all things considered. I'd like to add that some evolution occurs by the chance increase in certain traits in a population, a process known as random genetic drift. Drift is part of the standards in my province of Ontario.

I'd also like to delete "in response to changes in environmental conditions" and "in the new environment" from LS4.C. The idea that natural selection only occurs when the environment changes is a common misconception and there's no reason to perpetuate that misconception.

Here are the high school standards.

LS4.A: Evidence of Common Ancestry and Diversity

• Genetic information, like the fossil record, also provides evidence of evolution. DNA sequences vary among species, but there are many overlaps; in fact, the ongoing branching that produces multiple lines of descent can be inferred by comparing the DNA sequences of different organisms. Such information is also derivable from the similarities and differences in amino acid sequences and from anatomical and embryological evidence. (e)

LS4.B: Natural Selection

• Natural selection occurs only if there is both (1) variation in the genetic information between organisms in a population and (2) variation in the expression of that genetic information—that is, trait variation—that leads to differences in performance among individuals. (a),(c)
• The traits that positively affect survival are more likely to be reproduced, and thus are more common in the population. (b),(c),(d),(f)

LS4.C: Adaptation

• Natural selection is the result of four factors: (1) the potential for a species to increase in number, (2) the genetic variation of individuals in a species due to mutation and sexual reproduction, (3) competition for an environment’s limited supply of the resources that individuals need in order to survive and reproduce, and (4) the ensuing proliferation of those organisms that are better able to survive and reproduce in that environment. (a)
• Natural selection leads to adaptation, that is, to a population dominated by organisms that are anatomically, behaviorally, and physiologically well suited to survive and reproduce in a specific environment. That is, the differential survival and reproduction of organisms in a population that have an advantageous heritable trait leads to an increase in the proportion of individuals in future generations that have the trait and to a decrease in the proportion of individuals that do not. (b),(c),(f)
• Adaptation also means that the distribution of traits in a population can change when conditions change. (d)
• Changes in the physical environment, whether naturally occurring or human induced, have thus contributed to the expansion of some species, the emergence of new distinct species as populations diverge under different conditions, and the decline–and sometimes the extinction–of some species. (d)
• Species become extinct because they can no longer survive and reproduce in their altered environment. If members cannot adjust to change that is too fast or drastic, the opportunity for the species’ evolution is lost. (d)

I have more of a problem with the high school standards. High school students must learn about random genetic drift, especially if they are comparing sequences since most of the changes they will see are nearly neutral changes that have been fixed by drift.

I think the standards should specifically mention that selection can occur in a constant environment since no organisms are perfectly adapted.

I hope the standards include specific attention to the relationship between humans and other species as shown by the combination of sequence comparisons, anatomical similarities, and the fossil record.

The source of mutations is covered in another section (LS3.B).

It would be nice to describe the differences between the fact of evolution and evolutionary theory.

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Monday's Molecule #170

This is a rather unusual molecule that I suspect most of you are unfamiliar with. You need to identify the molecule (correct trivial name will do). I also want you to identify the most important enzyme that uses this molecule as a substrate in the normal direction of flux. Describe the dominant symptom of patients who can't make this enzyme.

Post your answers as a comment. I'll hold off releasing any comments for 24 hours. The first one with the correct answers wins. I will only post mostly correct answers to avoid embarrassment. The winner will be treated to a free lunch.

There could be two winners. If the first correct answer isn't from an undergraduate student then I'll select a second winner from those undergraduates who post the correct answer. You will need to identify yourself as an undergraduate in order to win. (Put "undergraduate" at the bottom of your comment.)

Some past winners are from distant lands so their chances of taking up my offer of a free lunch are slim. (That's why I can afford to do this!)

In order to win you must post your correct name. Anonymous and pseudoanonymous commenters can't win the free lunch.

Winners will have to contact me by email to arrange a lunch date.

Comments are invisible for 24 hours. Comments are now open.

UPDATE: The molecule is 4α-carbinolamine, one of the products of the phenylalanine hydroxylase reaction. 4α-Carbinolamine is transformed into 5,6,7,8-tetrahydrobiopterin in two steps. In the first step it is the substrate for 4α-carbinolamine dehydratase. Mutations in that enzyme cause a mild form of phenylketonuria that usually has no serious consequences for the patient.

There are no winners this week.

Winners
Nov. 2009: Jason Oakley, Alex Ling
Oct. 17: Bill Chaney, Roger Fan
Oct. 24: DK
Oct. 31: Joseph C. Somody
Nov. 7: Jason Oakley
Nov. 15: Thomas Ferraro, Vipulan Vigneswaran
Nov. 21: Vipulan Vigneswaran (honorary mention to Raul A. Félix de Sousa)
Nov. 28: Philip Rodger
Dec. 5: 凌嘉誠 (Alex Ling)
Dec. 12: Bill Chaney
Dec. 19: Joseph C. Somody
Jan. 9: Dima Klenchin
Jan. 23: David Schuller
Jan. 30: Peter Monaghan
Feb. 7: Thomas Ferraro, Charles Motraghi
Feb. 13: Joseph C. Somody
March 5: Albi Celaj
March 12: Bill Chaney, Raul A. Félix de Sousa
March 19: no winner
March 26: John Runnels, Raul A. Félix de Sousa
April 2: Sean Ridout
April 9: no winner
April 16: Raul A. Félix de Sousa
April 23: Dima Klenchin, Deena Allan
April 30: Sean Ridout
May 7: Matt McFarlane
May 14: no winner

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Is Canada Lagging Behind in Online Education?

"Is Canada lagging behind in online education?" is the title of an article in today's Toronto Star. The title in the print edition is "Education not evenly distributed."

The author is Michael Geist who is described as follows ...

Michael Geist is a law professor at the University of Ottawa where he holds the Canada Research Chair of Internet and E-commerce Law. He has a Bachelor of Laws degree from Osgoode Hall Law School in Toronto, Master of Laws degrees from Cambridge University in the UK and Columbia Law School in New York, and a Doctorate in Law from Columbia.

Hmmm ... that's interesting. A lawyer with no obvious expertise in education is writing about education. Let's see what he has to say ...

... in recent weeks it has become increasingly clear that the future of education is here, though it is not evenly distributed. The emerging model flips the current approach of expensive textbooks, closed research, and limited access to classroom-based learning on its head, instead featuring open course materials, open access to scholarly research, and Internet-based courses that can simultaneously accommodate thousands of students. The concern is that other countries are becoming first adopters, while Canada lags behind.

Multi Faith Room Disappears!!

I forwarded a link to my blog post [Look What Just Appeared Right Beside My Office!!!] to the Dean of the Faculty of Medicine. Less than 24 hours later the sign has been removed, the furniture taken away, and the door is locked.

I'm pretty sure the Dean is behind this. As soon as she learned about it, she recognized that someone had done something inappropriate (i.e. stupid). We'll probably never learn who was responsible but I thank the Dean for taking care of the problem so quickly.

This is just one more in a long list of good things she has done recently. We are lucky to have her as Dean.

Now, if only she had a better staff in the Dean's Office ....

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Non-Negotiables of Darwinism

For the sake of completeness, I thought I'd include the basic tenets of Darwinism as outlined by Bill Dembski in his BioLogos essay: Southern Baptist Voices: Is Darwinism Theologically Neutral?.

Non-Negotiables of Darwinism:

• (D1) Common Descent: All organisms are related by descent with modification from a common ancestor.
• (D2) Natural Selection: Natural selection operating on random variations is the principal mechanism responsible for biological adaptations.
• (D3) Human Continuity: Humans are continuous with other animals, exhibiting no fundamental difference in kind but only differences in degree.
• (D4) Methodological Naturalism: The physical world, for purposes of scientific inquiry, may be assumed to operate by unbroken natural law.

My question is for any scientist who defines themselves as a Darwinist. Do you agree with these non-negotiables? Are there any you would like to add or modify?

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