A physicist tries to understand junk DNA

Rob Sheldon has a PhD. in physics and a M.A. in religion.¹ With two strikes against him already, he attempts to understand biology by discussing evolution, junk DNA, and the Onion Test [Physicist suggests: “Onion test” for junk DNA is challenge to Darwinism, not ID]. As you might imagine, posting on Uncommon Descent in support of Intelligent Design Creationism leads directly to strike three.

The Onion Test was created by Ryan Gregory in 2007 [The Onion Test] and published in the scientific literature by Palazzo and Gregory in 2014. It goes like this. Take your favorite hypothesis suggesting that most of the DNA in the human genome is functional and use it to explain why the onion, Allium cepa, needs a genome that is five times larger than the human genome. Then explain why closely related species of onion need twenty times more DNA than humans.

Learn to think like a scientist

There's a course at MIT (Boston, USA) called "7.00x Introduction to Biology - The Secret of Life." It's a very popular MOOC (online course). Here's the trailer for the course. In it, Eric Lander tells you that if you take his introductory biology course you will learn to think like a scientist and you will be able to understand the latest breakthroughs.


Here are the week one lectures that focus on biochemistry. I don't have time to go through it all but check out the description of ATP beginning at 2:13. This is not how good teachers explain the importance of ATP in the 21st century but it is how it was taught 40 years ago.

Get a job as a dissertation writer

Jerry Coyne has found a posting for a job in Toronto [see Dissertations for sale!]. You can see the original at: Dissertation Writers wanted for Work from Home Position. It's suitable for retired professors and post-docs who can't get any other job.

We are a medium sized, cloud-based consultancy headquartered in New York, but with consultants spread across the globe, from Asia to South America. We primarily handle Academic Consulting for Doctorate level clients, and we currently have several job openings in the Academic Research department.

Job responsibilities:
Your main responsibility will be to assist our clients in conducting the research needed needed to complete their theses, dissertations, or journal articles, and then writing drafts for portions of those documents, such as a Literature Review, Introduction or Discussion chapters.

The job will involve communicating with clients by email and by phone to understand their specific needs, provide suggestions on how to improve their research, and finally write a draft of the document itself. It will also involve engaging in ongoing discussions with clients after the first draft, and revising/rewriting the document to our clients' satisfaction.

*This is strictly a work-from-home position*, and any applicant should view this as a strong incentive.

Please note that this is a *full-time position*.

Requirements:
- Applicants must possess a meticulous nature and an extremely high attention to detail.
- A very positive and upbeat attitude (particularly as relates to phone calls and email communication with clients).
- Native English speakers only.
- A 4-year college degree is an absolute must, preferably from a well-known university.
- Ghostwriting or Technical Writing experience is desired, but not a must.
- Tutoring and/or research experience is also a bonus.

Compensation:
Compensation for the successful applicant is very generous. As we expect very few applicants to have directly applicable work experience in this field, there will be an extensive training program before the candidate is taken on in a more permanent capacity. Training will be paid, at USD 4,000/month, and is projected to last 3-4 months. Following successful training, pay will be USD 85,000 - USD 100,000/year.

I've chaired quite a few Ph.D. exams for humanities students and I reckon I could bang out a pretty good thesis in a few months.

As for journal articles, the ENCODE Consortium could hire me for $8000 per month.

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Here's a good example of a tenured professor who should be fired

I am a staunch defendant of academic freedom but tenure doesn't protect you from gross misconduct. Here's an example where a Professor of Philosophy at UNC faced dismissal hearings and, wisely, decided to resign. I'm betting that ethics wasn't her specialty.

Why did she resign? Read about it at: Jan Boxill, implicated in UNC scandal, resigns.

Apparently Boxill was counselor to the women’s basketball team and she participated in a scheme to give athletes decent grades in "courses" that didn't exist or required minimal work. Some of the courses were in African and Afro-American Studies (AFAM) and some were philosophy courses.

[The Provost's] letter to Boxill said there was "compelling evidence that over a period of several years you knowingly participated in grossly improper practices in your roles as a member of the faculty and an academic advisor to student athletes."

The letter, released Thursday, accused Boxill of several acts of misconduct:

▪ Requesting that AFAM employees provide specific grades to students.

▪ Steering athletes to AFAM courses that she knew were not overseen or taught by faculty, required only a paper and were graded by former office manager Deborah Crowder.

▪ Editing and writing portions of text inserted into the papers of the students she tutored.

▪ Allowing students to enroll in independent study classes in philosophy that required little academic work.

Bye-bye Boxhill.

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How to promote science according to new AAAS CEO Rush D. Holt

As the name implies, the American Association for the Advancement of Science (AAAS) is a group of American scientists dedicated to "advancing" science. It was formed in 1848 and over the years it has evolved into a sophisticated lobby for advocating and defending science funding as well as an organization that promotes science to the general public. It publishes several journals, including Science and Science: Translational Medicine.

The new CEO and Executive Publisher of Science is Rush D. Holt, Jr.. He is the son of a former United States Senator (Rush D. Holt Sr.). Rush D. Holt Jr. obtained a Ph.D. in physics in 1981 and taught courses in physics, public policy, and religion at Swarthmore College from 1980 to 1986. He is a Quaker.

Don't misuse the word "homology"

Here's the latest science news from The Allium": Evolutionist Loses It As Colleague Conflates Homology and Similarity Yet Again.

Evolutionary biologist Dr. Constance Noring shot and killed her microbiology colleague and formerly good friend, Dr. Dan Deline when, for the umpteenth time he used the word homology when he really should have said similarity.

Read the rest. I sympathize with Professor Noring. This could have been me if Canadians were allowed to buy handguns.

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C0nc0rdance reads from Dobzhansky defending accommondationism

Here's how COncOrdance explains his latest YouTube video.

To celebrate Darwin Day, Feb 12th, 2015, I offer the words of Dobzhansky, who was a central figure in the modern evolutionary synthesis with his 1937 book, "Genetics and the Origin of Species". Dobzhansky was also a deeply religious man who believed that God had a hand in the process of evolution, a view I don't share, but try to understand.

Dobzhansky cites Teilhard de Chardin, who was a biologist, a theistic evolutionist, and a controversial figure who described evolution as cosmic attainment of perfection, a concept I also strongly disagree with.

This is an excerpt from the original work:
The American Biology Teacher, Vol. 35, No. 3 (Mar., 1973), pp. 125-129. [Nothing in Biology Makes Sense except in the Light of Evolution]

I'm not sure what purpose is served by reading from Dobzhansky's book where he praises Pierre Teilhard de Chardin. Keep in mind that Teilhard's most famous book was reviewed by Peter Medawar who described it like this: "... the greater part of it, I shall show, is nonsense, tricked out with a variety of metaphysical conceits, and its author can be excused of dishonesty only on the grounds that before deceiving others he has taken great pains to deceive himself."

That's pretty much the consensus view of Teilhard these days. It's also pretty common to point out that science as a way of knowing conflicts with religion as a way of knowing in spite of what Dobzhansky said 46 years ago.

Here's the video ....

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Is most of our DNA garbage?

Carl Zimmer's article on junk DNA has appeared in the online edition of the New York Times magazine at: Is Most of Our DNA Garbage?.

Carl was in Toronto and Guelph last December gathering information for his article. You can see that Ryan Gregory is featured and my colleague Alex Palazzo gets quoted.

Here's a picture of us having dinner. That's Alex on the left, second from left is some old dude who everyone ignores, Ryan is next and Carl Zimmer is on the right.

Carl is still the best science journalist on the planet and I appreciate that he has alerted the public to a serious problem in genome studies. The general public has been snowed by the ENCODE publicity campaign and by naive journalists who have enthusiastically reported that junk DNA is dead.

It is not. The most knowledgeable scientists recognize that the issue is not settled. The very best ones () know that 90% of our genome is junk.

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Does talk.origins still exist?

Several people have asked recently if talk.origins still exists and if the TalkOrigins Archive is still functional. As it turns out, the current king of the talk.origins newsgroup (David Greig) is going to be here (my office) either today or in the next few days to upgrade the talk.origins server. The name of the server is "Darwin" and here's what it looks like (right).

Here's a link to the newsgroup: talk.origins. Here's a description from the Wikipedia article on talk.origins.

The first post to talk.origins was a starter post by Mark Horton, dated 5 September 1986.

In the early 1990s, a number of FAQs on various topics were being periodically posted to the newsgroup. In 1994, Brett J. Vickers established an anonymous FTP site to host the collected FAQs of the newsgroup. In 1995, Vickers started the TalkOrigins Archive web site as another means of hosting the talk.origins FAQs. It maintains an extensive FAQ on topics in evolutionary biology, geology and astronomy, with the aim of representing the views of mainstream science. It has spawned other websites, notably TalkDesign "a response to the intelligent design movement", Evowiki, and the Panda's Thumb weblog.

The group was originally created as the unmoderated newsgroup net.origins as a 'dumping ground' for all the various flame threads 'polluting' other newsgroups, then renamed to talk.origins as part of the Great Renaming. Subsequently, after discussion on the newsgroup, the group was voted to be moderated in 1997 by the normal USENET RFD/CFV process, in which only spam and excessive crossposting are censored. The moderator for the newsgroup is David Iain Greig (and technically Jim Lippard as alternate/backup).

The group is characterized by a long list of in-crowd jokes like the fictitious University of Ediacara, the equally fictitious Evil Atheist Conspiracy which allegedly hides all the evidence supporting Creationism, a monthly election of the Chez Watt-award for "statements that make you go 'say what', or some such.", pun cascades, a strong predisposition to quoting Monty Python and a habit of calling penguins "the best birds".

Apart from the fun, the group includes rebuttals to creationist claims.There is an expectation that any claim is to be backed up by actual evidence, preferably in the form of a peer-reviewed publication in a reputable journal. The group as a whole votes for a PoTM-award (Post of The Month), which makes it into the annals of TalkOrigins Archive.

I forgot about penguins being the best bird. The article forgot to mention Howler monkeys.

The University of Ediacara consists of many faculty members named Chris plus some others. There's only one permanent student, me.

I won't try to name all the alumni who are still active on the newsgroup or on blogs. I'll let them confess identify themselves in the comments if they dare.

Here's the link to the TalkOrigins Archive. It contains all kinds of information on the evolution/creation debate including all the rebuttals to any argument the creationists have ever made.

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Genomes and junk DNA

Here's your chance to hear about genomes and junk DNA from one of the world's leading experts. The seminar is at the University of Toronto (Toronto, Canada) in the Medical Sciences Building. It's on Wednesday, March 4th—only two days form today! The seminar room (Rm 2172) is right around the corner from Tim Hortons. Ryan is from the University of Guelph. How Canadian can you get, eh?

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The University of Toronto explains why it hosted an alternative medicine conference

I received a response from Bruce Kidd, the Principal of the University of Toronto at Scarborough on why his campus was hosting a conference on alternative medicine (see Is the University of Toronto promoting quackery and pseudoscience?). I had asked whether the university was officially involved in sponsoring the event.

Here is his complete response. He knows that I will post it on my blog.

Dear Professor Moran:

Thank you for your inquiry. The University encourages the fullest, critical investigation of scientific and social issues, including the bases of health and well-being and the various ways personal, community and environmental health can be maintained and strengthened. That is an essential part of our institutional mission. As you know, we have been debating whose knowledge counts, the methodological bases for such knowledge and the professional practices that have been developed as a result of such knowledge in the field of health for many years. That's how knowledge advances. The hosting of the Population Health and Policy Conference at UTSC yesterday was just one expression of that commitment to critical inquiry.

That being said, such hosting cannot be equated with endorsement of the various positions and points of view expressed at the conference. I have attended hundreds of conferences at U of T and other universities over the years and have never felt that the presentation of particular views meant that the hosting institution endorsed those particular views.

I hope that's helpful.

With best wishes,

Bruce Kidd, O.C., Ph.D., LL.D.
Vice-President and Principal
University of Toronto Scarborough
Professor, Faculty of Kinesiology and Physical Education

I'm all in favor of critical investigation of scientific issues and critical inquiry. I think it's a good idea for the University of Toronto to sponsored a conference where diverse points of view are presented and debated. That's how we learn to distinguish science from pseudoscience and "whose knowledge counts."

There is no possibility that this conference meets those minimal academic requirements.

Here's the welcome message from the Chair of Anthropology and the Associate Chair of Health Studies [see Population Health and Policy Conference].

Welcome to the second Population Health and Policy Conference at UTSC! This event demonstrates not only the energy and initiative of our student organizers, but also the enthusiasm of the students in the Health Studies programs at UTSC. The faculty in Health Studies are very proud of the commitment of our students.

The Health Studies programs promote an understanding of health across a spectrum of academic perspectives: from the clinical and biological health sciences, to social science and humanistic ways of knowing. What binds together these disciplinary approaches is a consciousness of the need for rigorous biological knowledge to be understood in tandem with the social milieu of human health and embodiment.

The programs are built around the bio-medical paradigm, to which the faculty in the program are unreservedly committed. This model has been spectacularly successful in increasing the life span and wellbeing of the majority of people around the world. At the same time Health Studies students learn how to view this paradigm critically through a variety of lenses, notably with respect to such issues as inequality of access, social factors that influence the prevalence of disease and the likelihood of cure, the impacts of government policy on health, and the perspectives of diverse practitioners and clients within the broad health care system. The theme of this year’s conference is Alternative Medicine and the ideas and practices it offers to complement standard health care and the biomedical model, including its emphasis on nutrition and lifestyle. As students and faculty we hold Alternative Health to the same standards of rigorous inquiry and critical appraisal that we apply to other aspects of our society.

The program covers much ground and promises to be stimulating and exciting. We look forward to seeing you there.

Prof. Michael Lambek, Chair, Department of Anthropology

Prof. John Scherk, Associate Chair, Health Studies

Apparently there are at least two ways of knowing the truth; science and the "humanistic way of knowing." I'm disturbed to see that students and faculty are holding alternative health to "the same standards of rigorous inquiry and critical appraisal that we apply to other aspects of our society." It suggests that we're in a lot more trouble than just alternative medicine.

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Here's how an atheist discusses the problem of evil

Sophisticated Christian: My God exists and He is omnipotent, kind, and loving. He chooses to allow evil because X, Y, and Z.

Atheist: If your god exists (he doesn't) and if he is omnipotent, kind, and loving (he isn't) then he MUST create a perfect world where there is no evil. I reject your arguments X, Y, and Z for the following reasons. (Blah, blah, blah.) Because MY version of YOUR imaginary god requires that he create a world where there is no evil, and because there is evil in the world, god doesn't exist.

Discuss.

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Bacterial resistance to antibiotics has nothing to do with evolution according to Michael Egnor MD

Sorry, I couldn't resist. Here's what Michael Egnor says on Evolution News & Views (sic): No, Despite Often-Heard Claims, Antibiotic Resistance in Bacteria Is Not Evolution.

This notion, however, is mistaken. Bacterial resistance to antibiotics has nothing to do with evolution. Evolution, in the Darwinian sense of undirected (unintelligent) process of random heritable variation and natural selection, is the process by which populations of living things change over time without intelligent agency causing or guiding the process. When the process of change in populations is guided by intelligence, it is called artificial selection -- breeding.

Of course I'm not the first to point this out. Charles Darwin, in the Origin of Species, made exactly the same argument. In his first chapter, he discussed artificial selection -- animal husbandry and breeding of plants. In subsequent chapters he developed an argument that in nature, changes in population are accomplished by natural selection, without intelligent agency. Darwin distinguished artificial selection from natural selection -- he distinguished breeding from evolution, and of course his theory of evolution is a theory of natural selection, not a theory of animal husbandry or plant breeding, which had been practiced for thousands of years and to which Darwin contributed nothing.

Bacterial resistance to antibiotics is artificial selection. Antibiotics are intelligently designed by medical researchers, deliberately administered to patients by doctors, who understand that there are some bacteria that are not sensitive to the antibiotic and that have the potential to proliferate. Actually, the administration of antibiotics that kill some but not all of the bacteria in the patient is quite deliberate, because there are huge populations of beneficial bacteria (e.g. in the gut) that should not be killed since they are necessary for health.

Shhhh. Don't tell Michael Behe who wrote a whole book based on resistance to antimalarial drugs.

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A quiz on Darwin's Theory of Evolution

Someone named James Lewis at a blog named American Thinker seems to be upset about journalists who question politicians about evolution. He wrote a little quiz for journalists. There are ten questions. He claims that "Any biology student should ace it." Denyse O'Leary liked the questions [Quiz for media on Darwin’s theory of evolution]. She's a journalist but she didn't give us her answers. I can't imagine why.

I think I can give reasonable answers to most of the questions except #3 and #6. Question #10 is hard and so is question #1. I'm not sure if James Lewis would like my answers. What do you think?

1. What is a biological species? How does it differ from a variety? Give examples.
2. How has Darwinian theory changed since Darwin? (Be specific.)
3. Define the two criteria for "Darwinian fitness."
4. What are "Darwin finches?" Where are they found?
5. What is the function of HOX genes?
6. What is meant by "ultra-conservation" in evolution? Give two examples.
7. Give an example of a recent evolutionary change in humans, within the last 10,000 years.
8. What is parallel evolution? Give an example.
9. What is meant by "genetic drift"?
10. Why are there two sexes in most species?

Notice that random genetic drift has recently penetrated the thick sculls of many creationists. That's pretty amazing. I wonder if they can explain it?

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Is the University of Toronto promoting quackery and pseudoscience?

There's a conference this Saturday at the University of Toronto on the Scarborough campus. It features presentations by a number of leading homeopaths and naturopaths. You may not be familiar with them so if you want a brief summary of their quackery check out Scott Gavura's post at Science-Based Medicine: Pseudoscience North: What’s happening to the University of Toronto?.

That post documents a number of very troubling things going on at my university.

The conference is organized by an outside a student group who pays to hold the event on the university campus. This is very common and it does not mean the the university endorses the conference. I believe the contract specifies that such an endorsement must not be implied or stated.

The poster contains a prominent sign using the University of Toronto logo and crest. That certainly looks to me like the university is sponsoring and endorsing the event. I am trying to contact Bruce Kidd, Principal of the University of Toronto, Scarborough to clarify the situation.

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