The latest attempt is by Ann Gauger posting on the best Intelligent Design Creationist website.1 She outlines her case at: Is Evolution True? Laying Out the Logic.
- Evolution is a proven fact. It can be easily observed in the lab.
- The evidence that evolution has occurred in the past is overwhelming. This is especially true of molecular evolution. It would be perverse to ignore all this evidence and claim that genes have not evolved over billions of years.
- Primitive enzymes were probably promiscuous—they were able to catalyze reactions with a large range of related substrates [The Evolution of Enzymes from Promiscuous Precursors]. Many modern enzymes have broad specificity.
- Homologous enzymes with different, but related, specificities probably evolved from promiscuous ancestral enzymes following a gene duplication event and subsequent specialization of the two copies. Evolution in the two lineages occurs by a combination of natural selection and random genetic drift.
- It's possible to deduce the amino acid sequence of an ancient enzyme from a phylogenetic tree. Some ancient enzymes have been constructed and some of them react with multiple related substrates (promiscuous) as predicted.
- Therefore, it's reasonable to conclude that homologous enzymes with different specificities can evolve from promisuous enzymes in this manner.
This begs the question of whether evolution is true. It is a circular argument unsubstantiated by the evidence and unfalsifiable. No one can know what ancient enzymes actually looked like, and whether they really had such broad catalytic specificities.There you have it. This is one of the very best IDiot arguments for the existence of god(s).
In contrast, our argument is as follows:
- Is evolution true? Test case: Do enzymes evolve by a process of natural selection and random mutation?
- Modern enzymes are the only thing we can test.
- No one knows if ancient enzymes were different. They are lost in the deep past, so claims with regard to their promiscuity or ability to evolve are hypothetical and unfalsifiable.
- Modern enzymes can't evolve new functions, based on our own experiments.
- We haven't tested the universe of modern enzymes, so our result is qualified, but the nine most similar enzymes did not change function.
- Our estimate for the likely waiting time for an enzyme to evolve a new function is at least 1015 years.
- Therefore evolution of enzymes is likely to be impossible.
- Given the sophistication of enzymes and the way they work together, intelligent design is the best explanation for the origin and current diversity of modern enzymes.
Are you still wondering why I call them IDiots?
1. There's not a lot of competition.