Saturday, March 24, 2007

Summary of Genes on Human Chromosomes

 
I've prepared a table of the number and types of gene on each human chromosome based on the data at the Ensembl site managed by the Wellcome Trust Sanger Institute in Cambridge UK.

The total number of genes comes to 26,290.

The different categories of gene are:

Known: The "known" protein-encoding genes are those for which there is solid full-length cDNA evidence that they are actually expressed.

Novel: The "novel" class is reserved for genes that are predicted but lack confirming evidence.

miRNA: Micro RNAs are short single-stranded RNAs that are thought to play a role in regulating gene expression.

snRNA: Small nuclear RNAs are required for a number of cellular processes such as RNA processing. Those required for splicing associate with proteins in the nucleus to form small nuclear ribonuleoprotein particles or "snurps."

rRNA: Ribosomal RNA forms the core of the ribosome.

snoRNA: Small nucleolar RNAs are required for proper processing of ribosomal RNA. The are located in the nucleolar region of the nucleus because that's where ribosomal RNA is made.

other RNA: The "other" category includes transfer RNA (tRNA) and some specialized RNAs such as 7SL RNA and P1 RNA.
Chr. Size (kb)Protein
known
Protein
novel
Pseudo-
genes
miRNArRNAsnRNAsnoRNAother
RNA
    Total
    Genes
1
2
3
4
5
6
7
8
9
10
11
12
13
14
15
16
17
18
19
20
21
22
X
Y
247,249,719
242,951,149
199,501,827
191,273,063
180,857,866
170,899,992
158,821,424
146,274,826
140,273,252
135,374,737
134,452,384
132,349,534
114,142,980
106,368,585
100,338,915
88,827,254
78,774,742
76,117,153
63,811,651
62,435,964
46,944,323
49,691,432
154,913,754
57,772,954

2,146
1,375
1,111
828
922
1,103
984
736
921
819
1,390
1,088
358
661
657
915
1,232
293
1,428
612
271
509
878
86
54
84
47
59
63
29
68
32
38
35
52
51
10
28
65
49
60
20
49
15
23
26
37
27

159
40
45
32
23
81
48
19
66
52
61
38
41
25
34
25
56
8
45
29
9
39
80
2

43
23
24
21
19
17
31
17
26
16
19
21
14
51
15
14
32
5
71
16
7
15
58
6

42
24
21
13
22
16
14
14
11
17
19
15
9
14
6
13
10
42
6
8
10
2
19
6

178
116
89
81
74
82
64
61
43
64
51
77
29
42
43
39
47
12
14
32
5
18
64
14

60
37
30
16
18
25
27
21
15
8
40
21
12
56
95
14
29
12
12
16
5
11
25
3

93
74
66
58
67
56
62
39
47
42
47
65
34
38
35
31
52
21
18
34
6
20
48
2

2,616
1,733
1,388
1,076
1,185
1,328
1,250
920
1,101
1,001
1,618
1,338
466
890
916
1,075
1,462
401
1,598
733
325
601
1,129
140

3 comments :

  1. Great concise table. It looks as if the columns for protein known and total genes need tidying up.

    ReplyDelete
  2. In what sense do they need tidying up? Does the table look bad in some browsers? It's a real pain to make tables like this on blogger but there's no easier way to do it.

    ReplyDelete
  3. I hesitated in mentioning the apparent problem because of the possibility that it was a browser related issue but does seem more likely that it is a blogger problem. I still use MS Internet Explorer 6.0. In the total genes column for chromosome 1 the entry is 2,61 the final 6 of the actual figure of 2,616 appears as the entry for chromosome 2. This pattern continues so that the column for total genes (and proteins known) extends to twice the length of the table. As no one else seems to be having a problem with viewing the table it remains a possibility that the problem is specific to my computers configuration. Thank you for replying to my previous comment so quickly.

    ReplyDelete