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Monday, January 23, 2012

Monday's Molecule #156

 
This is one of the most important molecules on Earth. Without it we wouldn't be around and neither would most species. The revised structure is shown here. The one shown in the textbooks is wrong and this includes my own recently published edition of Principles of Biochemistry. Oops!

You need to identify the molecule, including the part with the white carbon atoms. You also need to specify how this molecule differs from the one shown in most textbooks.

Post your answer in the comments. I'll hold off releasing any comments for 24 hours. The first one with the correct answer wins. I will only post correct answers to avoid embarrassment.

There could be two winners. If the first correct answer isn't from an undergraduate student then I'll select a second winner from those undergraduates who post the correct answer. You will need to identify yourself as an undergraduate in order to win. (Put "undergraduate" at the bottom of your comment.)

Some past winners are from distant lands so their chances of taking up my offer of a free lunch are slim. (That's why I can afford to do this!)

In order to win you must post your correct name. Anonymous and pseudoanonymous commenters can't win the free lunch.

Winners will have to contact me by email to arrange a lunch date.

UPDATE: The molecule is the iron-sulfur-molydenum cluster with bound homocitrate. The central atom was thought to be nitrogen but recent work has shown that it is most likely carbon. The cluster is in the active site of bacterial nitrogenase, an enzyme responsible for fixing atmospheric nitrogen and converting it to ammonia. This is a key part of the nitrogen cycle. The winner is David J. Schuller. I don't know if he will come for lunch.

Winners
Nov. 2009: Jason Oakley, Alex Ling
Oct. 17: Bill Chaney, Roger Fan
Oct. 24: DK
Oct. 31: Joseph C. Somody
Nov. 7: Jason Oakley
Nov. 15: Thomas Ferraro, Vipulan Vigneswaran
Nov. 21: Vipulan Vigneswaran (honorary mention to Raul A. Félix de Sousa)
Nov. 28: Philip Rodger
Dec. 5: 凌嘉誠 (Alex Ling)
Dec. 12: Bill Chaney
Dec. 19: Joseph C. Somody
Jan. 9: Dima Klenchin

Sunday, January 22, 2012

The Modern Molecular Clock

The first molecular phylogenetic trees were constructed from the amino acid sequences of small proteins. One of those proteins was cytochrome c and it turned out to be very useful because homologues could be found in all species, including bacteria.

The original trees were published by Emanual Margoliash but I'm showing a later version here from Fitch and Margoliash (1967). This is a very famous tree that's found in many textbooks. (The version shown here is from Mulligan (2008).)

From the very beginning, the authors of these molecular phylogenetic trees noted that the rate of change in each lineage was approximately constant. You can see that in the tree shown here. The number of changes in the lineage leading to yeast (Saccharomyces) is 17+10+2=31 from the common root. The number of changes in the lineage leading to insects is 31 or 28, depending on the species. The number leading to humans and monkeys is 32.

Margoliash on "Homology" (1969)

Emanuel Margoliash (1920 - 2008) is famous for his studies of the evolution of cytochrome c genes/proteins. His lab sequenced dozens of them and he published some of the first molecular phylogenetic tress back in the early 1960s.

I recently stumbled on a letter he published in Science back in 1969 (Margoliash, 1969). It's about how you define "homology." This is one of my pet peeves. I've been trying to teach people for years that homology refers to the fact that two genes share a common ancestor. It a conclusion based on evidence such as sequence similarity. For example, if two genes/proteins are more than 30% identical over their entire length then you can conclude that they are homologous—they descend from a common ancestor. The conclusion is based on evidence, such as 30% sequence identity. Don't confuse "similarity" and "homology" because they are two different things.1

Homology is like being pregnant. Either you are or you aren't. You can't be 30% pregnant and you can't be 30% homologous.

I knew that the definition of homology had changed over the years but I didn't know that the dispute over its usage in molecular phylogeny started in the 1960s. Here's the Margoliash letter.
I regret the error in citation (the journal name was given as Nature, rather than Science), which crept in among the 462 references of the review (1) to which Winter, Walsh, and Neurath take exception (Letters, 27 Dec.). In that review, the term homologous was taken to imply, in parallel to universal biological usage, "that the genes coding for the polypeptide chains considered, in all the species carrying these proteins, had at one time a common ancestral gene," and we stated that when this concept is not intended "it would be best to use any of the numerous synonyms of 'similar' and 'similarity' and not appear to be prejudging the issue of evolutionary relations." The "pointed and specific criticism" followed, and was entirely contained in the sentence: "Other definitions may cause confusion and are unlikely to supplant well established biological usages." The "other definitions" referred to the article by Neurath, Walsh, and Winter (2), in which they state, "The term homology as applied to proteins refers to similarity in amino acid sequence," and later, that comparisons of protein structures "must be interpreted on a statistical basis lest we misinterpret random similarities."

On this last score there is no argument. Winter, Walsh, and Neurath will surely agree that in this field erroneous conclusions are likely to arise from the lack of an appropriate statistical distinction between random similarities and similarities of structure greater than can result from random phenomena. An excellent method of performing just such a distinction was published by Fitch (3), and although Neurath, Walsh, and Winter acknowledge it in their article (2), they do not use any acceptable statistical techniques in their comparisons of proteases. Thus, even by their own definition they fail to show "homology."

Homology, in any biological evolutionary context has a generally understood and well-defined meaning, namely the one we have adopted for use in protein primary structure comparisons. One cannot argue that such comparisons represent an area of knowledge separate from evolutionary biology, and that therefore one may use the same words for other meanings, since such protein studies obtain their interest largely in terms of evolutionary concepts and have their major impact in the taxonomic-evolutionary field. Winter, Walsh, and Neurath justify their novel definition of "homology" by maintaining that, without fossil remains, it is not possible to decide whether the structural genes corresponding to a set of present-day proteins are or are not ancestrally related. Apart from the inherent danger of assuming that a problem is insoluble, it may be pointed out that six pages after the definition of "homology," the paper (1) reviewed a statistical method for demonstrating just such ancestral homology. One requires enough primary structures to derive a "statistical phylogenetic tree," as has been possible in the case of cytochrome c (4). From such a tree a simple statistical calculation permits one to approximate the number of residues in a set of proteins that will remain invariant, because of biological necessity, no matter how many species are examined (5). If, in the comparison of any two proteins of this set, the number of identical residues is substantially in excess of the number that remain invariant in the entire set of proteins, then clearly this excess cannot result from functional convergence from different phylogenetic origins, a process yielding analogous structures, and, therefore, it can only be attributed to ancestral homology. In such a procedure, the assumption of the constancy of the genetic code has replaced the fossils of the morphological evolutionist.

Even if one does not accept the validity of such a demonstration, it is difficult to understand why there is an insistence on using the word "homology" for "similarities of protein primary structure greater than random." Any of the over 30 synonyms of "similarity" (6) or a variety of elegant neologisms would do, and prevent an insidious misunderstanding likely to arise in biological literature. Rather than take Alice in her confused trip in Wonderland as a model for logical scientific nomenclature, I prefer to follow the 17th-century poet reacting against a form of debasement of the language then prevalent, and "call a cat a cat" (7).

E. MARGOLIASH
Department of Molecular Biology,
Abbott Laboratories,
North Chicago, Illinois 60064
References

1. C. Nolan and E. Margoliash, Ann. Rev. Biochem. 37, 727 (1968).
2. H. Neurath, K. A. Walsh, W. P. Winter, Science 158, 1638 (1967).
3. W. M. Fitch, J. Mol. Biol. 16, 9 (1966).
4. W. M. Fitch and E. Margoliash, Science 155, 279 (1967).
5. W. M. Fitch and E. Margoliash, Biochem. Genet. 1, 65 (1967).
6. Roget's Thesaurus (St. Martin's Press, New York, 1965).
7. N. Boileau, Satires 1, line 52 (1660). "J'appelle un chat un chat, et Rolet un fripon."


1. Very few people pay attention to me. I appear to be fighting for a lost cause.

Margoliash, E. (1969) Homology: A Definition. Science 163:127

Friday, January 20, 2012

Understanding Mutation Rates and Evolution

The recent article by physician Joseph A. Kuhn contains a lot of errors and misunderstandings [Physicians Can Be IDiots]. Today I want to focus on one paragraph.
The complexity of creating two sequential or simultaneous mutations that would confer improved survival has been studied in the malaria parasite when exposed to chloroquine. The actual incidence of two base-pair mutations leading to two changed amino acids leading to resistance has been shown to be 1 in 1020 cases (42). To better understand this incidence, the likelihood that Homo sapiens would achieve any single mutation of the kind required for malaria to become resistant to chloroquine (a simple shift of two amino acids) would be 100 million times 10 million years (many times the age of the universe). This example has been used to further explain the difficulty in managing more than one mutation to achieve benefit.
The reference is to The Edge of Evolution by Michael Behe. His book was published in 2007 but I never got around to reviewing it thoroughly—partly because it's so difficult to explain where he goes wrong.1 Here's my take on one part of the book: The Two Binding Sites Rule. This post covers "chloroquine-complexity clusters" (CCC).

Thursday, January 19, 2012

Congratulations Vip!

 
Here's Vipulan Vigneswaran with his fabulous Biochemistry textbook that he won by contributing to Monday's Molecule [And the Winner Is ...]. Vip is studying Chemistry at the University of Toronto.


Alain de Botton Tells Us the Good Things About Religion

 
Here's a TED talk by Alain de Botton. He claims to be an atheist but he's promoting Atheism 2.0. That's a version of atheism that incorporates all the good parts of religion like how they can brainwash children and con people out of lots of money. And pilgrimage. Let's not forget the value of pilgrimage and the importance of travel. (Think Canterbury Tales!)

There's a certain mysticism about TED talks that I deplore. In order to be a successful TED talker you need to be articulate and clever. You need to be engaging and just a little bit radical—though not too radical. That's just about all it takes to get an enthusiastic standing ovation from the people who comes to listen to these 18 talks. What you're actually saying doesn't really count for anything as this example plainly shows.

The mantra of TED talks is "Ideas Worth Spreading" but if you think about it there aren't very many important new ideas that can be explained in 18 minutes. On the other hand, if you want to spread ideas that your audience already agrees with then TED talks are just the thing for you.




[Hat Tip: PZ Myers: Alain de Botton is right about one thing.]

James Shapiro Publishes on Evolution News & Views

James A. Shapiro, author of Evolution: a View from the 21st Century has been criticized for being an Intelligent Design Creationist, or at least a sympathizer. He denies it but his denials sound very much like someone who protests too much.

Shapiro has now been allowed to post an article on the main IDiot blog, Evolution News & Views [A Response to Ann Gauger's and Douglas Axe's Comments. I don't agree with his response but that's not the point. Do you know any respectable evolution supporter who would post on a creationist blog?

Can you imagine his University of Chicago Colleague, Jerry Coyne, posting an article on the flagship blog of the Discovery Institute?


Physicians Can Be IDiots

 
Joseph A. Kuhn is a physician at the Baylor University Medical Center at Dallas. This is a Christian medical center associated with Baylor University in Waco, Texas. Joseph Kuhn published an article in a recent issue of Baylor University Medical Center Proceedings: Dissectring Darwinism.

Kuhn has an M.D. degree. He is not a scientist and he has no obvious expertise in biology and/or evolution. He is a Roman Catholic. He is definitely an Intelligent Design Creationist.

Let's look as what this IDiot has to say ...
The primary conflicts or anomalies with neo-Darwinian evolution lie in the failure of mutation and natural selection to account for the formation of DNA, the information of DNA, or the complexity of the human cell. In all fairness, many physicians, medical students, and college students have not been shown the weakness of Darwinian evolution. They haven’t been shown the failure of the Miller-Urey experiments to explain DNA, RNA, or protein formation; the paucity of fossil data; or the refutations of transitional species based on a growing biochemical understanding of complex systems and the limits of DNA mutation to account for the formation of new DNA, new chromosomes, and therefore new species.

In contrast, how is it possible that the majority of National Academy of Science members (who should know the above weaknesses) fully believe that random mutation and natural selection can explain the origin of DNA and the subsequent generation of a vast array of protein systems within complex cells? It is possible that the biologist, the paleontologist, and the anthropologist are each studying a small portion of the picture and do not have the education and training to see the full picture. More likely, their previous research relies on the established paradigm of Darwinian evolution to provide structure for their work. As the limitations of existing paradigms become apparent, adoption of a new paradigm typically requires at least a full generation, since existing practitioners and scientists often hold on to the old paradigm.
There's so much wrong here that I hardly know where to begin. First, biological evolution, whether it be the outmoded neo-Darwinian model or a more modern version, was never intended to explain the origin of life. We don't know how life originated but that has nothing to do with the truth and power of evolution as an explanatory mechanism.

Second, members of the National Academy of Science—and all other scientists in the USA and many other countries—are not stupid. The idea that they would all fail to see the truth about evolution because they "do not have the education and training to see the full picture" is silly beyond belief. The idea that they might be blind to the truth because they adhere to an incorrect Darwinian paradigm is ridiculous. The idea that a physician at a Christian university might be in a better position to recognize the truth about evolution is something that only a true IDiot could believe.

The standard IDiot talking point these days is that students and the general public are being misled because scientists won't teach all the problems and controversies concerning biological evolution. This is an attitude that completely ignores all the debate and discussion that has been taking place on the internet and in popular books, magazines, and journals over the past four decades. None of the problems and controversies have stood up to close analysis in spite of the fact they have been dogmatically defended by dozens of leading IDiots.

Of course Joseph Kuhn, the physician, knows nothing about this. That's why he writes ...
When the Texas State Board of Education voted to recognize the weaknesses of Darwinian evolution in explaining the origin of the species, it was a result of 3 full days of intense debate and scientific dispute. In 2011, when new textbooks were presented to the State Board of Education, 9 out of 10 failed to provide the mandated supplementary curricula, which would include both positive and negative aspects of evolution (44). Moreover, several of the textbooks continued to incorrectly promote the debunked Miller-Urey origin of life experiment, the long-discredited claims about nonfunctional appendix and tonsils, and the fraudulent embryo drawings from Ernst Haeckel. In essence, current biology students, aspiring medical students, and future scientists are not being taught the whole story. Rather, evidence suggests that they continue to receive incorrect and incomplete material that exaggerates the effect of random mutation and natural selection to account for DNA, the cell, or the transition from species to species.

The Texas State Board of Education guidelines do not propose teaching any other alternatives to Darwinian evolution. Rather, the students of tomorrow and teachers of today should appropriately recognize that there are weaknesses that have been pointed out by reasonable scientists. In this dissection of Darwinism, we have cut into the weaknesses of the fossil evidence for human evolution, the failure of the fossil data to demonstrate substantial transition species, and the awareness of the sudden formation of most species in a short window of time, with no significant subsequent variation. More importantly, this physician-perspective article emphasizes the extreme impossibility of the natural formation or self-formation of billions of nucleotides in a specific sequence, allowing for the coding of RNA and proteins in a complex cell with thousands of interrelated and irreducibly complex functions. The article also enlightens the reader regarding the conflicts and difficulty of using natural selection and mutation to explain the simultaneous or sequential changes in cellular DNA, involving entirely new strands of DNA and thousands of new proteins, which are necessary for the formation of new species.
It's hard to imagine what must be going on inside the head of someone who could write such drivel. Let's say that the Texas Board of Education succeeds in brainwashing students about the "weaknesses" of evolution. Is that going to change the minds of any expert who studies biological evolution for a living? Is that going to lead to a new generation of scientists who accept Intelligent Design Creationism? No, not even in Texas.

Only an IDiot could believe that forcing Intelligent Design Creationism down the throats of students in some parts of southern USA will eventually lead to a "paradigm shift" in thinking about evolution. Only an IDiot physician could believe that he knows more about evolution than the experts. In fairness, you've got to give the creationists some credit for convincing some, otherwise intelligent, people that 99.9% of all scientists are really, really stupid.

UPDATE:Jonathan Wells defends Joseph A. Kuhn, MD ["Shut up," Coyne Explained].


[Hat Tip: Jerry Coyne in Creationist paper in a medical journal.]

Canadian Blog Awards: Science and Technology

 
Voting for The Canadian Blog Awards ends tomorrow so this is your last chance to pick the best of the best(?).

Most of you will be interested in the science blogs. The category is Best Science and Technology Blog. Here are the finalists ...

Sync.ca
Here at Sync, we strive to bring you the latest in news, reviews and opinions from the tech universe. It′s our way of helping to keep Canadians in sync with tech and gadgets that surround us in our daily lives. Never miss a beat: stay in Sync.
iPhoneinCanada.ca
iPhoneinCanada.ca was started in late 2007 in Vancouver, BC. The site was created to document using the first generation iPhone in Canada. The blog has evolved along with the iPhone and we are now the leading Canadian iPhone authority for news, reviews, tips, tricks and anything else iPhone-related. We are powered by a fantastic iPhone community.
Jon Arnold's Analyst 2.0 Blog
Independent analysis of the IP communications sector - VoIP, Mobile Broadband, IPTV, Unified Communications, Telepresence, Mashups, Web 2.0, Social Media, etc. Plus, my thoughts on all the other things I enjoy during the rest of the day like the Red Sox and great music. And more recently, Smart Grid too!
Hi-Sci-Fi
Creator, producer, writer and host of HiSciFi is Irma Arkus. Over the years, she noticed that the idea of sitting by herself in a studio is unappealing, and potentially dangerously unfunny too. So, Irma had quite a few lovely co-hosts over the years: Andrew Yang, Jevon Ryan, Gregory Milne, and Tarek Suliman. Irma is evidently a man-eater.

BROADCASTING OF HISCIFI

HiSciFi is taped and broadcast live, every Friday at 5:00-6:00 p.m. on CJSF 90.1FM in Burnaby, British Columbia, Canada. Currently, HiSciFi is evaluated for syndication.

www.HiSciFi.com is the place where the show gets a second life as a podcast, and as such can be found at numerous podcast distribution sites, as well as distributed by Mininova.org, PirateBay.com and BTJunkie.org via bit-torrent.
Mark Evens Tech
My company, ME Consulting, creates digital strategies and does tactical execution for startups and entrepreneurs that want to take their marketing efforts to the next level. Having worked for startups, covered them a reporter and consulted with them for the past three years, I understand their goals, and what they need to be successful.
Hmmm ....

There seems to be a slight problem. There are no "science" blogs in the running for best science and technology blog! This is one of my pet peeves. Why can't people understand the difference between science and technology?

When's the last time you saw an actual science project win a Science Fair?

If you really want to cast a vote then go to Best Religion and Philosophy Blog and vote for Canadian Athiest.


Wednesday, January 18, 2012

False Dichotomy

 
A false dichotomy is when you are presented with two choices and told that if one is wrong then the other must be correct but there are actually other choices.

Intelligent Design Creationists are very fond of this argument. They tell you that there are only two choices when it comes to explaining biology: either Darwinism or Intelligent Design Creationism. If a given feature of the biological world cannot possibly be explained by Darwinism, then God must exist and he must have designed the feature.

Here's Douglas Axe illustrating the false dichotomy on Evolution News & views [Let Science Be the Arbiter: A Reply to James Shapiro].
As an ID proponent, I've put forward the scientific case for thinking that the thousands of distinct structures that enable protein molecules to perform their specific tasks inside cells cannot have arisen in a Darwinian way. Moreover, the facts of this problem seem to preclude any naturalistic solution, Darwinian or not.

There is no crutch here. The aspects of protein structure that appear to preclude a naturalistic origin have been described in detail. If Shapiro or anyone else were to show in detail how these are overcome by a naturalistic mechanism, then my argument would fall and I would let it fall. But the reverse needs to be true as well. Scientists who personally side with naturalism have to be willing to let naturalism fall, as otherwise they would be guilty of using a crutch to prop it up.
This is actually an attempt to get around the charge of false dichotomy by extrapolating from a rejection of Darwinian explanations to any naturalistic explanation. If Axe is truly able to demonstrate that his "data" cannot possibly be explained by any naturalistic means then it follows logically that the only other type of explanation has to be supernatural. But what Axe is really arguing against is a Darwinian explanation and it's only his lack of imagination and arrogance that allows him to claim that no other naturalistic explanation is possible.

As we have seen time after time, the Intelligent Design Creationists do not have a scientific theory or any kind of scientific explanation for biological phenomena. All they have is criticisms of science—criticisms that are usually based on a lack of knowledge. When will we see an ID explanation of protein folding and function?


The 2012 Edge Question

 
John Brockman is, among other things, a literary agent with a large stable of famous scientists. He runs a website called The Edge and every year he asks a question and solicits responses from his clients and admirers. This year's question is WHAT IS YOUR FAVORITE DEEP, ELEGANT, OR BEAUTIFUL EXPLANATION?
Scientists' greatest pleasure comes from theories that derive the solution to some deep puzzle from a small set of simple principles in a surprising way. These explanations are called "beautiful" or "elegant". Historical examples are Kepler's explanation of complex planetary motions as simple ellipses, Bohr's explanation of the periodic table of the elements in terms of electron shells, and Watson and Crick's double helix. Einstein famously said that he did not need experimental confirmation of his general theory of relativity because it "was so beautiful it had to be true."

WHAT IS YOUR FAVORITE DEEP, ELEGANT, OR BEAUTIFUL EXPLANATION?

Since this question is about explanation, answers may embrace scientific thinking in the broadest sense: as the most reliable way of gaining knowledge about anything, including other fields of inquiry such as philosophy, mathematics, economics, history, political theory, literary theory, or the human spirit. The only requirement is that some simple and non-obvious idea explain some diverse and complicated set of phenomena.

Here are some of my favorites ....

My Favorite Annoying Elegant Explanation: Quantum Theory by Raphael Bousso
Life Is a Digital Code by Matt Ridley
Plate Tectonics Elegantly Validates Continental Drift by Paul Saffo
Watson and Crick Explain How DNA Carries Genetic Information by Gary Klein
Atomism: Reconciling Change with No-Change by Marcelo Gleiser
The 19th Century Explanation of the Remarkable Connection Between Electricity And Magnetism by Lawrence M. Krauss
We Are Stardust by Kevin Kelly
The Principle of Empiricism, or See For Yourself by Michael Shermer

Here are some of my not-so-favorites ....

Fitness Landscapes by Stewart Brand
Sexual Conflict Theory by David M. Buss
Pascal's Wager Tim O'Reilly
Epigenetics by Helen Fisher
Evolutionarily Stable Strategies by S. Abbas Raza
The Destructive Wrath of the General Purpose Computer by Jordan Pollack
Subverting Biology by Patrick Bateson
Sex At Your Fingertips by Simon Baron-Cohen
The Epidemic of Obesity, Diabetes and "Metabolic Syndrome:" Cell Energy Adaptations in a Toxic World? by Beatrice Golomb
Why We Feel Pressed for Time by Elizabeth Dunn
Why Some Sea Turtles Migrate by Daniel C. Dennett
Evolutionary Genetics Explains The Conflicts of Human Social Life by Steven Pinker
The Faurie-Raymond Hypothesis by Jonathan Gottschall
The Gaia Hypothesis by Scott Sampson
The Elegant Robert Zajonc by Richard Nisbett



Scientists vs. Science Writers

 
Follow the discussion on Ed Yong's blog Not Exactly Rocket Science [Every scientists-versus-journalists debate ever, in one diagram].



The main problem isn't represented on the diagram. It's when good/bad journalists write articles in praise of bad science.

Monday, January 16, 2012

What Does a Secular Society Look Like?

 
Casey Luskin wonders What Would the World Look Like if the New Atheists Won the Day?. He's just read Penn Jillette's new book, God, No!: Signs You May Already Be an Atheist and Other Magical Tales, and he's "discovered" by selective quote mining that Penn would persecute Christians if the atheists ever gained power in America.

This leads Casey to speculate on what the secular world would look like if people abandoned their religion. He imagines that it won't be a nice place.
Back to the Secular Decade. If there's one thing to admire about Penn Jillette, it's that he's transparent about what he really thinks. If only more "new atheists" were so transparent, then the public might get a more realistic picture of what Faircloth's "Secular Decade" would really look like.
If Casey had been paying attention, he wouldn't have to look very far. Many European countries are well on their way to being truly secular societies. In the Netherlands, for example, only 34% of the population believes in God [Demographics of atheism]. If the New Atheists were to succeed in America then most people would abandon religion and life would go on pretty much as usual except that the society would become more rational, more understanding, and more tolerant. Creationism would become a joke, gays could marry, and women would have the right to choose. That's what's happened in the Netherlands and many other civilized countries.


Photo Credit: Amsterdam Tourism & Convention Board

The Mind of James Shapiro

I recently read Evolution: a View from the 21st Century by James Shapiro. It was a very annoying and frustrating experience. I do not recommend this book. I've already posted a rebuttal of his silly claim that the Central Dogma of Molecular Biology needs to be revised [Revisiting the Central Dogma in the 21st Century ]

The really frustrating part was trying to figure out Shapiro's agenda. He clearly has one. Is it just that he's against "conventional evolutionary theory"—whatever that is? Or, is he laying the groundwork for introducing God and intelligent design?

Shapiro denies that he's a supporter of intelligent design yet he published several papers with Richard Sternberg, one of the darlings of Intelligent Design Creationism. Furthermore, he (Shapiro) uses many of the same anti-evolution arguments used by Intelligent Design Creationists.

This prompted Bill Dembski to accuse James Shapiro of "dancing in the DMZ between Darwin and design" [Is James Shapiro a Design Theorist?].
For proponents of intelligent design, James Shapiro's constant dancing in the DMZ between Darwin and design can be frustrating. On the one hand, Shapiro is as dismissive of Darwinism as any ID proponent. On the other, he constantly gives public notice that he is not on the side of ID. And yet, methinks he protests too much.
This got a response from Shapiro that has now been posted on Evolution News & Views ["Is James Shapiro a Design Theorist?": James Shapiro Replies]. Here's what Shapiro says ...

What is wrong with "dancing in the DMZ" between intelligent design (as articulated by Michael Behe and others) and neo-Darwinism? Are these two positions the only alternatives? I doubt it. That is why my 1997 article in Boston Review on evolution debates was called "A Third Way." What Dembski calls the "DMZ" (i.e. a zone free of futile conflict) is the place where the real evolutionary science is taking place. I am proud to be there, and I see that an increasing number of people are joining me when they realize that natural genetic engineering, horizontal DNA transfer, interspecific hybridization, genome doubling and symbiogenesis provide solutions to problems recognized to be intractable under the limitations of conventional evolutionary thinking.
Clear as mud. There's one thing I know for sure: horizontal DNA transfer etc. are perfectly compatible with today's evolutionary thinking. If Shapiro is wrong about this—and he is— then maybe he's also misleading us about his belief in intelligent design creationism.

Saturday, January 14, 2012

Phytoplankton Blooms

 
This is a spectacular view of a phytoplanton bloom in the South Atlantic. It was taken by the Envisat satellite on Dec. 2, 2011 [A Southern Summer Bloom].

These phytoplankton blooms usually consist of a single species of microorganism. The fact that they can be seen from space gives you an idea of just how abundant they are. The blooms in the oceans can be due to diatoms or algae but by far the most common large blooms are due to cyanobacteria.

Prochlorococcus sp. and Synechococcus sp. have the largest population sizes of any species on the planet. About 30% of all oxygen production on the planet is due to marine phytoplankton and these two species account for a significant proportion.

A third genus of cyanobacteria, Trichodesmium, is mostly found off the coast of Australia. In addition to producing oxygen by photosynthesis, it is responsible for a considerable proportion of nitrogen fixation in the oceans.


[Hat Tip: Bad Astronomy]