
The latest version of the Tangled Bank has been posted on Behaviorial Eology Blog [Tangled Bank #88].
My latest visit among you, however, was entirely involuntary and maximally stressful. I live in lower Manhattan, just one mile from the burial ground of the Twin Towers. As they fell victim to evil and insanity on Tuesday, September 11, during the morning after my 60th birthday, my wife and I, en route from Milan to New York, flew over the Titanic’s resting place and then followed the route of her recovered dead to Halifax. We sat on the tarmac for 8 hours, and eventually proceeded to the cots of Dartmouth’s sports complex, then upgraded to the adjacent Holiday Inn. On Friday, at 3 o’clock in the morning, Alitalia brought us back to the airport, only to inform us that their plane would return to Milan. We rented one of the last two cars available and drove, with an intense mixture of grief and relief, back home.
.......
I know that the people of Halifax have, by long tradition and practice, shown heroism and self-sacrifice at moments of disaster -- occasional situations that all people of seafaring ancestry must face. I know that you received and buried the drowned victims of the Titanic in 1912, lost one in ten of your own people in the Halifax Explosion of 1917, and gathered in the remains of the recent Swissair disaster.
But, in a sense that may seem paradoxical at first, you outdid yourselves this time because you responded immediately, unanimously, unstintingly, and with all conceivable goodness, when no real danger, but merely fear and substantial inconvenience, dogged your refugees for a few days. Our lives did not depend upon you, but you gave us everything nonetheless. We, 9000 strong, are forever in your debt, and all humanity glows in the light of your unselfish goodness.
And so my wife and I drove back home, past the Magnetic Hill of Moncton (now a theme park in this different age), past the reversing rapids of Saint John, visible from the highway, through the border crossing at Calais (yes, I know, as in Alice, not as in ballet), and down to a cloud of dust and smoke enveloping a mountain of rubble, once a building and now a tomb for 5000 people. But you have given me hope that the ties of our common humanity will bind even these wounds. And so Canada, although you are not my home or native land, we will always share this bond of your unstinting hospitality to people who descended upon you as frightened strangers from the skies, and received nothing but solace and solidarity in your embrace of goodness. So Canada, because we beat as one heart, from Evangeline in Louisiana to the intrepid Mr. Sukanen of Moose Jaw, I will stand on guard for thee.
CANBERRA (Reuters) - Prime Minister Stephen Harper, under fire at home for a troop commitment to Afghanistan that has cost 70 lives, said on Tuesday he would not abandon the country.9-11 showed no such thing. Don't you remember? They didn't attack America because they were poor, miserable, and stupid, they attacked because they hate freedom and democracy. If we stay in Afghanistan and force them to be free and democratic then they'll hate us even more,
"This cause is global and necessary," Harper said in a speech to Australia's parliament on the anniversary of the September 11, 2001, attacks on the United States.
"Because as 9-11 showed, if we abandon our fellow human beings to lives of poverty, brutality and ignorance, in today's global village, their misery will eventually and inevitably become our own," said Harper.
[Photo Credit: REUTERS/Tim Wimborne]
Like most reactions in vivo, the actual Gibbs free energy change for this reaction is zero. Normally you might expect that such a large negative standard Gibbs free energy change would indicate that the forward reaction is coupled to the synthesis of ATP. Indeed, the hydrolysis of the similar thioester bond in succinyl CoA (Step 5 of the citric acid cycle) is coupled to the synthesis of GTP (or ATP). However, in the case of the citrate synthase reaction, the available energy is used for a different purpose. What is this purpose?
The sequence of the coding region of an E. coli ribosomal protein mRNA consists of 21% G's and 23% C's. What do you predict would be the composition of the part of the gene (double-stranded DNA) from which this mRNA coding region is derived?
a) 56% T's
b) 44% T's
c) 28% T's
d) 23% T's
e) impossible to answer correctly
COLUMBUS, Ohio – Research here shows that an obscure form of RNA, part of the protein-making machinery in all cells, might play an important role in human cancer.This is quite ridiculous. I don't know of any researcher who would declare that ultraconserved sequences are junk. This just seems like a distortion of the paper in order to frame the work in a way that's more appealing to the public. The idea is to make it look like this paper overturns the current dogma about junk DNA.
These ultraconserved non-coding RNAs (UCRs) have been considered “junk” by some researchers, but a new report in the September issue of the journal Cancer Cell indicates that this may not be the case.
A large portion of transcription products of the noncoding functional genomic regions have significant RNA secondary structures and are components of clusters containing other sequences with functional noncoding significance (Bejerano et al., 2004a). The UCRs represent a small fraction of the human genome that are likely to be functional but not encoding proteins and have been called the “dark matter” of the human genome (Bejerano et al., 2004a). Because of the high degree of conservation, the UCRs may have fundamental functional importance for the ontogeny and phylogeny of mammals and other vertebrates.Oops! The authors themselves admit that these sequences are thought to be functional. There's nothing in the paper about junk DNA and there's certainly nothing about researchers who think these sequences might be junk.
Calin, G.A. et al. (2007) Ultraconserved Regions Encoding ncRNAs Are Altered in Human Leukemias and Carcinomas. Cancer Cell 12:215-229. [Summary][PDF]
If the scientific discovery of a ‘blueprint’ would justify the design inference, then why is it unreasonable to infer that the genetic code was designed?Pull up your chairs and get out the popcorn. This is going to be fun.
[Photo Credit: The photograph is from the official website of the movie Contact]
"The number of prokaryotes [i.e., bacteria + archaea] and the total amount of their cellular carbon on earth are estimated to be 4-6 ×: 1030 cells and 350-550 Pg of C (1 Pg = 1015 g), respectively. Thus the total amount of prokaryotic carbon is 60-100% of the estimated total carbon in plants, and inclusion of prokaryotic carbon in global models will almost double estimates of the amount of carbon stored in living organisms." (Whitman et al. 1998)and
Numerically dominant--there are approximately 1 million bacteria and 10 million viruses in a milliliter of seawater. There are approximately 0.00000000000000000002 sperm whales per milliliter of seawater.The point about learning to love bacteria is that it's crucial to a full understanding of our place in the world of living things. This is going to come up discussions about complexity. We need to understand that our perspective is heavily biased. As Gould (1996) writes,
Our failure to grasp this most evident of biological facts arises in part from the blindness of our arrogance but also, in large measure, as an effect of scale. We are so accustomed to viewing phenomena of our scale—sizes measured in feet and ages in decades—as typical of nature.
Individual bacteria lie beneath our vision and may live no longer than the time I take to eat lunch or my grandfather spent with his evening cigar. But then, who knows? To a bacterium, human bodies might appear as widely dispersed, effectively eternal (or at least geological), massive mountains, fit for all forms of exploitation and fraught with little danger unless a bolus of imported penicillin strikes at some of the nasty brethren.
[Hat Tip: Christopher Taylor at Catalogue of Organisms]
Gould, S.J. (1996) Planet of the Bacteria. Washington Post Horizon 119:(344). An essay adapted from Full House New York: Harmony Books, 1996, pp. 175-192.
… requiring a parolee to attend religion-based treatment programs violates the First Amendment… While we in no way denigrate the fine work of (Alcoholics Anonymous and Narcotics Anonymous), attendance in their programs may not be coerced by the state.The Centre for Inquiry (Toronto) sponsors the Secular Organizations for Sobriety Group of Toronto (SOSGT), a non-religious organization for alcoholics [SOSGT].
SOSGT credits the individual for achieving and
maintaining his or her own sobriety and is ideal for those
uncomfortable with the spiritual content of 12-step programs.
The group is secular and religiously neutral.
5) Creation science is a real scientific theory — if you want to challenge it, please don’t insult us by just offering a fancy and long-winded “nuh-huh”. I find it funny that Wikipedia attempts this too, but I’ve seen this movie before; it’s called the Consensus on Climate Change (and we all know how that one will end!).Where do these IDiots come up with stuff like this? Creation science is not a real scientific theory by any stretch of the imagination. If Matthew is talking about Biblical Creationism then that fairytale has been disproved by science. If he's talking about any other version of "Creation science" than it's either; (a) also disproved, or (b) vacuous.
6) Someone still has to address for me how teaching an alternative view on the origin of species will forever ruin students’ lives and deny them jobs, houses and weekends up at the cottage. They’re not your kids so what do you care what they learn if it doesn’t affect you?Look at it this way Matthew. We have basically two choices in the classroom. We can teach children things that are correct or we can teach them lies. Call me old-fashioned, but I think it's better to teach the truth. It makes for better citizens in the long run.
9) Ala the Flintstones comment, blindly believing in evolution is like believing Star Trek is a documentary about the future. Reality is though that we’re not eliminating all wars, humanity isn’t evolving past its character flaws and evil tendencies and no matter how much some in our society might like it, we’re not going to grow beyond religious faith. Even the television series outlived this optimistic faith in the human will by DS9. Evolution might be wonderful science fiction with things spontaneously mutating everywhere, but we shouldn’t be confusing it with a scientific principle. Maybe we should also be keeping it in it’s proper place too — media class!No comment, other than to point out there's a reason why we call them IDiots.
[Photo Credit: The photograph shows a typical Boston Red Sox fan celebrating something that got them all excited (Red Sox Connection). (I think their team just lost another game against Toronto.)]
[Hat Tip: Canadian Cynic]