Sandwalk

                                    Strolling with a skeptical biochemist

Sunday, April 03, 2022

Karen Miga and the telomere-to-telomere consortium

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Karen Miga deserves a lot of the credit for the complete human genome sequence. Karen Miga is a professor at the University of Califo...
2 comments:

What do we do with two different human genome reference sequences?

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It's going to be extremely difficult, perhaps impossible, to merge the new complete human genome sequence with the current standard refe...

Segmental duplications in the human genome

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The new completed human genome sequence contains some previously unknown large duplicatons (segmental duplications). This is my third...

Epigenetic markers in the last 8% of the human genome sequence

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The newly sequenced part of the human genome contains the same chromatin regions as the rest of the genome and they don't tell us very m...

A complete human genome sequence (2022)

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The first complete human genome sequence has finally been published. This is my first post on the complete telomere-to-telomere sequence...
Friday, April 01, 2022

Illuminating dark matter in human DNA?

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A few months ago, the press office of the University of California at San Diego issued a press release with a provocative title ... Illu...
10 comments:
Wednesday, March 30, 2022

John Mattick's new book

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John Mattick and Paulo Amaral have written a book that promotes their views on the content of the human genome. It will be available next Au...
1 comment:

John Mattick presents his view of genomes

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John Mattick has a new book coming out in August where he defends the notion that most of our genome is full of genes for functonal noncodin...
14 comments:
Saturday, March 26, 2022

Science communication in the modern world

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Science editors asked young scientists to imagine what kind of course they would have created if they could go back to a time before the pa...
11 comments:
Monday, March 14, 2022

Junk DNA

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My book manuscript has been reviewed by some outside experts and they seem to have convinced my editor that my book is worth publishing. I h...
21 comments:
Sunday, February 20, 2022

Jacques Fresco (1928-2021)

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Jacques Fresco died last December. I am kind of a scientific grandson of Jacques Fresco since he mentored my Ph.D. supervisor, Bruce Albert...
1 comment:
Sunday, January 09, 2022

Akiko Iwasaki talks about mucosal immunity

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Akiko Iwasaki is a Professor of Immunology at Yale and a former student in my department (Dept. of Biochemistry, University of Toronto). Sh...
6 comments:
Saturday, January 08, 2022

What is the best COVID-19 vaccine?

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Take any vaccine you can get whenever you can. Moderna is the probably the very best vaccine and Pfizer-BioNTech is a close second. AstraZen...
7 comments:
Friday, January 07, 2022

Ontario (Canada) hospitals are filling up with fully vaccinated patients

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The Omicron wave is surpassing all records for the number of cases in Ontario. The province has given up on testing for most people so the a...
3 comments:
Wednesday, January 05, 2022

The effect of spike protein mutations in the Omicron variant

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The Omicron variant of SARS-CoV-2 contains a large number of novel mutations in the spike protein. How did these mutations occur and what is...
1 comment:
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