Sandwalk

                                    Strolling with a skeptical biochemist

Monday, May 16, 2022

Wikipedia editors want to supress an article on junk DNA

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I've been trying to fix the Wikipedia artilce on Noncoding DNA but it's quite a challenge because the page is controlled by editors...
8 comments:
Sunday, May 15, 2022

Describing non-coding DNA on the NIH (USA) National Human Genome Research Institute website

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Here's a link to a short podcast on non-coding DNA narrated by Shurjo K. Sen, Program Director, Divison of Genome Sciences. This is the...
Saturday, May 14, 2022

Editing the Wikipedia article on non-coding DNA

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I decided to edit the Wikipedia article on non-coding DNA by adding new sections on "Noncoding genes," "Promoters and regula...
21 comments:
Friday, April 15, 2022

Most lncRNAs are junk

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A hard-hitting review will be published in Annual Review of Genomics and Human Genetics . It shows that the case for large numbers of functi...
4 comments:
Friday, April 08, 2022

The structures of centromeres

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The new complete human genome sequence gives us a first-time look at the structures of human centromeres. This is my sixth post on the c...
2 comments:
Wednesday, April 06, 2022

Genetic variation and the complete human genome sequence

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The new complete human genome sequence adds an extra 8% of DNA sequence that's a source of variation in the human population. The sequen...
Tuesday, April 05, 2022

Two different views of the history of molecular biology

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How can different molecular biologists have such opposite views of the history of their field? I'm posting links to two papers wit...
22 comments:

Transcription activity in repeat regions of the human genome

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A detailed examination of the new complete human genome reveals that 54% of it consists of various repetitive elements. Some of them are tra...
1 comment:
Monday, April 04, 2022

If you were a Harvard freshman you could take a course on the dark matter of the genome.

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Check out this freshperson seminar course on Parts Unknown: The Dark Matter of the Genome at Harvard. It is offfered by Amanda J. Whipple ...
1 comment:
Sunday, April 03, 2022

Karen Miga and the telomere-to-telomere consortium

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Karen Miga deserves a lot of the credit for the complete human genome sequence. Karen Miga is a professor at the University of Califo...
2 comments:

What do we do with two different human genome reference sequences?

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It's going to be extremely difficult, perhaps impossible, to merge the new complete human genome sequence with the current standard refe...

Segmental duplications in the human genome

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The new completed human genome sequence contains some previously unknown large duplicatons (segmental duplications). This is my third...

Epigenetic markers in the last 8% of the human genome sequence

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The newly sequenced part of the human genome contains the same chromatin regions as the rest of the genome and they don't tell us very m...

A complete human genome sequence (2022)

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The first complete human genome sequence has finally been published. This is my first post on the complete telomere-to-telomere sequence...
Friday, April 01, 2022

Illuminating dark matter in human DNA?

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A few months ago, the press office of the University of California at San Diego issued a press release with a provocative title ... Illu...
10 comments:
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