Sandwalk
Strolling with a skeptical biochemist
Friday, April 15, 2022
Most lncRNAs are junk
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A hard-hitting review will be published in Annual Review of Genomics and Human Genetics . It shows that the case for large numbers of functi...
4 comments:
Friday, April 08, 2022
The structures of centromeres
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The new complete human genome sequence gives us a first-time look at the structures of human centromeres. This is my sixth post on the c...
2 comments:
Wednesday, April 06, 2022
Genetic variation and the complete human genome sequence
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The new complete human genome sequence adds an extra 8% of DNA sequence that's a source of variation in the human population. The sequen...
Tuesday, April 05, 2022
Two different views of the history of molecular biology
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How can different molecular biologists have such opposite views of the history of their field? I'm posting links to two papers wit...
22 comments:
Transcription activity in repeat regions of the human genome
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A detailed examination of the new complete human genome reveals that 54% of it consists of various repetitive elements. Some of them are tra...
1 comment:
Monday, April 04, 2022
If you were a Harvard freshman you could take a course on the dark matter of the genome.
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Check out this freshperson seminar course on Parts Unknown: The Dark Matter of the Genome at Harvard. It is offfered by Amanda J. Whipple ...
1 comment:
Sunday, April 03, 2022
Karen Miga and the telomere-to-telomere consortium
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Karen Miga deserves a lot of the credit for the complete human genome sequence. Karen Miga is a professor at the University of Califo...
2 comments:
What do we do with two different human genome reference sequences?
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It's going to be extremely difficult, perhaps impossible, to merge the new complete human genome sequence with the current standard refe...
Segmental duplications in the human genome
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The new completed human genome sequence contains some previously unknown large duplicatons (segmental duplications). This is my third...
Epigenetic markers in the last 8% of the human genome sequence
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The newly sequenced part of the human genome contains the same chromatin regions as the rest of the genome and they don't tell us very m...
A complete human genome sequence (2022)
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The first complete human genome sequence has finally been published. This is my first post on the complete telomere-to-telomere sequence...
Friday, April 01, 2022
Illuminating dark matter in human DNA?
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A few months ago, the press office of the University of California at San Diego issued a press release with a provocative title ... Illu...
10 comments:
Wednesday, March 30, 2022
John Mattick's new book
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John Mattick and Paulo Amaral have written a book that promotes their views on the content of the human genome. It will be available next Au...
1 comment:
John Mattick presents his view of genomes
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John Mattick has a new book coming out in August where he defends the notion that most of our genome is full of genes for functonal noncodin...
14 comments:
Saturday, March 26, 2022
Science communication in the modern world
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Science editors asked young scientists to imagine what kind of course they would have created if they could go back to a time before the pa...
11 comments:
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