Sandwalk

                                    Strolling with a skeptical biochemist

Monday, November 26, 2018

Deflated egos and the G-value paradox

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The Deflated Ego Problem refers to the fact that many scientists were very disappointed to learn we had less than 30,000 genes. Those scient...
51 comments:
Sunday, November 25, 2018

Michael Behe's third book

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I'm looking forward to Michael Behe's third book, which is due to be published in February. As most of you probably know, Michael Be...
23 comments:
Monday, November 19, 2018

Latest Tango in Halifax

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I've known Yana Eglit for many years. She frequently posts comments on this blog but you won't recognize her name because she uses a...
2 comments:
Sunday, November 18, 2018

Revisiting the deflated ego problem

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Humans are just another animal. All animals share a core set of several thousand genes and all mammals have about the same number of homolog...
7 comments:
Friday, November 09, 2018

Celebrating 50 years of Neutral Theory

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The importance of Neutral Theory and Nearly-Neutral Theory cannot be exaggerated. It has radically transformed the way experts think about e...
53 comments:
Thursday, November 08, 2018

DNA Is Not Destiny by Steven J. Heine

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DNA Is Not Destiny: The Remarkable Completely Misunderstood Relationship between You and Your Genes by Steven J. Heine W.W. Norton & C...
11 comments:
Thursday, October 18, 2018

The role of chance in evolution

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I highly recommend this brief editorial by Naruya Saitou: "Chance, Finiteness, and History" (Saitou, 2018). Saitou is a strong pro...
16 comments:
Tuesday, October 16, 2018

John Mattick's latest attack on junk DNA

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John Mattick is the most prominent defender of the idea that the human genome is full of functional sequences. In fact, he is just about the...
19 comments:
Saturday, October 13, 2018

The great junk DNA debate

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I've been talking to philosophers lately about the true state of the junk DNA controversy. I imagine what it would be like to stage a g...
27 comments:
Tuesday, October 09, 2018

Alternative splicing and the gene concept

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I just learned about a workshop scheduled for the end of this month. The topic is: Evolutionary Roles of Transposable Elements and Non-codin...
8 comments:
Monday, August 27, 2018

Who wants "A Sad Case: Owen vs Huxley" pamphlet and a possible Darwin letter?

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A friend has a neighbor who's in possession of a pamphlet from 1863 on the Owen vs Huxley debate. The text of the pamphlet is here: A Re...
13 comments:
Friday, July 13, 2018

How many protein-coding genes in the human genome?

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The three main human databases (GENCODE/Ensembl, RefSeq, UniProtKB) contain a total of 22,210 protein-coding genes but only 19,446 of these ...
16 comments:
Sunday, July 08, 2018

Nature falls (again) for gene hype

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Nature is arguably the most prestigious science journal. Articles published in Nature are widely perceived to be correct, unbiased, and fa...
3 comments:

Disappearing genes: a paper is refuted before it is even published

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Several readers alerted me to a paper that was posted on bioRxiv a few weeks ago (May 28, 2018). The paper claimed that the human genome co...
9 comments:
Wednesday, June 20, 2018

Press release from the Francis Crick Institute misrepresents junk DNA

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Press releases have become a serious problem. I'm frequently upset whenever I read a press release covering a field I'm familiar wit...
25 comments:
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