Sandwalk

                                    Strolling with a skeptical biochemist

Tuesday, October 31, 2017

The history of DNA sequencing

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This year marks the 40th anniversary of DNA sequencing technology (Gilbert and Maxam, 1977; Sanger et al., 1977) 1 The Sanger technique soo...
11 comments:

Escape from X chromosome inactivation

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Mammals have two sex chromosomes: X and Y. Males have one X chromosome and one Y chromosome and females have two X chromosomes. Since female...
1 comment:
Saturday, October 28, 2017

Creationists questioning pseudogenes: the GULO pseudogene

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This is the second post discussing creationist 1 papers on pseudogenes. The first post addressed a paper by Jeffrey Tomkins on the β-globin...
137 comments:
Saturday, October 14, 2017

Creationists questioning pseudogenes: the beta-globin pseudogene

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Jonathan Kane recently (Oct. 6, 2017) posted an article on The Panda's Thumb where he claimed that Young Earth Creationists often don...
67 comments:
Wednesday, October 11, 2017

Historical evolution is determined by chance events

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Modern evolutionary theory is based on the idea that alleles become fixed in a population over time. They can be fixed by natural selection ...
32 comments:
Wednesday, September 13, 2017

Sequencing human diploid genomes

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Most eukaryotes are diploid, including humans. They have two copies of each autosome. Thousands of human genomes have been sequenced but in ...
22 comments:
Monday, September 11, 2017

What's in Your Genome?: Chapter 4: Pervasive Transcription (revised)

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I'm working (slowly) on a book called What's in Your Genome?: 90% of your genome is junk! The first chapter is an introduction to g...
15 comments:
Saturday, September 09, 2017

Cold Spring Harbor tells us about the "dark matter" of the genome (Part I)

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This is a podcast from Cold Spring Harbor [ Dark Matter of the Genome, Pt. 1 (Base Pairs Episode 8) ]. The authors try to convince us that ...
43 comments:
Saturday, September 02, 2017

Winter is coming ... I want this for Xmas (or whenever)

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3 comments:
Wednesday, August 30, 2017

Experts meet to discuss non-coding RNAs - fail to answer the important question

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The human genome is pervasively transcribed. More than 80% of the genome is complementary to transcripts that have been detected in some tis...
4 comments:
Sunday, August 27, 2017

The Extended Evolutionary Synthesis - papers from the Royal Society meeting

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I went to London last November to attend the Royal Society meeting on New trends in evolutionary biology: biological, philosophical and soci...
35 comments:
Friday, August 25, 2017

Niles Eldredge explains punctuated equilibria

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Lots of people misunderstand punctuated equilibria. It's a theory about small changes leading to speciation. In many cases the changes a...
9 comments:

Niles Eldredge explains hierarchy theory

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You may not agree but you should at least know what some evolutionary biologists are thinking.
1 comment:

How much of the human genome is devoted to regulation?

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All available evidence suggests that about 90% of our genome is junk DNA. Many scientists are reluctant to accept this evidence—some of them...
6 comments:
Monday, August 07, 2017

A philosopher defends agnosticism

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Paul Draper is a philosopher at Purdue University (West Lafayette, Indiana, USA). He has just (Aug. 2, 2017) posted an article on Atheism a...
158 comments:
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