Sandwalk

                                    Strolling with a skeptical biochemist

Tuesday, June 27, 2017

Debating alternative splicing (Part IV)

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In Debating alternative splicing (Part III) I discussed a review published in the February 2017 issue of Trends in Biochemical Sciences . T...
26 comments:
Monday, June 26, 2017

Debating alternative splicing (Part III)

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Proponents of massive alternative splicing argue that most human genes produce many different protein isoforms. According to these scientist...
10 comments:
Saturday, June 24, 2017

Debating alternative splicing (part II)

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Mammalian genomes are very large. It looks like 90% of it is junk DNA. These genomes are pervasively transcribed, meaning that almost 90% of...
30 comments:
Friday, June 23, 2017

Debating alternative splicing (part I)

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I recently had a chance to talk science with my old friend and colleague Jack Greenblatt . He has recently teamed up with some of my other c...
30 comments:
Thursday, June 22, 2017

Are most transcription factor binding sites functional?

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The ongoing debate over junk DNA often revolves around data collected by ENCODE and others. The idea that most of our genome is transcribed ...
5 comments:

Jonathan Wells talks about junk DNA

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Watch this video. It dates from this year. Almost everything Wells says is either false or misleading. Why? Is he incapable of learning abou...
22 comments:

Some of my former students

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Some of my former students were able to come to my retirement reception yesterday: Sean Blaine (left), Anna Gagliardi, Marc Perry.
1 comment:

Hot slash buns

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I love hot "cross" buns but now we buy the atheist version.

I retired after 39 years and they gave me an old used book

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... but it was a rather special book ...
18 comments:
Wednesday, June 21, 2017

John Mattick still claims that most lncRNAs are functional

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Most of the human genome is transcribed at some time or another in some tissue or another. The phenomenon is now known as pervasive transcri...
13 comments:
Tuesday, June 20, 2017

On the evolution of duplicated genes: subfunctionalization vs neofunctionalization

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New genes can arise by gene duplication. These events are quite common on an evolutionary time scale. In the current human population, for e...
3 comments:
Monday, June 19, 2017

Austin Hughes and Neutral Theory

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Austin Hughes (1949 - 2015) died a few years ago. He was one of my favorite evolutionary biologists. Chase Nelson has written a nice summa...
15 comments:
Saturday, June 17, 2017

I coulda been an astronomer

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A long time ago I used to belong to the Royal Astronomical Society (amateur astronomers) in Ottawa (Canada). That's me on the right with...
39 comments:
Tuesday, June 06, 2017

June 6, 1944

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Today is anniversary of D-Day—the day British, Canadian, and American troops landed on the beaches of Normandy. 1 For baby boomers it mea...
27 comments:

Stephen Meyer "predicts" there's no junk DNA

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Here's an interview with Stephen Meyer on the Evolution 2.0 website: Stephen Meyer Debates Perry Marshall – Intelligent Design vs. Evol...
37 comments:
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