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In fact, Watson discusses tRNA and rRNA genes in the first edition of his book.  "},"link":[{"rel":"edit","type":"application/atom+xml","href":"https:\/\/www.blogger.com\/feeds\/37148773\/4761741525215825233\/comments\/default\/5227516096814337529"},{"rel":"self","type":"application/atom+xml","href":"https:\/\/www.blogger.com\/feeds\/37148773\/4761741525215825233\/comments\/default\/5227516096814337529"},{"rel":"alternate","type":"text/html","href":"https:\/\/sandwalk.blogspot.com\/2020\/11\/why-is-central-dogma-so-hard-to.html?showComment=1605642414310#c5227516096814337529","title":""},{"rel":"related","type":"application/atom+xml","href":"https:\/\/www.blogger.com\/feeds\/37148773\/4761741525215825233\/comments\/default\/2017101883626346671"}],"author":[{"name":{"$t":"Larry Moran"},"uri":{"$t":"https:\/\/www.blogger.com\/profile\/05756598746605455848"},"email":{"$t":"noreply@blogger.com"},"gd$image":{"rel":"http://schemas.google.com/g/2005#thumbnail","width":"32","height":"32","src":"\/\/1.bp.blogspot.com\/-g_VzzHzaUw0\/XJ-DogCRhLI\/AAAAAAAAbyc\/zo4GW4KkKNclfUxHeg0jTX5SSQwUkQ15QCK4BGAYYCw\/s220\/Larry%2BMoran.jpg"}}],"thr$in-reply-to":{"xmlns$thr":"http://purl.org/syndication/thread/1.0","href":"https:\/\/sandwalk.blogspot.com\/2020\/11\/why-is-central-dogma-so-hard-to.html","ref":"tag:blogger.com,1999:blog-37148773.post-4761741525215825233","source":"http://www.blogger.com/feeds/37148773/posts/default/4761741525215825233","type":"text/html"},"gd$extendedProperty":[{"name":"blogger.itemClass","value":"pid-886792544"},{"name":"blogger.displayTime","value":"Tuesday, November 17, 2020 2:46:00 PM"}]},{"id":{"$t":"tag:blogger.com,1999:blog-37148773.post-5900263397471005446"},"published":{"$t":"2020-11-17T14:44:34.216-05:00"},"updated":{"$t":"2020-11-17T14:44:34.216-05:00"},"title":{"type":"text","$t":"If you had read my 2007 post this is what you woul..."},"content":{"type":"html","$t":"If you had read my 2007 post this is what you would have seen ...\u003Cbr \/\u003E\u003Cbr \/\u003E\u0026quot;Unfortunately, there’s second version of the Central Dogma that’s very popular even though it’s historically incorrect. This version is the simplistic DNA → RNA → protein pathway that was published by Jim Watson in the first edition of The Molecular Biology of the Gene (Watson, 1965). Watson’s version differs from Crick’s because Watson describes the two-step (DNA → RNA and RNA → protein) pathway as the Central Dogma. It has long been known that these conflicting versions have caused confusion among students and scientists (Darden and Tabery, 2005; Thieffry, 1998). I argue that as teachers we should teach the correct version, or, at the very least, acknowledge that there are conflicting versions of the Central Dogma of Molecular Biology.\u0026quot;\u003Cbr \/\u003E"},"link":[{"rel":"edit","type":"application/atom+xml","href":"https:\/\/www.blogger.com\/feeds\/37148773\/4761741525215825233\/comments\/default\/5900263397471005446"},{"rel":"self","type":"application/atom+xml","href":"https:\/\/www.blogger.com\/feeds\/37148773\/4761741525215825233\/comments\/default\/5900263397471005446"},{"rel":"alternate","type":"text/html","href":"https:\/\/sandwalk.blogspot.com\/2020\/11\/why-is-central-dogma-so-hard-to.html?showComment=1605642274216#c5900263397471005446","title":""},{"rel":"related","type":"application/atom+xml","href":"https:\/\/www.blogger.com\/feeds\/37148773\/4761741525215825233\/comments\/default\/2017101883626346671"}],"author":[{"name":{"$t":"Larry Moran"},"uri":{"$t":"https:\/\/www.blogger.com\/profile\/05756598746605455848"},"email":{"$t":"noreply@blogger.com"},"gd$image":{"rel":"http://schemas.google.com/g/2005#thumbnail","width":"32","height":"32","src":"\/\/1.bp.blogspot.com\/-g_VzzHzaUw0\/XJ-DogCRhLI\/AAAAAAAAbyc\/zo4GW4KkKNclfUxHeg0jTX5SSQwUkQ15QCK4BGAYYCw\/s220\/Larry%2BMoran.jpg"}}],"thr$in-reply-to":{"xmlns$thr":"http://purl.org/syndication/thread/1.0","href":"https:\/\/sandwalk.blogspot.com\/2020\/11\/why-is-central-dogma-so-hard-to.html","ref":"tag:blogger.com,1999:blog-37148773.post-4761741525215825233","source":"http://www.blogger.com/feeds/37148773/posts/default/4761741525215825233","type":"text/html"},"gd$extendedProperty":[{"name":"blogger.itemClass","value":"pid-886792544"},{"name":"blogger.displayTime","value":"Tuesday, November 17, 2020 2:44:00 PM"}]},{"id":{"$t":"tag:blogger.com,1999:blog-37148773.post-2017101883626346671"},"published":{"$t":"2020-11-17T10:52:19.491-05:00"},"updated":{"$t":"2020-11-17T10:52:19.491-05:00"},"title":{"type":"text","$t":"Hi Larry Moran,\n\nthe equivalent ultimately goes ba..."},"content":{"type":"html","$t":"Hi Larry Moran,\u003Cbr \/\u003E\u003Cbr \/\u003Ethe equivalent ultimately goes back to a mistake made by James D. Watson in the first edition of his “Molecular Biology of the Gene” (1965)...\u003Cbr \/\u003E\u003Cbr \/\u003E\u003Cbr \/\u003ECheers,\u003Cbr \/\u003E\u003Cbr \/\u003ELamarck\u003Cbr \/\u003E"},"link":[{"rel":"edit","type":"application/atom+xml","href":"https:\/\/www.blogger.com\/feeds\/37148773\/4761741525215825233\/comments\/default\/2017101883626346671"},{"rel":"self","type":"application/atom+xml","href":"https:\/\/www.blogger.com\/feeds\/37148773\/4761741525215825233\/comments\/default\/2017101883626346671"},{"rel":"alternate","type":"text/html","href":"https:\/\/sandwalk.blogspot.com\/2020\/11\/why-is-central-dogma-so-hard-to.html?showComment=1605628339491#c2017101883626346671","title":""}],"author":[{"name":{"$t":"Lamarck"},"uri":{"$t":"https:\/\/www.blogger.com\/profile\/16658282502276785072"},"email":{"$t":"noreply@blogger.com"},"gd$image":{"rel":"http://schemas.google.com/g/2005#thumbnail","width":"25","height":"32","src":"\/\/4.bp.blogspot.com\/-T-57OJl9pLI\/X1pO-HwP0VI\/AAAAAAAADQU\/NXuNX_f2xEYtRR4dEUlpT2qoME4BZsFdgCK4BGAYYCw\/s1600\/FGH021.jpg"}}],"thr$in-reply-to":{"xmlns$thr":"http://purl.org/syndication/thread/1.0","href":"https:\/\/sandwalk.blogspot.com\/2020\/11\/why-is-central-dogma-so-hard-to.html","ref":"tag:blogger.com,1999:blog-37148773.post-4761741525215825233","source":"http://www.blogger.com/feeds/37148773/posts/default/4761741525215825233","type":"text/html"},"gd$extendedProperty":[{"name":"blogger.itemClass","value":"pid-786365907"},{"name":"blogger.displayTime","value":"Tuesday, November 17, 2020 10:52:00 AM"}]},{"id":{"$t":"tag:blogger.com,1999:blog-37148773.post-2804021365943952146"},"published":{"$t":"2020-11-16T21:04:29.106-05:00"},"updated":{"$t":"2020-11-16T21:04:29.106-05:00"},"title":{"type":"text","$t":"Marcus in 1983 reported that one molecule of RNA, ..."},"content":{"type":"html","$t":"Marcus in 1983 reported that one molecule of RNA, should it find a complementary partner, would suffice to trigger an interferon response (Interferon 5, 115-180). So, say, a coronavirus mRNA \u0026quot;vaccine\u0026quot; is injected and one gets in a host cell that happens to have a complement (perhaps aka \u0026quot;junk RNA\u0026quot;). The dsRNA, courtesy of interferon, enhances MHC protein expression, while the mRNA then shakes itself loose and gets translated. The resulting foreign peptides form pMHC complexes that are displayed at the cell surface just in time to entice a passing T-cell. The rest is history!"},"link":[{"rel":"edit","type":"application/atom+xml","href":"https:\/\/www.blogger.com\/feeds\/37148773\/3734425115430759233\/comments\/default\/2804021365943952146"},{"rel":"self","type":"application/atom+xml","href":"https:\/\/www.blogger.com\/feeds\/37148773\/3734425115430759233\/comments\/default\/2804021365943952146"},{"rel":"alternate","type":"text/html","href":"https:\/\/sandwalk.blogspot.com\/2020\/11\/on-misrepresentation-of-facts-about.html?showComment=1605578669106#c2804021365943952146","title":""},{"rel":"related","type":"application/atom+xml","href":"https:\/\/www.blogger.com\/feeds\/37148773\/3734425115430759233\/comments\/default\/5625368422308967620"}],"author":[{"name":{"$t":"Donald Forsdyke"},"uri":{"$t":"https:\/\/www.blogger.com\/profile\/18038104286639798795"},"email":{"$t":"noreply@blogger.com"},"gd$image":{"rel":"http://schemas.google.com/g/2005#thumbnail","width":"24","height":"32","src":"https:\/\/images-blogger-opensocial.googleusercontent.com\/gadgets\/proxy?url=http:\/\/3.bp.blogspot.com\/-z-gZx9wrKdU\/VTf-lRnEcEI\/AAAAAAAAAJc\/geM7YobW0ro\/s113\/DonaldForsdyke02.jpg\u0026container=blogger\u0026gadget=a\u0026rewriteMime=image\/*"}}],"thr$in-reply-to":{"xmlns$thr":"http://purl.org/syndication/thread/1.0","href":"https:\/\/sandwalk.blogspot.com\/2020\/11\/on-misrepresentation-of-facts-about.html","ref":"tag:blogger.com,1999:blog-37148773.post-3734425115430759233","source":"http://www.blogger.com/feeds/37148773/posts/default/3734425115430759233","type":"text/html"},"gd$extendedProperty":[{"name":"blogger.itemClass","value":"pid-1853642938"},{"name":"blogger.displayTime","value":"Monday, November 16, 2020 9:04:00 PM"}]},{"id":{"$t":"tag:blogger.com,1999:blog-37148773.post-3722120227246920412"},"published":{"$t":"2020-11-16T20:50:58.920-05:00"},"updated":{"$t":"2020-11-16T20:50:58.920-05:00"},"title":{"type":"text","$t":"For some reason I was expecting you to mention a c..."},"content":{"type":"html","$t":"For some reason I was expecting you to mention a case of ambiguity with respect to post-translational modification of proteins by other proteins(or editing of nucleic acid sequences by proteins) as that\u0026#39;s \u003Cem\u003Eusually\u003C\/em\u003E what so-called \u0026quot;exceptions\u0026quot; to the central dogma are claimed to be. \u003Cbr \/\u003E\u003Cbr \/\u003EBut no, this was worse than I had even dared to dream. "},"link":[{"rel":"edit","type":"application/atom+xml","href":"https:\/\/www.blogger.com\/feeds\/37148773\/4761741525215825233\/comments\/default\/3722120227246920412"},{"rel":"self","type":"application/atom+xml","href":"https:\/\/www.blogger.com\/feeds\/37148773\/4761741525215825233\/comments\/default\/3722120227246920412"},{"rel":"alternate","type":"text/html","href":"https:\/\/sandwalk.blogspot.com\/2020\/11\/why-is-central-dogma-so-hard-to.html?showComment=1605577858920#c3722120227246920412","title":""}],"author":[{"name":{"$t":"Mikkel Rumraket Rasmussen"},"uri":{"$t":"https:\/\/www.blogger.com\/profile\/07670550711237457368"},"email":{"$t":"noreply@blogger.com"},"gd$image":{"rel":"http://schemas.google.com/g/2005#thumbnail","width":"33","height":"25","src":"http:\/\/2.bp.blogspot.com\/-SIaUJ4pCpaE\/UaBt7hHdemI\/AAAAAAAAACM\/VHgMmN5IxLE\/s220\/continentaldrift.png"}}],"thr$in-reply-to":{"xmlns$thr":"http://purl.org/syndication/thread/1.0","href":"https:\/\/sandwalk.blogspot.com\/2020\/11\/why-is-central-dogma-so-hard-to.html","ref":"tag:blogger.com,1999:blog-37148773.post-4761741525215825233","source":"http://www.blogger.com/feeds/37148773/posts/default/4761741525215825233","type":"text/html"},"gd$extendedProperty":[{"name":"blogger.itemClass","value":"pid-1643886266"},{"name":"blogger.displayTime","value":"Monday, November 16, 2020 8:50:00 PM"}]},{"id":{"$t":"tag:blogger.com,1999:blog-37148773.post-2288214249272375318"},"published":{"$t":"2020-11-14T16:00:49.127-05:00"},"updated":{"$t":"2020-11-14T16:00:49.127-05:00"},"title":{"type":"text","$t":"Those genes might function by damaging DNA and kil..."},"content":{"type":"html","$t":"Those genes might function by damaging DNA and killing off the cells that contain active endonuclease genes, or by killing off cells with insufficiently robust DNA repair systems, or insufficiently robust DNA error correcting systems to prevent cancer.  \u003Cbr \/\u003E\u003Cbr \/\u003EThe \u0026#39;activity\u0026#39; doesn\u0026#39;t need to be very high to be effective, once per organism lifetime would be enough.\u003Cbr \/\u003E\u003Cbr \/\u003EOnce per gamete lifetime in haploid gametes would also be enough.  Purging deleterious genes in haploid gametes would be quite advantageous.  \u003Cbr \/\u003E\u003Cbr \/\u003EYes, these would be difficult to demonstrate.  \u003Cbr \/\u003E\u003Cbr \/\u003EWe know that endogenous retroviruses have been inhibited by ‘stuff’ that inactivate them.  Presumably the \u0026#39;mechanism(s)\u0026#39; that did that are \u0026#39;features\u0026#39; and not \u0026#39;bugs\u0026#39;.  "},"link":[{"rel":"edit","type":"application/atom+xml","href":"https:\/\/www.blogger.com\/feeds\/37148773\/3734425115430759233\/comments\/default\/2288214249272375318"},{"rel":"self","type":"application/atom+xml","href":"https:\/\/www.blogger.com\/feeds\/37148773\/3734425115430759233\/comments\/default\/2288214249272375318"},{"rel":"alternate","type":"text/html","href":"https:\/\/sandwalk.blogspot.com\/2020\/11\/on-misrepresentation-of-facts-about.html?showComment=1605387649127#c2288214249272375318","title":""},{"rel":"related","type":"application/atom+xml","href":"https:\/\/www.blogger.com\/feeds\/37148773\/3734425115430759233\/comments\/default\/5625368422308967620"}],"author":[{"name":{"$t":"daedalus2u"},"uri":{"$t":"https:\/\/www.blogger.com\/profile\/10416564922288784455"},"email":{"$t":"noreply@blogger.com"},"gd$image":{"rel":"http://schemas.google.com/g/2005#thumbnail","width":"24","height":"32","src":"http:\/\/3.bp.blogspot.com\/_0-KotiogaG0\/SVFZJg3Z-tI\/AAAAAAAAAFI\/C1cM0tAHi0E\/S220\/post+haircut.jpg"}}],"thr$in-reply-to":{"xmlns$thr":"http://purl.org/syndication/thread/1.0","href":"https:\/\/sandwalk.blogspot.com\/2020\/11\/on-misrepresentation-of-facts-about.html","ref":"tag:blogger.com,1999:blog-37148773.post-3734425115430759233","source":"http://www.blogger.com/feeds/37148773/posts/default/3734425115430759233","type":"text/html"},"gd$extendedProperty":[{"name":"blogger.itemClass","value":"pid-919850331"},{"name":"blogger.displayTime","value":"Saturday, November 14, 2020 4:00:00 PM"}]},{"id":{"$t":"tag:blogger.com,1999:blog-37148773.post-3315941336854977964"},"published":{"$t":"2020-11-14T10:47:32.421-05:00"},"updated":{"$t":"2020-11-14T10:47:32.421-05:00"},"title":{"type":"text","$t":"Hi Larry Moran!\n\nNot so bad at all! If you would s..."},"content":{"type":"html","$t":"Hi Larry Moran!\u003Cbr \/\u003E\u003Cbr \/\u003ENot so bad at all! If you would succeed in depicting the metaphor ‘function’ as a form of dynamic biochemical activity, I would wear a shirt with your portrait and laurel wreath...\u003Cbr \/\u003E\u003Cbr \/\u003EHowever, I am afraid that it is not understood which bias is present in the paper in question. In their paper, the authors have finally only made the analogy conclusion that if it is certain that ncRNA can be considered ‘functional’ [\u003Ci\u003Esic!\u003C\/i\u003E] in principle, this could be the case with lncRNA as well. The devil is in the premises...\u003Cbr \/\u003ESome rhetorical questions towards a theory of the gene:\u003Cbr \/\u003E\u003Cbr \/\u003EQ1: If DNA transcribes into junk RNA, is this DNA not junk RNA because it has the \u0026#39;function\u0026#39; to transcribe junk RNA?\u003Cbr \/\u003EQ2: What is the situation here in relation to reverse transcription?\u003Cbr \/\u003EQ3: If junk DNA and junk RNA are conceptually associated with \u0026#39;function\u0026#39;, isn\u0026#39;t it also possible to associate them with junk protein, junk cell, junk organism?\u003Cbr \/\u003EQ4: If a genome is considered functional in its entirety, why is it appropriate not to consider some of its compartments as functional?\u003Cbr \/\u003E\u003Cbr \/\u003E\u003Cbr \/\u003ECheers,\u003Cbr \/\u003E\u003Cbr \/\u003ELamarck\u003Cbr \/\u003E"},"link":[{"rel":"edit","type":"application/atom+xml","href":"https:\/\/www.blogger.com\/feeds\/37148773\/3734425115430759233\/comments\/default\/3315941336854977964"},{"rel":"self","type":"application/atom+xml","href":"https:\/\/www.blogger.com\/feeds\/37148773\/3734425115430759233\/comments\/default\/3315941336854977964"},{"rel":"alternate","type":"text/html","href":"https:\/\/sandwalk.blogspot.com\/2020\/11\/on-misrepresentation-of-facts-about.html?showComment=1605368852421#c3315941336854977964","title":""}],"author":[{"name":{"$t":"Lamarck"},"uri":{"$t":"https:\/\/www.blogger.com\/profile\/16658282502276785072"},"email":{"$t":"noreply@blogger.com"},"gd$image":{"rel":"http://schemas.google.com/g/2005#thumbnail","width":"25","height":"32","src":"\/\/4.bp.blogspot.com\/-T-57OJl9pLI\/X1pO-HwP0VI\/AAAAAAAADQU\/NXuNX_f2xEYtRR4dEUlpT2qoME4BZsFdgCK4BGAYYCw\/s1600\/FGH021.jpg"}}],"thr$in-reply-to":{"xmlns$thr":"http://purl.org/syndication/thread/1.0","href":"https:\/\/sandwalk.blogspot.com\/2020\/11\/on-misrepresentation-of-facts-about.html","ref":"tag:blogger.com,1999:blog-37148773.post-3734425115430759233","source":"http://www.blogger.com/feeds/37148773/posts/default/3734425115430759233","type":"text/html"},"gd$extendedProperty":[{"name":"blogger.itemClass","value":"pid-786365907"},{"name":"blogger.displayTime","value":"Saturday, November 14, 2020 10:47:00 AM"}]},{"id":{"$t":"tag:blogger.com,1999:blog-37148773.post-7032916540402611044"},"published":{"$t":"2020-11-14T10:46:29.875-05:00"},"updated":{"$t":"2020-11-14T10:46:29.875-05:00"},"title":{"type":"text","$t":"Hi Joe Felsenstein!\n\n»Your all-too-lonely struggle..."},"content":{"type":"html","$t":"Hi Joe Felsenstein!\u003Cbr \/\u003E\u003Cbr \/\u003E\u003Ci\u003E»Your all-too-lonely struggle is against the delusion that the cell is perfectly adapted in every respect. As you know, that image ignores the actual processes of adaptive, nonadaptive and maladaptive change.«\u003C\/i\u003E\u003Cbr \/\u003E\u003Cbr \/\u003EOf course I underline the first sentence: Adaptation is qualitative - it is sufficient to maintain the continuity of the germ line. Any organism that succeeds in this is in this respect a resultant solution to the environmental conditions. Thus the germ line is potentially immortal. With regard to the second sentence, I would like to discuss the corresponding topic using the keyword sickle cell anaemia. Or why I seem to have advantages with Type O negative to cope with SARS-CoV-2.\u003Cbr \/\u003E\u003Cbr \/\u003E\u003Cbr \/\u003ECheers,\u003Cbr \/\u003E\u003Cbr \/\u003ELamarck\u003Cbr \/\u003E"},"link":[{"rel":"edit","type":"application/atom+xml","href":"https:\/\/www.blogger.com\/feeds\/37148773\/3734425115430759233\/comments\/default\/7032916540402611044"},{"rel":"self","type":"application/atom+xml","href":"https:\/\/www.blogger.com\/feeds\/37148773\/3734425115430759233\/comments\/default\/7032916540402611044"},{"rel":"alternate","type":"text/html","href":"https:\/\/sandwalk.blogspot.com\/2020\/11\/on-misrepresentation-of-facts-about.html?showComment=1605368789875#c7032916540402611044","title":""},{"rel":"related","type":"application/atom+xml","href":"https:\/\/www.blogger.com\/feeds\/37148773\/3734425115430759233\/comments\/default\/1801648599799814695"}],"author":[{"name":{"$t":"Lamarck"},"uri":{"$t":"https:\/\/www.blogger.com\/profile\/16658282502276785072"},"email":{"$t":"noreply@blogger.com"},"gd$image":{"rel":"http://schemas.google.com/g/2005#thumbnail","width":"25","height":"32","src":"\/\/4.bp.blogspot.com\/-T-57OJl9pLI\/X1pO-HwP0VI\/AAAAAAAADQU\/NXuNX_f2xEYtRR4dEUlpT2qoME4BZsFdgCK4BGAYYCw\/s1600\/FGH021.jpg"}}],"thr$in-reply-to":{"xmlns$thr":"http://purl.org/syndication/thread/1.0","href":"https:\/\/sandwalk.blogspot.com\/2020\/11\/on-misrepresentation-of-facts-about.html","ref":"tag:blogger.com,1999:blog-37148773.post-3734425115430759233","source":"http://www.blogger.com/feeds/37148773/posts/default/3734425115430759233","type":"text/html"},"gd$extendedProperty":[{"name":"blogger.itemClass","value":"pid-786365907"},{"name":"blogger.displayTime","value":"Saturday, November 14, 2020 10:46:00 AM"}]},{"id":{"$t":"tag:blogger.com,1999:blog-37148773.post-5000554788896222732"},"published":{"$t":"2020-11-14T10:45:39.087-05:00"},"updated":{"$t":"2020-11-14T10:45:39.087-05:00"},"title":{"type":"text","$t":"Hi Unknown!\n\n»I have a tangential question - what ..."},"content":{"type":"html","$t":"Hi Unknown!\u003Cbr \/\u003E\u003Cbr \/\u003E\u003Ci\u003E»I have a tangential question - what do you think about the role for alternative transcriptional start sites? Just a cellular error, or something more?«\u003C\/i\u003E\u003Cbr \/\u003E\u003Cbr \/\u003ECertainly you know https:\/\/dx.doi.org\/10.1261%2Frna.035865.112. I especially like this introductory sentence:\u003Cbr \/\u003E\u003Cbr \/\u003E\u003Ci\u003E»Regulation of the proteome is therefore the primary output of signaling pathways that connect cell physiology to internal and external environmental cues.«\u003C\/i\u003E\u003Cbr \/\u003E\u003Cbr \/\u003EFrom the perspective of the proteome this would not be an error of any kind anywhere, but a switch in a dynamic network (“It\u0026#39;s not a bug, it\u0026#39;s a feature”).\u003Cbr \/\u003E\u003Cbr \/\u003E\u003Cbr \/\u003ECheers,\u003Cbr \/\u003E\u003Cbr \/\u003ELamarck\u003Cbr \/\u003E"},"link":[{"rel":"edit","type":"application/atom+xml","href":"https:\/\/www.blogger.com\/feeds\/37148773\/3734425115430759233\/comments\/default\/5000554788896222732"},{"rel":"self","type":"application/atom+xml","href":"https:\/\/www.blogger.com\/feeds\/37148773\/3734425115430759233\/comments\/default\/5000554788896222732"},{"rel":"alternate","type":"text/html","href":"https:\/\/sandwalk.blogspot.com\/2020\/11\/on-misrepresentation-of-facts-about.html?showComment=1605368739087#c5000554788896222732","title":""},{"rel":"related","type":"application/atom+xml","href":"https:\/\/www.blogger.com\/feeds\/37148773\/3734425115430759233\/comments\/default\/2317815735952972786"}],"author":[{"name":{"$t":"Lamarck"},"uri":{"$t":"https:\/\/www.blogger.com\/profile\/16658282502276785072"},"email":{"$t":"noreply@blogger.com"},"gd$image":{"rel":"http://schemas.google.com/g/2005#thumbnail","width":"25","height":"32","src":"\/\/4.bp.blogspot.com\/-T-57OJl9pLI\/X1pO-HwP0VI\/AAAAAAAADQU\/NXuNX_f2xEYtRR4dEUlpT2qoME4BZsFdgCK4BGAYYCw\/s1600\/FGH021.jpg"}}],"thr$in-reply-to":{"xmlns$thr":"http://purl.org/syndication/thread/1.0","href":"https:\/\/sandwalk.blogspot.com\/2020\/11\/on-misrepresentation-of-facts-about.html","ref":"tag:blogger.com,1999:blog-37148773.post-3734425115430759233","source":"http://www.blogger.com/feeds/37148773/posts/default/3734425115430759233","type":"text/html"},"gd$extendedProperty":[{"name":"blogger.itemClass","value":"pid-786365907"},{"name":"blogger.displayTime","value":"Saturday, November 14, 2020 10:45:00 AM"}]},{"id":{"$t":"tag:blogger.com,1999:blog-37148773.post-1801648599799814695"},"published":{"$t":"2020-11-12T12:13:54.879-05:00"},"updated":{"$t":"2020-11-12T12:13:54.879-05:00"},"title":{"type":"text","$t":"As the Australians say \u0026quot;good on you\u0026quot;.  Y..."},"content":{"type":"html","$t":"As the Australians say \u0026quot;good on you\u0026quot;.  Your all-too-lonely struggle is against the delusion that the cell is perfectly adapted in every respect.  As you know, that image ignores the actual processes of adaptive, nonadaptive and maladaptive change.  It is hard to make a dent in this widely-shared delusion, but you are trying.  Applause! "},"link":[{"rel":"edit","type":"application/atom+xml","href":"https:\/\/www.blogger.com\/feeds\/37148773\/3734425115430759233\/comments\/default\/1801648599799814695"},{"rel":"self","type":"application/atom+xml","href":"https:\/\/www.blogger.com\/feeds\/37148773\/3734425115430759233\/comments\/default\/1801648599799814695"},{"rel":"alternate","type":"text/html","href":"https:\/\/sandwalk.blogspot.com\/2020\/11\/on-misrepresentation-of-facts-about.html?showComment=1605201234879#c1801648599799814695","title":""}],"author":[{"name":{"$t":"Joe Felsenstein"},"uri":{"$t":"https:\/\/www.blogger.com\/profile\/06359126552631140000"},"email":{"$t":"noreply@blogger.com"},"gd$image":{"rel":"http://schemas.google.com/g/2005#thumbnail","width":"16","height":"16","src":"https:\/\/img1.blogblog.com\/img\/b16-rounded.gif"}}],"thr$in-reply-to":{"xmlns$thr":"http://purl.org/syndication/thread/1.0","href":"https:\/\/sandwalk.blogspot.com\/2020\/11\/on-misrepresentation-of-facts-about.html","ref":"tag:blogger.com,1999:blog-37148773.post-3734425115430759233","source":"http://www.blogger.com/feeds/37148773/posts/default/3734425115430759233","type":"text/html"},"gd$extendedProperty":[{"name":"blogger.itemClass","value":"pid-1872883924"},{"name":"blogger.displayTime","value":"Thursday, November 12, 2020 12:13:00 PM"}]},{"id":{"$t":"tag:blogger.com,1999:blog-37148773.post-821986588951322186"},"published":{"$t":"2020-11-12T08:09:35.455-05:00"},"updated":{"$t":"2020-11-12T08:09:35.455-05:00"},"title":{"type":"text","$t":"\u0026quot;One copy per cell could be important, if it ..."},"content":{"type":"html","$t":"\u003Cem\u003E\u0026quot;One copy per cell could be important, if it is doing something like inactivating a homing endonuclease gene before it takes over the whole genome.\u0026quot;\u003C\/em\u003E\u003Cbr \/\u003E\u003Cbr \/\u003EThat seems very unlikely. With one or less than one copy per cell (meaning some cells don\u0026#39;t even have a copy some of the time) it would be rather unlikely for that one gene copy to find and deactivate some aberrant molecule before it manages to cause damage. And in any case, there\u0026#39;s zero evidence that noisy transcripts function by \u0026quot;killing off\u0026quot; anything at all. \u003Cbr \/\u003E\u003Cbr \/\u003EThe idea that products of transcriptional noise is somehow still functional makes for a very poor null hypothesis because it\u0026#39;s almost impossible to test in practice. \u003Cbr \/\u003E\u003Cbr \/\u003E\u003Ca href=\"https:\/\/thefinchandpea.com\/2013\/07\/17\/using-a-null-hypothesis-to-find-function-in-the-genome\/\" rel=\"nofollow\"\u003EFinding function in the genome with a null hypothesis\u003C\/a\u003E\u003Cbr \/\u003E\u003Cbr \/\u003E\u003Ca href=\"https:\/\/bmcbiol.biomedcentral.com\/articles\/10.1186\/s12915-016-0338-2?optIn=true\" rel=\"nofollow\"\u003ESplendor and misery of adaptation, or the importance of neutral null for understanding evolution\u003C\/a\u003E"},"link":[{"rel":"edit","type":"application/atom+xml","href":"https:\/\/www.blogger.com\/feeds\/37148773\/3734425115430759233\/comments\/default\/821986588951322186"},{"rel":"self","type":"application/atom+xml","href":"https:\/\/www.blogger.com\/feeds\/37148773\/3734425115430759233\/comments\/default\/821986588951322186"},{"rel":"alternate","type":"text/html","href":"https:\/\/sandwalk.blogspot.com\/2020\/11\/on-misrepresentation-of-facts-about.html?showComment=1605186575455#c821986588951322186","title":""},{"rel":"related","type":"application/atom+xml","href":"https:\/\/www.blogger.com\/feeds\/37148773\/3734425115430759233\/comments\/default\/5625368422308967620"}],"author":[{"name":{"$t":"Mikkel Rumraket Rasmussen"},"uri":{"$t":"https:\/\/www.blogger.com\/profile\/07670550711237457368"},"email":{"$t":"noreply@blogger.com"},"gd$image":{"rel":"http://schemas.google.com/g/2005#thumbnail","width":"33","height":"25","src":"http:\/\/2.bp.blogspot.com\/-SIaUJ4pCpaE\/UaBt7hHdemI\/AAAAAAAAACM\/VHgMmN5IxLE\/s220\/continentaldrift.png"}}],"thr$in-reply-to":{"xmlns$thr":"http://purl.org/syndication/thread/1.0","href":"https:\/\/sandwalk.blogspot.com\/2020\/11\/on-misrepresentation-of-facts-about.html","ref":"tag:blogger.com,1999:blog-37148773.post-3734425115430759233","source":"http://www.blogger.com/feeds/37148773/posts/default/3734425115430759233","type":"text/html"},"gd$extendedProperty":[{"name":"blogger.itemClass","value":"pid-1643886266"},{"name":"blogger.displayTime","value":"Thursday, November 12, 2020 8:09:00 AM"}]},{"id":{"$t":"tag:blogger.com,1999:blog-37148773.post-7877095129239526171"},"published":{"$t":"2020-11-11T21:43:25.455-05:00"},"updated":{"$t":"2020-11-11T21:43:25.455-05:00"},"title":{"type":"text","$t":"One copy per cell could be important, if it is doi..."},"content":{"type":"html","$t":"One copy per cell could be important, if it is doing something like inactivating a homing endonuclease gene before it takes over the whole genome.  \u003Cbr \/\u003E\u003Cbr \/\u003EMaybe that transcriptional \u0026#39;noise\u0026#39; is also a \u0026#39;feature\u0026#39;, to prevent homing endonuclease genes from taking over the whole genome.  Maybe that is what limits the fidelity of eukaryote DNA replication; \u0026#39;killing off\u0026#39; homing endonuclease genes before they take over a species gene pool.  "},"link":[{"rel":"edit","type":"application/atom+xml","href":"https:\/\/www.blogger.com\/feeds\/37148773\/3734425115430759233\/comments\/default\/7877095129239526171"},{"rel":"self","type":"application/atom+xml","href":"https:\/\/www.blogger.com\/feeds\/37148773\/3734425115430759233\/comments\/default\/7877095129239526171"},{"rel":"alternate","type":"text/html","href":"https:\/\/sandwalk.blogspot.com\/2020\/11\/on-misrepresentation-of-facts-about.html?showComment=1605149005455#c7877095129239526171","title":""},{"rel":"related","type":"application/atom+xml","href":"https:\/\/www.blogger.com\/feeds\/37148773\/3734425115430759233\/comments\/default\/5625368422308967620"}],"author":[{"name":{"$t":"daedalus2u"},"uri":{"$t":"https:\/\/www.blogger.com\/profile\/10416564922288784455"},"email":{"$t":"noreply@blogger.com"},"gd$image":{"rel":"http://schemas.google.com/g/2005#thumbnail","width":"24","height":"32","src":"http:\/\/3.bp.blogspot.com\/_0-KotiogaG0\/SVFZJg3Z-tI\/AAAAAAAAAFI\/C1cM0tAHi0E\/S220\/post+haircut.jpg"}}],"thr$in-reply-to":{"xmlns$thr":"http://purl.org/syndication/thread/1.0","href":"https:\/\/sandwalk.blogspot.com\/2020\/11\/on-misrepresentation-of-facts-about.html","ref":"tag:blogger.com,1999:blog-37148773.post-3734425115430759233","source":"http://www.blogger.com/feeds/37148773/posts/default/3734425115430759233","type":"text/html"},"gd$extendedProperty":[{"name":"blogger.itemClass","value":"pid-919850331"},{"name":"blogger.displayTime","value":"Wednesday, November 11, 2020 9:43:00 PM"}]},{"id":{"$t":"tag:blogger.com,1999:blog-37148773.post-5625368422308967620"},"published":{"$t":"2020-11-11T16:25:54.235-05:00"},"updated":{"$t":"2020-11-11T16:25:54.235-05:00"},"title":{"type":"text","$t":"Thanks for this. I harp on this quite a lot with m..."},"content":{"type":"html","$t":"Thanks for this. I harp on this quite a lot with my colleagues. That the genome has a low level bit of tanscriptional noise should just be obvious to anyone who works with genetic systems. Strange things happen in cells. And any transcript that you never see expressed at levels above 1\/cell? No way in hell that is doing anything.\u003Cbr \/\u003E\u003Cbr \/\u003EAnd that doesn\u0026#39;t even take into account that a bunch of that transcriptional noise may also be sequencing and mapping errors"},"link":[{"rel":"edit","type":"application/atom+xml","href":"https:\/\/www.blogger.com\/feeds\/37148773\/3734425115430759233\/comments\/default\/5625368422308967620"},{"rel":"self","type":"application/atom+xml","href":"https:\/\/www.blogger.com\/feeds\/37148773\/3734425115430759233\/comments\/default\/5625368422308967620"},{"rel":"alternate","type":"text/html","href":"https:\/\/sandwalk.blogspot.com\/2020\/11\/on-misrepresentation-of-facts-about.html?showComment=1605129954235#c5625368422308967620","title":""}],"author":[{"name":{"$t":"-DG"},"uri":{"$t":"https:\/\/www.blogger.com\/profile\/16018033631187602248"},"email":{"$t":"noreply@blogger.com"},"gd$image":{"rel":"http://schemas.google.com/g/2005#thumbnail","width":"32","height":"27","src":"http:\/\/4.bp.blogspot.com\/_gN_2ppI8WTk\/TEVviRqr_0I\/AAAAAAAAAE4\/tyPIpkD-RDM\/S220\/IMG_4689.JPG"}}],"thr$in-reply-to":{"xmlns$thr":"http://purl.org/syndication/thread/1.0","href":"https:\/\/sandwalk.blogspot.com\/2020\/11\/on-misrepresentation-of-facts-about.html","ref":"tag:blogger.com,1999:blog-37148773.post-3734425115430759233","source":"http://www.blogger.com/feeds/37148773/posts/default/3734425115430759233","type":"text/html"},"gd$extendedProperty":[{"name":"blogger.itemClass","value":"pid-1868899847"},{"name":"blogger.displayTime","value":"Wednesday, November 11, 2020 4:25:00 PM"}]},{"id":{"$t":"tag:blogger.com,1999:blog-37148773.post-2317815735952972786"},"published":{"$t":"2020-11-11T16:19:37.791-05:00"},"updated":{"$t":"2020-11-11T16:19:37.791-05:00"},"title":{"type":"text","$t":"Great article. I have a tangential question - what..."},"content":{"type":"html","$t":"Great article. I have a tangential question - what do you think about the role for alternative transcriptional start sites? Just a cellular error, or something more? One of our genes of interest seems to doing this (based on 5\u0026#39; RACE), but the literature is decidedly not helpful in decoding what we\u0026#39;re seeing."},"link":[{"rel":"edit","type":"application/atom+xml","href":"https:\/\/www.blogger.com\/feeds\/37148773\/3734425115430759233\/comments\/default\/2317815735952972786"},{"rel":"self","type":"application/atom+xml","href":"https:\/\/www.blogger.com\/feeds\/37148773\/3734425115430759233\/comments\/default\/2317815735952972786"},{"rel":"alternate","type":"text/html","href":"https:\/\/sandwalk.blogspot.com\/2020\/11\/on-misrepresentation-of-facts-about.html?showComment=1605129577791#c2317815735952972786","title":""}],"author":[{"name":{"$t":"Unknown"},"uri":{"$t":"https:\/\/www.blogger.com\/profile\/17334167182522327587"},"email":{"$t":"noreply@blogger.com"},"gd$image":{"rel":"http://schemas.google.com/g/2005#thumbnail","width":"16","height":"16","src":"https:\/\/img1.blogblog.com\/img\/b16-rounded.gif"}}],"thr$in-reply-to":{"xmlns$thr":"http://purl.org/syndication/thread/1.0","href":"https:\/\/sandwalk.blogspot.com\/2020\/11\/on-misrepresentation-of-facts-about.html","ref":"tag:blogger.com,1999:blog-37148773.post-3734425115430759233","source":"http://www.blogger.com/feeds/37148773/posts/default/3734425115430759233","type":"text/html"},"gd$extendedProperty":[{"name":"blogger.itemClass","value":"pid-15735168"},{"name":"blogger.displayTime","value":"Wednesday, November 11, 2020 4:19:00 PM"}]},{"id":{"$t":"tag:blogger.com,1999:blog-37148773.post-7636867704615056226"},"published":{"$t":"2020-11-10T17:53:09.561-05:00"},"updated":{"$t":"2020-11-10T17:53:09.561-05:00"},"title":{"type":"text","$t":"“Duckbills evolved in North America and eventually..."},"content":{"type":"html","$t":"\u003Ci\u003E“Duckbills evolved in North America and eventually spread to South America, Asia, and Europe. Because Africa was an island continent in the Late Cretaceous, isolated by deep seaways, it seemed impossible for duckbills to get there.\u003Cbr \/\u003E\u003Cbr \/\u003EThe discovery of the new fossil in a mine a few hours from Casablanca was “about the last thing in the world you would expect,” said Dr Nicholas Longrich, of the Milner Centre for Evolution at the University of Bath, who led the study. Dr Longrich said: “It was completely out of place, like finding a kangaroo in Scotland. Africa was completely isolated by water – so how did they get there?” ”\u003C\/i\u003E\u003Cbr \/\u003E\u003Cbr \/\u003EApply the scientific method, and get a brilliant, insightful answer:\u003Cbr \/\u003E\u003Cbr \/\u003E\u003Ci\u003E“Because Africa was isolated by deep oceans at the time, duckbills must have crossed hundreds of kilometres of open water- rafting on debris, floating, or swimming – to colonise the continent. Duckbills were probably powerful swimmers – they had large tails and powerful legs, and are often found in river deposits and marine rocks, so they may have simply swum the distance. \u003Cbr \/\u003E\u003Cbr \/\u003E“Sherlock Holmes said, once you eliminate the impossible, whatever remains, no matter how improbable, must be the truth,” said Longrich. “It was impossible to walk to Africa. These dinosaurs evolved long after continental drift split the continents, and we have no evidence of land bridges. The geology tells us Africa was isolated by oceans. If so, the only way to get there is by water.”\u003C\/i\u003E\u003Cbr \/\u003E\u003Cbr \/\u003EI love watching evolutionary scientists solving tough problems.\u003Cbr \/\u003E\u003Cbr \/\u003E\u003Ci\u003E“Over millions of years,” said Longrich, “Once-in-a-century events are likely to happen many times.”\u003C\/i\u003E\u003Cbr \/\u003Ehttps:\/\/www.heritagedaily.com\/2020\/11\/the-first-duckbill-dinosaur-fossil-from-africa-hints-at-how-dinosaurs-once-crossed-oceans\/136056 "},"link":[{"rel":"edit","type":"application/atom+xml","href":"https:\/\/www.blogger.com\/feeds\/37148773\/3483581682344064252\/comments\/default\/7636867704615056226"},{"rel":"self","type":"application/atom+xml","href":"https:\/\/www.blogger.com\/feeds\/37148773\/3483581682344064252\/comments\/default\/7636867704615056226"},{"rel":"alternate","type":"text/html","href":"https:\/\/sandwalk.blogspot.com\/2020\/10\/undergraduate-education-in-biology-no.html?showComment=1605048789561#c7636867704615056226","title":""},{"rel":"related","type":"application/atom+xml","href":"https:\/\/www.blogger.com\/feeds\/37148773\/3483581682344064252\/comments\/default\/3980845448350684265"}],"author":[{"name":{"$t":"txpiper"},"uri":{"$t":"https:\/\/www.blogger.com\/profile\/03645156881353741058"},"email":{"$t":"noreply@blogger.com"},"gd$image":{"rel":"http://schemas.google.com/g/2005#thumbnail","width":"16","height":"16","src":"https:\/\/img1.blogblog.com\/img\/b16-rounded.gif"}}],"thr$in-reply-to":{"xmlns$thr":"http://purl.org/syndication/thread/1.0","href":"https:\/\/sandwalk.blogspot.com\/2020\/10\/undergraduate-education-in-biology-no.html","ref":"tag:blogger.com,1999:blog-37148773.post-3483581682344064252","source":"http://www.blogger.com/feeds/37148773/posts/default/3483581682344064252","type":"text/html"},"gd$extendedProperty":[{"name":"blogger.itemClass","value":"pid-929760727"},{"name":"blogger.displayTime","value":"Tuesday, November 10, 2020 5:53:00 PM"}]},{"id":{"$t":"tag:blogger.com,1999:blog-37148773.post-1995310954847969289"},"published":{"$t":"2020-11-08T15:09:50.197-05:00"},"updated":{"$t":"2020-11-08T15:09:50.197-05:00"},"title":{"type":"text","$t":"Produce the evidence bearing on the claims about m..."},"content":{"type":"html","$t":"Produce the evidence bearing on the claims about mutations, and we\u0026#39;ll see. "},"link":[{"rel":"edit","type":"application/atom+xml","href":"https:\/\/www.blogger.com\/feeds\/37148773\/3483581682344064252\/comments\/default\/1995310954847969289"},{"rel":"self","type":"application/atom+xml","href":"https:\/\/www.blogger.com\/feeds\/37148773\/3483581682344064252\/comments\/default\/1995310954847969289"},{"rel":"alternate","type":"text/html","href":"https:\/\/sandwalk.blogspot.com\/2020\/10\/undergraduate-education-in-biology-no.html?showComment=1604866190197#c1995310954847969289","title":""},{"rel":"related","type":"application/atom+xml","href":"https:\/\/www.blogger.com\/feeds\/37148773\/3483581682344064252\/comments\/default\/3980845448350684265"}],"author":[{"name":{"$t":"txpiper"},"uri":{"$t":"https:\/\/www.blogger.com\/profile\/03645156881353741058"},"email":{"$t":"noreply@blogger.com"},"gd$image":{"rel":"http://schemas.google.com/g/2005#thumbnail","width":"16","height":"16","src":"https:\/\/img1.blogblog.com\/img\/b16-rounded.gif"}}],"thr$in-reply-to":{"xmlns$thr":"http://purl.org/syndication/thread/1.0","href":"https:\/\/sandwalk.blogspot.com\/2020\/10\/undergraduate-education-in-biology-no.html","ref":"tag:blogger.com,1999:blog-37148773.post-3483581682344064252","source":"http://www.blogger.com/feeds/37148773/posts/default/3483581682344064252","type":"text/html"},"gd$extendedProperty":[{"name":"blogger.itemClass","value":"pid-929760727"},{"name":"blogger.displayTime","value":"Sunday, November 08, 2020 3:09:00 PM"}]},{"id":{"$t":"tag:blogger.com,1999:blog-37148773.post-4741702177592237748"},"published":{"$t":"2020-11-08T11:52:11.806-05:00"},"updated":{"$t":"2020-11-08T11:52:11.806-05:00"},"title":{"type":"text","$t":"\u0026quot;If they understand how science generates and..."},"content":{"type":"html","$t":"\u0026quot;If they understand how science generates and assesses evidence bearing on these claims, they possess analytical methods and critical thinking skills that are relevant to a wide variety of facts and concepts and can be used in a wide variety of contexts.”\u0026quot;\u003Cbr \/\u003E\u003Cbr \/\u003EAs you\u0026#39;ve repeatedly demonstrated, you possess none of those skills txpiper"},"link":[{"rel":"edit","type":"application/atom+xml","href":"https:\/\/www.blogger.com\/feeds\/37148773\/3483581682344064252\/comments\/default\/4741702177592237748"},{"rel":"self","type":"application/atom+xml","href":"https:\/\/www.blogger.com\/feeds\/37148773\/3483581682344064252\/comments\/default\/4741702177592237748"},{"rel":"alternate","type":"text/html","href":"https:\/\/sandwalk.blogspot.com\/2020\/10\/undergraduate-education-in-biology-no.html?showComment=1604854331806#c4741702177592237748","title":""},{"rel":"related","type":"application/atom+xml","href":"https:\/\/www.blogger.com\/feeds\/37148773\/3483581682344064252\/comments\/default\/3980845448350684265"}],"author":[{"name":{"$t":"dean"},"uri":{"$t":"https:\/\/www.blogger.com\/profile\/08279929296814513986"},"email":{"$t":"noreply@blogger.com"},"gd$image":{"rel":"http://schemas.google.com/g/2005#thumbnail","width":"16","height":"16","src":"https:\/\/img1.blogblog.com\/img\/b16-rounded.gif"}}],"thr$in-reply-to":{"xmlns$thr":"http://purl.org/syndication/thread/1.0","href":"https:\/\/sandwalk.blogspot.com\/2020\/10\/undergraduate-education-in-biology-no.html","ref":"tag:blogger.com,1999:blog-37148773.post-3483581682344064252","source":"http://www.blogger.com/feeds/37148773/posts/default/3483581682344064252","type":"text/html"},"gd$extendedProperty":[{"name":"blogger.itemClass","value":"pid-430226920"},{"name":"blogger.displayTime","value":"Sunday, November 08, 2020 11:52:00 AM"}]},{"id":{"$t":"tag:blogger.com,1999:blog-37148773.post-7581508740108820060"},"published":{"$t":"2020-11-05T13:50:54.514-05:00"},"updated":{"$t":"2020-11-05T13:50:54.514-05:00"},"title":{"type":"text","$t":"\u0026quot;People often encounter claims that something..."},"content":{"type":"html","$t":"\u003Cb\u003E\u003Ci\u003E\u0026quot;People often encounter claims that something is scientifically known. If they understand how science generates and assesses evidence bearing on these claims, they possess analytical methods and critical thinking skills that are relevant to a wide variety of facts and concepts and can be used in a wide variety of contexts.”\u003C\/i\u003E\u003Cbr \/\u003E\u003Cbr \/\u003ENational Science Foundation, Science and Technology Indicators, 2008\u003C\/b\u003E\u003Cbr \/\u003E\u003Cbr \/\u003EIndeed. \u003Cbr \/\u003E"},"link":[{"rel":"edit","type":"application/atom+xml","href":"https:\/\/www.blogger.com\/feeds\/37148773\/3483581682344064252\/comments\/default\/7581508740108820060"},{"rel":"self","type":"application/atom+xml","href":"https:\/\/www.blogger.com\/feeds\/37148773\/3483581682344064252\/comments\/default\/7581508740108820060"},{"rel":"alternate","type":"text/html","href":"https:\/\/sandwalk.blogspot.com\/2020\/10\/undergraduate-education-in-biology-no.html?showComment=1604602254514#c7581508740108820060","title":""},{"rel":"related","type":"application/atom+xml","href":"https:\/\/www.blogger.com\/feeds\/37148773\/3483581682344064252\/comments\/default\/3980845448350684265"}],"author":[{"name":{"$t":"txpiper"},"uri":{"$t":"https:\/\/www.blogger.com\/profile\/03645156881353741058"},"email":{"$t":"noreply@blogger.com"},"gd$image":{"rel":"http://schemas.google.com/g/2005#thumbnail","width":"16","height":"16","src":"https:\/\/img1.blogblog.com\/img\/b16-rounded.gif"}}],"thr$in-reply-to":{"xmlns$thr":"http://purl.org/syndication/thread/1.0","href":"https:\/\/sandwalk.blogspot.com\/2020\/10\/undergraduate-education-in-biology-no.html","ref":"tag:blogger.com,1999:blog-37148773.post-3483581682344064252","source":"http://www.blogger.com/feeds/37148773/posts/default/3483581682344064252","type":"text/html"},"gd$extendedProperty":[{"name":"blogger.itemClass","value":"pid-929760727"},{"name":"blogger.displayTime","value":"Thursday, November 05, 2020 1:50:00 PM"}]},{"id":{"$t":"tag:blogger.com,1999:blog-37148773.post-3941689414684488816"},"published":{"$t":"2020-11-05T10:29:51.906-05:00"},"updated":{"$t":"2020-11-05T10:29:51.906-05:00"},"title":{"type":"text","$t":"You people should be embarrassed. I wish this exch..."},"content":{"type":"html","$t":"You people should be embarrassed. I wish this exchange had occurred in front of an auditorium full of high school students."},"link":[{"rel":"edit","type":"application/atom+xml","href":"https:\/\/www.blogger.com\/feeds\/37148773\/3483581682344064252\/comments\/default\/3941689414684488816"},{"rel":"self","type":"application/atom+xml","href":"https:\/\/www.blogger.com\/feeds\/37148773\/3483581682344064252\/comments\/default\/3941689414684488816"},{"rel":"alternate","type":"text/html","href":"https:\/\/sandwalk.blogspot.com\/2020\/10\/undergraduate-education-in-biology-no.html?showComment=1604590191906#c3941689414684488816","title":""},{"rel":"related","type":"application/atom+xml","href":"https:\/\/www.blogger.com\/feeds\/37148773\/3483581682344064252\/comments\/default\/3980845448350684265"}],"author":[{"name":{"$t":"txpiper"},"uri":{"$t":"https:\/\/www.blogger.com\/profile\/03645156881353741058"},"email":{"$t":"noreply@blogger.com"},"gd$image":{"rel":"http://schemas.google.com/g/2005#thumbnail","width":"16","height":"16","src":"https:\/\/img1.blogblog.com\/img\/b16-rounded.gif"}}],"thr$in-reply-to":{"xmlns$thr":"http://purl.org/syndication/thread/1.0","href":"https:\/\/sandwalk.blogspot.com\/2020\/10\/undergraduate-education-in-biology-no.html","ref":"tag:blogger.com,1999:blog-37148773.post-3483581682344064252","source":"http://www.blogger.com/feeds/37148773/posts/default/3483581682344064252","type":"text/html"},"gd$extendedProperty":[{"name":"blogger.itemClass","value":"pid-929760727"},{"name":"blogger.displayTime","value":"Thursday, November 05, 2020 10:29:00 AM"}]},{"id":{"$t":"tag:blogger.com,1999:blog-37148773.post-6118755457173584344"},"published":{"$t":"2020-11-05T08:45:50.124-05:00"},"updated":{"$t":"2020-11-05T08:45:50.124-05:00"},"title":{"type":"text","$t":"Hi Texas Pied Piper!\n\n»I am asking you about the m..."},"content":{"type":"html","$t":"Hi Texas Pied Piper!\u003Cbr \/\u003E\u003Cbr \/\u003E\u003Ci\u003E»I am asking you about the most fundamental aspect of your theory; the process responsible for the supposed development of absolutely everything biological that has ever existed. And all you have is doubletalk.«\u003C\/i\u003E\u003Cbr \/\u003E\u003Cbr \/\u003EYou have your problems with the truth. Especially towards yourself. Because you would not be here if the above was really your view, would you?\u003Cbr \/\u003E\u003Cbr \/\u003EWhat do you think in this context about Augustine of Hippo judging the lie as the decision for self-divisiveness carried out with as expression of a turning away from God? According to his view, all human knowledge of truth is based on an irradiation of the unchanging divine light. Therefore, the deliberate deviation from the source of truth given with the phenomenon of the double heart can only come to stand as rebellion against God. Consequently, every lie is inevitably a sin and therefore inevitably results in the loss of eternal life.\u003Cbr \/\u003E\u003Cbr \/\u003EAnd as for your consistent straw man argument: The central element of a theory of evolution is the mutability of species. From this we derive kinship. And this can be detected by theory-based observation.\u003Cbr \/\u003E\u003Cbr \/\u003E\u003Ci\u003E»No, you simply have a low threshold for what constitutes proof. Your kind of science does not ask for empirical evidence.«\u003C\/i\u003E\u003Cbr \/\u003E\u003Cbr \/\u003EYou run away from “empirical evidence” like the craven coward that you are. Perhaps it is because you simply have no threshold for your literal understanding of the Bible, which is evidence. And so better you take care of my case. Certainly some members of the \u0026#39;Evangelical Orthodox Church\u0026#39; know for example 1 Thess. 5:21, Ex 20:16 or 1 Petr. 3:15. In this sense:\u003Cbr \/\u003E\u003Cbr \/\u003EQ1: To check your honesty to the ratio: Is it right that what is literally written in the Bible is so given by God and that it is above all reason, logic and scientific knowledge?\u003Cbr \/\u003EQ2: To check your faith: Assuming that evolution is true, would you still believe in the God of the Bible like the majority of Christians?\u003Cbr \/\u003EQ3: To check your scientific skills: Show why or why not the genetic fingerprint is suitable as a paternity test.\u003Cbr \/\u003E\u003Cbr \/\u003E\u003Cbr \/\u003ECheers,\u003Cbr \/\u003E\u003Cbr \/\u003ELamarck\u003Cbr \/\u003E"},"link":[{"rel":"edit","type":"application/atom+xml","href":"https:\/\/www.blogger.com\/feeds\/37148773\/3483581682344064252\/comments\/default\/6118755457173584344"},{"rel":"self","type":"application/atom+xml","href":"https:\/\/www.blogger.com\/feeds\/37148773\/3483581682344064252\/comments\/default\/6118755457173584344"},{"rel":"alternate","type":"text/html","href":"https:\/\/sandwalk.blogspot.com\/2020\/10\/undergraduate-education-in-biology-no.html?showComment=1604583950124#c6118755457173584344","title":""},{"rel":"related","type":"application/atom+xml","href":"https:\/\/www.blogger.com\/feeds\/37148773\/3483581682344064252\/comments\/default\/3980845448350684265"}],"author":[{"name":{"$t":"Lamarck"},"uri":{"$t":"https:\/\/www.blogger.com\/profile\/16658282502276785072"},"email":{"$t":"noreply@blogger.com"},"gd$image":{"rel":"http://schemas.google.com/g/2005#thumbnail","width":"25","height":"32","src":"\/\/4.bp.blogspot.com\/-T-57OJl9pLI\/X1pO-HwP0VI\/AAAAAAAADQU\/NXuNX_f2xEYtRR4dEUlpT2qoME4BZsFdgCK4BGAYYCw\/s1600\/FGH021.jpg"}}],"thr$in-reply-to":{"xmlns$thr":"http://purl.org/syndication/thread/1.0","href":"https:\/\/sandwalk.blogspot.com\/2020\/10\/undergraduate-education-in-biology-no.html","ref":"tag:blogger.com,1999:blog-37148773.post-3483581682344064252","source":"http://www.blogger.com/feeds/37148773/posts/default/3483581682344064252","type":"text/html"},"gd$extendedProperty":[{"name":"blogger.itemClass","value":"pid-786365907"},{"name":"blogger.displayTime","value":"Thursday, November 05, 2020 8:45:00 AM"}]},{"id":{"$t":"tag:blogger.com,1999:blog-37148773.post-3826238183921961919"},"published":{"$t":"2020-11-05T01:50:28.135-05:00"},"updated":{"$t":"2020-11-05T01:50:28.135-05:00"},"title":{"type":"text","$t":"”An example of how to establish with scientific ce..."},"content":{"type":"html","$t":"\u003Ci\u003E”An example of how to establish with scientific certainty that evolution is true, I have given above.”\u003C\/i\u003E\u003Cbr \/\u003E\u003Cbr \/\u003ENo, you simply have a low threshold for what constitutes proof. Your kind of science does not ask for empirical evidence.\u003Cbr \/\u003E\u003Cbr \/\u003E==\u003Cbr \/\u003E\u003Cbr \/\u003E\u003Ci\u003E”…why can\u0026#39;t you stand the fact that there is evolution?”\u003C\/i\u003E\u003Cbr \/\u003E\u003Cbr \/\u003EI am asking you about the most fundamental aspect of your theory; the process responsible for the supposed development of absolutely everything biological that has ever existed. And all you have is doubletalk."},"link":[{"rel":"edit","type":"application/atom+xml","href":"https:\/\/www.blogger.com\/feeds\/37148773\/3483581682344064252\/comments\/default\/3826238183921961919"},{"rel":"self","type":"application/atom+xml","href":"https:\/\/www.blogger.com\/feeds\/37148773\/3483581682344064252\/comments\/default\/3826238183921961919"},{"rel":"alternate","type":"text/html","href":"https:\/\/sandwalk.blogspot.com\/2020\/10\/undergraduate-education-in-biology-no.html?showComment=1604559028135#c3826238183921961919","title":""},{"rel":"related","type":"application/atom+xml","href":"https:\/\/www.blogger.com\/feeds\/37148773\/3483581682344064252\/comments\/default\/3980845448350684265"}],"author":[{"name":{"$t":"txpiper"},"uri":{"$t":"https:\/\/www.blogger.com\/profile\/03645156881353741058"},"email":{"$t":"noreply@blogger.com"},"gd$image":{"rel":"http://schemas.google.com/g/2005#thumbnail","width":"16","height":"16","src":"https:\/\/img1.blogblog.com\/img\/b16-rounded.gif"}}],"thr$in-reply-to":{"xmlns$thr":"http://purl.org/syndication/thread/1.0","href":"https:\/\/sandwalk.blogspot.com\/2020\/10\/undergraduate-education-in-biology-no.html","ref":"tag:blogger.com,1999:blog-37148773.post-3483581682344064252","source":"http://www.blogger.com/feeds/37148773/posts/default/3483581682344064252","type":"text/html"},"gd$extendedProperty":[{"name":"blogger.itemClass","value":"pid-929760727"},{"name":"blogger.displayTime","value":"Thursday, November 05, 2020 1:50:00 AM"}]},{"id":{"$t":"tag:blogger.com,1999:blog-37148773.post-7691789907825120596"},"published":{"$t":"2020-11-04T18:30:00.778-05:00"},"updated":{"$t":"2020-11-04T18:30:00.778-05:00"},"title":{"type":"text","$t":"Hi Texas Pied Piper!\n\n»I\u0026#39;m embarrassed for you..."},"content":{"type":"html","$t":"Hi Texas Pied Piper!\u003Cbr \/\u003E\u003Cbr \/\u003E\u003Ci\u003E»I\u0026#39;m embarrassed for you.«\u003C\/i\u003E\u003Cbr \/\u003E\u003Cbr \/\u003EThe easily embarrassed doesn\u0026#39;t learn:\u003Cbr \/\u003E\u003Cbr \/\u003E\u003Ci\u003E»\u003Cb\u003EAnswering the question: What is enlightenment?\u003C\/b\u003E\u003Cbr \/\u003EEnlightenment is man\u0026#39;s exit from his self-inflicted mental immaturity. Mental immaturity is the inability to use one\u0026#39;s intellect without the guidance of another. This mental immaturity is self-inflicted if the cause of it lies not in the lack of understanding, but in the resolution and courage to make use of it without the guidance of another.\u003C\/i\u003E Sapere aude! \u003Ci\u003EHave the courage to make use of your own intellect! is thus the motto of the Enlightenment.\u003Cbr \/\u003E\u003Cbr \/\u003ELaziness and cowardice are the reasons why so great a part of men, having long since freed nature from foreign guidance (\u003C\/i\u003Enaturaliter maiorennes\u003Ci\u003E), nevertheless like to remain in mental immaturity throughout their lives; and why it is so easy for others to raise themselves up as their guardians. It is so convenient to be in mental immaturity. [...]«\u003C\/i\u003E [Kant, Immanuel (1784): Beantwortung der Frage: Was ist Aufklärung? Berlinische Monatsschrift, pp. 481-482 (Translation by ‘Lamarck’).]\u003Cbr \/\u003E\u003Cbr \/\u003E\u003Cbr \/\u003E\u003Ci\u003E»Lamarck\u0026#39;s education, as it pertains to evolutionary development, is like knowing all there is to know about Superman or Star Trek.«\u003C\/i\u003E\u003Cbr \/\u003E\u003Cbr \/\u003ERight: I love mythologies. And there is a good reason why it is called Superman here and not \u003Ci\u003E“Ordinary guy. Orthodox evangelical, dispensationalist, literalist Bible thumper”.\u003C\/i\u003E And in Star Trek II \u0026amp; III even the term ‘Genesis’ appears...\u003Cbr \/\u003E\u003Cbr \/\u003E\u003Cbr \/\u003E\u003Ci\u003E»There are no studies that show how random mutations can incrementally accumulate to form complex biological specialties.«\u003C\/i\u003E\u003Cbr \/\u003E\u003Cbr \/\u003EI will take your statement as literally as you do the Bible, so I\u0026#39;m pretty simple-minded: Right! So what? An example of how to establish with scientific certainty that evolution is true, I have given above.\u003Cbr \/\u003E\u003Cbr \/\u003E\u003Ci\u003E»It is not about things that have been discovered.«\u003C\/i\u003E\u003Cbr \/\u003E\u003Cbr \/\u003EI know you\u0026#39;re desperate. But why can\u0026#39;t you stand the fact that there is evolution? Is it your mental immaturity?\u003Cbr \/\u003E\u003Cbr \/\u003E\u003Cbr \/\u003E\u003Ci\u003E»It is just about what people like and choose to believe.«\u003C\/i\u003E\u003Cbr \/\u003E\u003Cbr \/\u003ELet\u0026#39;s put it this way: science is better than bad sex and somehow still contributes to species survival. Even for the benefit of the stupid...\u003Cbr \/\u003E\u003Cbr \/\u003E\u003Cbr \/\u003ECheers,\u003Cbr \/\u003E\u003Cbr \/\u003ELamarck\u003Cbr \/\u003E"},"link":[{"rel":"edit","type":"application/atom+xml","href":"https:\/\/www.blogger.com\/feeds\/37148773\/3483581682344064252\/comments\/default\/7691789907825120596"},{"rel":"self","type":"application/atom+xml","href":"https:\/\/www.blogger.com\/feeds\/37148773\/3483581682344064252\/comments\/default\/7691789907825120596"},{"rel":"alternate","type":"text/html","href":"https:\/\/sandwalk.blogspot.com\/2020\/10\/undergraduate-education-in-biology-no.html?showComment=1604532600778#c7691789907825120596","title":""},{"rel":"related","type":"application/atom+xml","href":"https:\/\/www.blogger.com\/feeds\/37148773\/3483581682344064252\/comments\/default\/3980845448350684265"}],"author":[{"name":{"$t":"Lamarck"},"uri":{"$t":"https:\/\/www.blogger.com\/profile\/16658282502276785072"},"email":{"$t":"noreply@blogger.com"},"gd$image":{"rel":"http://schemas.google.com/g/2005#thumbnail","width":"25","height":"32","src":"\/\/4.bp.blogspot.com\/-T-57OJl9pLI\/X1pO-HwP0VI\/AAAAAAAADQU\/NXuNX_f2xEYtRR4dEUlpT2qoME4BZsFdgCK4BGAYYCw\/s1600\/FGH021.jpg"}}],"thr$in-reply-to":{"xmlns$thr":"http://purl.org/syndication/thread/1.0","href":"https:\/\/sandwalk.blogspot.com\/2020\/10\/undergraduate-education-in-biology-no.html","ref":"tag:blogger.com,1999:blog-37148773.post-3483581682344064252","source":"http://www.blogger.com/feeds/37148773/posts/default/3483581682344064252","type":"text/html"},"gd$extendedProperty":[{"name":"blogger.itemClass","value":"pid-786365907"},{"name":"blogger.displayTime","value":"Wednesday, November 04, 2020 6:30:00 PM"}]},{"id":{"$t":"tag:blogger.com,1999:blog-37148773.post-786609738836294703"},"published":{"$t":"2020-11-03T14:39:46.770-05:00"},"updated":{"$t":"2020-11-03T14:39:46.770-05:00"},"title":{"type":"text","$t":"The second paragraph of my last post should read:\n..."},"content":{"type":"html","$t":"The second paragraph of my last post should read:\u003Cbr \/\u003E\u003Cbr \/\u003ELamarck\u0026#39;s education, \u003Ci\u003Eas it pertains to evolutionary development\u003C\/i\u003E, is like knowing all there is to know about Superman or Star Trek. It is not about things that have been discovered. It is just about what people like and choose to believe.\u003Cbr \/\u003E"},"link":[{"rel":"edit","type":"application/atom+xml","href":"https:\/\/www.blogger.com\/feeds\/37148773\/3483581682344064252\/comments\/default\/786609738836294703"},{"rel":"self","type":"application/atom+xml","href":"https:\/\/www.blogger.com\/feeds\/37148773\/3483581682344064252\/comments\/default\/786609738836294703"},{"rel":"alternate","type":"text/html","href":"https:\/\/sandwalk.blogspot.com\/2020\/10\/undergraduate-education-in-biology-no.html?showComment=1604432386770#c786609738836294703","title":""},{"rel":"related","type":"application/atom+xml","href":"https:\/\/www.blogger.com\/feeds\/37148773\/3483581682344064252\/comments\/default\/3980845448350684265"}],"author":[{"name":{"$t":"txpiper"},"uri":{"$t":"https:\/\/www.blogger.com\/profile\/03645156881353741058"},"email":{"$t":"noreply@blogger.com"},"gd$image":{"rel":"http://schemas.google.com/g/2005#thumbnail","width":"16","height":"16","src":"https:\/\/img1.blogblog.com\/img\/b16-rounded.gif"}}],"thr$in-reply-to":{"xmlns$thr":"http://purl.org/syndication/thread/1.0","href":"https:\/\/sandwalk.blogspot.com\/2020\/10\/undergraduate-education-in-biology-no.html","ref":"tag:blogger.com,1999:blog-37148773.post-3483581682344064252","source":"http://www.blogger.com/feeds/37148773/posts/default/3483581682344064252","type":"text/html"},"gd$extendedProperty":[{"name":"blogger.itemClass","value":"pid-929760727"},{"name":"blogger.displayTime","value":"Tuesday, November 03, 2020 2:39:00 PM"}]},{"id":{"$t":"tag:blogger.com,1999:blog-37148773.post-6357024837351418372"},"published":{"$t":"2020-11-03T13:55:59.045-05:00"},"updated":{"$t":"2020-11-03T13:55:59.045-05:00"},"title":{"type":"text","$t":"They offered nothing. There are no studies that sh..."},"content":{"type":"html","$t":"They offered nothing. There are no studies that show how random mutations can incrementally accumulate to form complex biological specialties. There are no observations, measurements, experiments or testing, so there is no science. You can prove me wrong by providing links to papers that deal specifically with that supposed process. But you will not. There are none.\u003Cbr \/\u003E\u003Cbr \/\u003ELamarck\u0026#39;s education is like knowing all there is to know about Superman or Star Trek. It is not about things that have been discovered. It is just about what people like and choose to believe.\u003Cbr \/\u003E\u003Cbr \/\u003E"},"link":[{"rel":"edit","type":"application/atom+xml","href":"https:\/\/www.blogger.com\/feeds\/37148773\/3483581682344064252\/comments\/default\/6357024837351418372"},{"rel":"self","type":"application/atom+xml","href":"https:\/\/www.blogger.com\/feeds\/37148773\/3483581682344064252\/comments\/default\/6357024837351418372"},{"rel":"alternate","type":"text/html","href":"https:\/\/sandwalk.blogspot.com\/2020\/10\/undergraduate-education-in-biology-no.html?showComment=1604429759045#c6357024837351418372","title":""},{"rel":"related","type":"application/atom+xml","href":"https:\/\/www.blogger.com\/feeds\/37148773\/3483581682344064252\/comments\/default\/3980845448350684265"}],"author":[{"name":{"$t":"txpiper"},"uri":{"$t":"https:\/\/www.blogger.com\/profile\/03645156881353741058"},"email":{"$t":"noreply@blogger.com"},"gd$image":{"rel":"http://schemas.google.com/g/2005#thumbnail","width":"16","height":"16","src":"https:\/\/img1.blogblog.com\/img\/b16-rounded.gif"}}],"thr$in-reply-to":{"xmlns$thr":"http://purl.org/syndication/thread/1.0","href":"https:\/\/sandwalk.blogspot.com\/2020\/10\/undergraduate-education-in-biology-no.html","ref":"tag:blogger.com,1999:blog-37148773.post-3483581682344064252","source":"http://www.blogger.com/feeds/37148773/posts/default/3483581682344064252","type":"text/html"},"gd$extendedProperty":[{"name":"blogger.itemClass","value":"pid-929760727"},{"name":"blogger.displayTime","value":"Tuesday, November 03, 2020 1:55:00 PM"}]},{"id":{"$t":"tag:blogger.com,1999:blog-37148773.post-775464350110360221"},"published":{"$t":"2020-11-03T13:34:40.622-05:00"},"updated":{"$t":"2020-11-03T13:34:40.622-05:00"},"title":{"type":"text","$t":"\u0026quot;Where is the science? \u0026quot;\n\nAll around you..."},"content":{"type":"html","$t":"\u0026quot;Where is the science? \u0026quot;\u003Cbr \/\u003E\u003Cbr \/\u003EAll around you in their responses and in print. The fact that you simply choose to stick fingers in your ears and put blinders on your eyes while chanting \u0026quot;nuh-uh, that\u0026#39;s not science\u0026quot; is irrelevant."},"link":[{"rel":"edit","type":"application/atom+xml","href":"https:\/\/www.blogger.com\/feeds\/37148773\/3483581682344064252\/comments\/default\/775464350110360221"},{"rel":"self","type":"application/atom+xml","href":"https:\/\/www.blogger.com\/feeds\/37148773\/3483581682344064252\/comments\/default\/775464350110360221"},{"rel":"alternate","type":"text/html","href":"https:\/\/sandwalk.blogspot.com\/2020\/10\/undergraduate-education-in-biology-no.html?showComment=1604428480622#c775464350110360221","title":""},{"rel":"related","type":"application/atom+xml","href":"https:\/\/www.blogger.com\/feeds\/37148773\/3483581682344064252\/comments\/default\/3980845448350684265"}],"author":[{"name":{"$t":"dean"},"uri":{"$t":"https:\/\/www.blogger.com\/profile\/08279929296814513986"},"email":{"$t":"noreply@blogger.com"},"gd$image":{"rel":"http://schemas.google.com/g/2005#thumbnail","width":"16","height":"16","src":"https:\/\/img1.blogblog.com\/img\/b16-rounded.gif"}}],"thr$in-reply-to":{"xmlns$thr":"http://purl.org/syndication/thread/1.0","href":"https:\/\/sandwalk.blogspot.com\/2020\/10\/undergraduate-education-in-biology-no.html","ref":"tag:blogger.com,1999:blog-37148773.post-3483581682344064252","source":"http://www.blogger.com/feeds/37148773/posts/default/3483581682344064252","type":"text/html"},"gd$extendedProperty":[{"name":"blogger.itemClass","value":"pid-430226920"},{"name":"blogger.displayTime","value":"Tuesday, November 03, 2020 1:34:00 PM"}]}]}});