tag:blogger.com,1999:blog-37148773.post3225673107514117848..comments2024-03-27T14:50:47.345-04:00Comments on <center>Sandwalk</center>: Happy DNA Day 2023!Larry Moranhttp://www.blogger.com/profile/05756598746605455848noreply@blogger.comBlogger1125tag:blogger.com,1999:blog-37148773.post-72753097781308794452023-04-28T18:19:51.830-04:002023-04-28T18:19:51.830-04:00Details of how advancements of knowledge came abou...Details of how advancements of knowledge came about can guide our thinking about how to advance knowledge in the future. Fine-tuning those details, as in the Cobb-Comfort piece, is thus of great value. However, even more important is the unearthing of scientific aspects, the significance of which did not emerge until much later. <br /><br />For example, in a follow-up paper (1971) Crick advanced the hypothesis that the conventional Watson-Crick duplex might open up in regions with palindrome-like base sequences. so forming stem-loop structures. Decades later Kleckner and her associates saw the possible relevance of this to the problem of how homologous sequences pair for recombination. <br /><br />According to Olby, Crick deemed the legend to a figure in his paper of such importance that he had asked the editors of <i>Nature</i> to deviate from the usual font size. They declined to do so.Donald Forsdykehttps://www.blogger.com/profile/18038104286639798795noreply@blogger.com