tag:blogger.com,1999:blog-37148773.post5741124762831790145..comments2024-03-27T14:50:47.345-04:00Comments on <center>Sandwalk</center>: Rosie Redfield at Evolution Ottawa 2012Larry Moranhttp://www.blogger.com/profile/05756598746605455848noreply@blogger.comBlogger6125tag:blogger.com,1999:blog-37148773.post-40344005084862368502012-07-11T05:37:25.537-04:002012-07-11T05:37:25.537-04:00From the science paper, pg 1165, third column at t...From the science paper, pg 1165, third column at the top. <br /><br />"These measurements therefore specifically demonstrated that the purified DNA extracted from +As/–P cells contained As. Our NanoSIMS analyses, combined with the evidence for intracellular arsenic by ICP-MS and our radiolabeled 73AsO43– experiments, indicated that intracellular AsO43– was incorporated into key biomolecules, specifically DNA."<br /><br />That's a wee bit more than caught up in the hype machine....<br /><br />-The Other JimAnonymousnoreply@blogger.comtag:blogger.com,1999:blog-37148773.post-27945243260073730472012-07-11T04:22:43.875-04:002012-07-11T04:22:43.875-04:00In the fourth paragraph from the end:
"She&#...In the fourth paragraph from the end:<br /><br />"She's right about the fact that the original paper never actually said that DNA replaced phosphorus in DNA but it did strongly imply that this was the logical conclusion."<br /><br />I think you mean to say either "...said that arsenic replaced phosphorus in DNA..." or "... said that DNA replaced phosphorus with arsenic...".greg byshenknoreply@blogger.comtag:blogger.com,1999:blog-37148773.post-88110214509216060012012-07-11T03:08:07.443-04:002012-07-11T03:08:07.443-04:00Seems to me that the title of the paper by Wolfe-S...Seems to me that the title of the paper by Wolfe-Simon, et al., leaves no doubt about what Simon and her collaborators claimed (and still do if they're standing by their paper):<br /><br />"A bacterium that can grow by using arsenic instead of phosphorus." <br /><br />"[I]nstead of" sure doesn't sound the same as "Yet, low amounts of arsenic incorporation may be challenging to find and unstable once cells are opened," she writes, "so may merit comprehensive and systematic efforts with other assays and conditions."<br /><br />Instead of can legitimately be construed as 'replacing'.The whole truthhttps://www.blogger.com/profile/07219999357041824471noreply@blogger.comtag:blogger.com,1999:blog-37148773.post-44237476011556454782012-07-10T22:29:12.475-04:002012-07-10T22:29:12.475-04:00If Anonymous wants to evaluate Rosie Redfield'...If Anonymous wants to evaluate Rosie Redfield's science, Anonymous could go read her papers and her blogging about that work. She has studied DNA uptake by bacteria and "quorum sensing" bacterial communication. On both she takes a decidedly nonstandard and controversial position. Her work on the arsenic issue is a sideline. I attended molecular evolution meetings in Canada for many years. Rosie was always there, always with some new and stimulating results or hypotheses, and always great fun to listen to.Joe Felsensteinhttps://www.blogger.com/profile/06359126552631140000noreply@blogger.comtag:blogger.com,1999:blog-37148773.post-12593254088523030902012-07-10T20:49:26.472-04:002012-07-10T20:49:26.472-04:00Anonymous fail. Not understanding science or the w...Anonymous fail. Not understanding science or the weakness of the publication system today.Don N.noreply@blogger.comtag:blogger.com,1999:blog-37148773.post-9437642657806205282012-07-10T15:07:16.369-04:002012-07-10T15:07:16.369-04:00Frankly, not very impressed with Redfield. Yes, g...Frankly, not very impressed with Redfield. Yes, good job and all proofing the scientific record, but how about making some kind of de novo positive contribution of your own? It's pretty standard stuff for the various non-science hype machines to go into rabid overdrive over the smallest result, and maybe FW-S got caught up in it, but the actual paper is considerably more modest.Anonymousnoreply@blogger.com