Here's the first question. It's based on Gerhart and Kirschner (2007).
What do you think of Kirschner and Gerhart’s "Theory of Facilitated Evolution." Is this something that has to be incorporated into a new extended version of evolutionary theory? What, if any, are the limitations of the theory and what, if any, new insights into evolution does it provide?
Gerhart, J., and Kirschner, M. (2007) The theory of facilitated variation. Proc. Natl. Acad. Sci. USA 104 Suppl 1:8582-8589. [doi: 10.1073/pnas.0701035104]