Monday, May 18, 2009

Monday's Molecule #122

 
Today's molecule is a drug as well as a biological molecule that's found in some species. You need to supply the common name and the correct IUPAC name for this molecule. The stereochemistry isn't shown in the figure but you have to specify it in your answer.

As a drug, this molecule is used to treat a common but life-threatening condition. Identify that condition and name the Nobel Laureate who first described and characterized it.

The first person to identify the molecule and the Nobel Laureate wins a free lunch at the Faculty Club. Previous winners are ineligible for one month from the time they first won the prize.

There are seven ineligible candidates for this week's reward: Mike Fraser of Toronto, Alex Ling of the University of Toronto, Laura Gerth of the University of Notre Dame, Stefan Tarnawsky of the University of Toronto, Dima Klenchin of the University of Wisconsin, Madison, Adam Santoro of the University of Toronto., and Michael Clarkson of Waltham MA (USA).

The Canadians are still ahead in the competition between Canadians the rest of the world but their recent dominance is coming to an end. I want to thank all those smart Canadians who have been holding back in order to give the rest of the world a chance.

I still have one extra free lunch donated by a previous winner (Michael Clarkson) to a deserving undergraduate so I'm going to continue to award an additional free lunch to the first undergraduate student who can accept it. Please indicate in your email message whether you are an undergraduate and whether you can make it for lunch.

THEME:

Nobel Laureates
Send your guess to Sandwalk (sandwalk (at) bioinfo.med.utoronto.ca) and I'll pick the first email message that correctly identifies the molecule and names the Nobel Laureate(s). Note that I'm not going to repeat Nobel Prizes so you might want to check the list of previous Sandwalk postings by clicking on the link in the theme box.

Correct responses will be posted tomorrow.

Comments will be blocked for 24 hours.


1 comment :

  1. (R)-4-(1-hydroxy-
    2-(methylamino)ethyl)benzene-1,2-diol

    a.k.a. epinephrine (adrenaline)

    Earl Sutherland (Nobel Physiology/Medicine 1971) elucidated the role of cAMP as a second messenger in epinephrine signaling

    ReplyDelete